STRINGSTRING
HCDG_03868 HCDG_03868 HCDG_00748 HCDG_00748 HCDG_00843 HCDG_00843 HCDG_00849 HCDG_00849 HCDG_00850 HCDG_00850 HCDG_00867 HCDG_00867 HCDG_00893 HCDG_00893 TRM8 TRM8 HCDG_00933 HCDG_00933 HCDG_00939 HCDG_00939 HCDG_00996 HCDG_00996 HCDG_01119 HCDG_01119 HCDG_00024 HCDG_00024 HCDG_01234 HCDG_01234 HCDG_06262 HCDG_06262 HCDG_05823 HCDG_05823 HCDG_05852 HCDG_05852 HCDG_05868 HCDG_05868 HCDG_05938 HCDG_05938 HCDG_05939 HCDG_05939 HCDG_05966 HCDG_05966 HCDG_05967 HCDG_05967 HCDG_06044 HCDG_06044 HCDG_06081 HCDG_06081 HCDG_06089 HCDG_06089 HCDG_06117 HCDG_06117 HCDG_06323 HCDG_06323 HCDG_06412 HCDG_06412 HCDG_06441 HCDG_06441 HCDG_06442 HCDG_06442 HCDG_06482 HCDG_06482 HCDG_06607 HCDG_06607 HCDG_06633 HCDG_06633 HCDG_06651 HCDG_06651 HCDG_06655 HCDG_06655 HCDG_06658 HCDG_06658 HCDG_06693 HCDG_06693 HCDG_06735 HCDG_06735 HCDG_06748 HCDG_06748 HCDG_06773 HCDG_06773 HCDG_07025 HCDG_07025 HCDG_07565 HCDG_07565 HCDG_07617 HCDG_07617 HCDG_07618 HCDG_07618 HCDG_07347 HCDG_07347 HCDG_07639 HCDG_07639 HCDG_07641 HCDG_07641 HCDG_07697 HCDG_07697 HCDG_07857 HCDG_07857 HCDG_07987 HCDG_07987 HCDG_07998 HCDG_07998 HCDG_08043 HCDG_08043 HCDG_08049 HCDG_08049 HCDG_08071 HCDG_08071 HCDG_08113 HCDG_08113 HCDG_08258 HCDG_08258 HCDG_08372 HCDG_08372 HCDG_08772 HCDG_08772 HCDG_08414 HCDG_08414 HCDG_08415 HCDG_08415 HCDG_08513 HCDG_08513 HCDG_08587 HCDG_08587 HCDG_08606 HCDG_08606 HCDG_08962 HCDG_08962 HCDG_09037 HCDG_09037 HCDG_09094 HCDG_09094 HCDG_09124 HCDG_09124 HCDG_09135 HCDG_09135 HCDG_09148 HCDG_09148 HCDG_09151 HCDG_09151 HCDG_09206 HCDG_09206 HCDG_09384 HCDG_09384 HCDG_09389 HCDG_09389 HCDG_09426 HCDG_09426 HCDG_00125 HCDG_00125 HCDG_00172 HCDG_00172 HCDG_00208 HCDG_00208 HCDG_00251 HCDG_00251 HCDG_01436 HCDG_01436 HCDG_01460 HCDG_01460 HCDG_01461 HCDG_01461 HCDG_00296 HCDG_00296 HCDG_00317 HCDG_00317 HCDG_00351 HCDG_00351 HCDG_00446 HCDG_00446 HCDG_00465 HCDG_00465 HCDG_00480 HCDG_00480 HCDG_00499 HCDG_00499 HCDG_01736 HCDG_01736 HCDG_01819 HCDG_01819 HCDG_01823 HCDG_01823 HCDG_01920 HCDG_01920 HCDG_01925 HCDG_01925 HCDG_01926 HCDG_01926 HCDG_01952 HCDG_01952 HCDG_01982 HCDG_01982 HCDG_02097 HCDG_02097 HCDG_02121 HCDG_02121 HCDG_02260 HCDG_02260 HCDG_02262 HCDG_02262 HCDG_02346 HCDG_02346 HCDG_02431 HCDG_02431 HCDG_02435 HCDG_02435 HCDG_02550 HCDG_02550 HCDG_02624 HCDG_02624 HCDG_02643 HCDG_02643 HCDG_02646 HCDG_02646 HCDG_02717 HCDG_02717 HCDG_02740 HCDG_02740 HCDG_02779 HCDG_02779 HCDG_02818 HCDG_02818 HCDG_03073 HCDG_03073 HCDG_03151 HCDG_03151 HCDG_03949 HCDG_03949 HCDG_03570 HCDG_03570 HCDG_03571 HCDG_03571 HCDG_03633 HCDG_03633 HCDG_03742 HCDG_03742 HCDG_03743 HCDG_03743 HCDG_03744 HCDG_03744 HCDG_04029 HCDG_04029 HCDG_04047 HCDG_04047 HCDG_04050 HCDG_04050 HCDG_04223 HCDG_04223 HCDG_04224 HCDG_04224 HCDG_04274 HCDG_04274 HCDG_04285 HCDG_04285 HCDG_04382 HCDG_04382 HCDG_04398 HCDG_04398 HCDG_04436 HCDG_04436 HCDG_04437 HCDG_04437 HCDG_04805 HCDG_04805 HCDG_04866 HCDG_04866 HCDG_04869 HCDG_04869 HCDG_04919 HCDG_04919 HCDG_05009 HCDG_05009 HCDG_05010 HCDG_05010 HCDG_04536 HCDG_04536 HCDG_04652 HCDG_04652 HCDG_04686 HCDG_04686 HCDG_05278 HCDG_05278 HCDG_05283 HCDG_05283 HCDG_05342 HCDG_05342 HCDG_05391 HCDG_05391 HCDG_05423 HCDG_05423 HCDG_05437 HCDG_05437 HCDG_05041 HCDG_05041 HCDG_05042 HCDG_05042 HCDG_05056 HCDG_05056 HCDG_05140 HCDG_05140 HCDG_05179 HCDG_05179 HCDG_05194 HCDG_05194 HCDG_05592 HCDG_05592 HCDG_05593 HCDG_05593 HCDG_05618 HCDG_05618 HCDG_05622 HCDG_05622 HCDG_05688 HCDG_05688 HCDG_05752 HCDG_05752 HCDG_06191 HCDG_06191 HCDG_06193 HCDG_06193
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_03868SMP-30/CGR1 family protein. (333 aa)
HCDG_00748Threonine dehydratase. (562 aa)
HCDG_00843Isocitrate lyase. (537 aa)
HCDG_00849MFS multidrug resistance transporter. (213 aa)
HCDG_00850MFS multidrug resistance transporter. (98 aa)
HCDG_00867Aminotransferase. (364 aa)
HCDG_00893Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (683 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (344 aa)
HCDG_00933Aspartate aminotransferase. (383 aa)
HCDG_00939Uncharacterized protein. (431 aa)
HCDG_00996Methylmalonate-semialdehyde dehydrogenase. (538 aa)
HCDG_01119Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (524 aa)
HCDG_00024Glyceraldehyde-3-phosphate dehydrogenase. (211 aa)
HCDG_01234S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
HCDG_06262Ribose-5-phosphate isomerase B. (42 aa)
HCDG_05823C6 transcription factor. (752 aa)
HCDG_05852Succinyl-CoA ligase alpha-chain. (645 aa)
HCDG_05868Uncharacterized protein. (361 aa)
HCDG_05938Pribosyltran_N domain-containing protein. (73 aa)
HCDG_05939Ribose-phosphate pyrophosphokinase. (166 aa)
HCDG_05966Acetyl-coenzyme A synthetase. (90 aa)
HCDG_05967Acetyl-coenzyme A synthetase. (252 aa)
HCDG_060442-oxoglutarate dehydrogenase E1 component. (1011 aa)
HCDG_06081Uncharacterized protein. (118 aa)
HCDG_06089TPR domain-containing protein. (402 aa)
HCDG_06117DUF636 domain-containing protein. (163 aa)
HCDG_06323Phosphotransferase. (487 aa)
HCDG_06412Aspartate aminotransferase. (430 aa)
HCDG_06441Ribosome biogenesis protein TSR1. (221 aa)
HCDG_06442Ribosome biogenesis protein TSR1. (562 aa)
HCDG_06482Uncharacterized protein. (278 aa)
HCDG_06607GFA domain-containing protein. (149 aa)
HCDG_06633Phosphoglycerate mutase. (228 aa)
HCDG_06651Malate dehydrogenase. (340 aa)
HCDG_06655Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (490 aa)
HCDG_06658Ribose-phosphate pyrophosphokinase. (515 aa)
HCDG_06693Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (801 aa)
HCDG_06735Triosephosphate isomerase. (170 aa)
HCDG_067483-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (465 aa)
HCDG_06773Dihydroxyacetone kinase. (596 aa)
HCDG_07025Cysteine synthase. (448 aa)
HCDG_07565SET domain-containing protein. (439 aa)
HCDG_07617Nipsnap family protein. (186 aa)
HCDG_07618Uncharacterized protein. (129 aa)
HCDG_07347Phosphotransferase. (621 aa)
HCDG_07639Phosphoserine phosphatase. (357 aa)
HCDG_07641Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (491 aa)
HCDG_07697WD40 domain-containing protein. (552 aa)
HCDG_07857Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (134 aa)
HCDG_07987C6 transcription factor. (226 aa)
HCDG_07998Dihydrolipoamide S-succinyltransferase. (465 aa)
HCDG_08043Dihydrolipoyl dehydrogenase. (481 aa)
HCDG_08049Formamidase. (497 aa)
HCDG_08071Uncharacterized protein. (452 aa)
HCDG_08113Pyridoxal-5'-phosphate-dependent enzyme. (388 aa)
HCDG_08258Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (331 aa)
HCDG_08372C6 zinc finger protein. (731 aa)
HCDG_08772Pyruvate dehydrogenase E1 component alpha subunit. (410 aa)
HCDG_08414Ribulose-phosphate 3-epimerase. (147 aa)
HCDG_08415Ribulose-phosphate 3-epimerase. (84 aa)
HCDG_08513Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (628 aa)
HCDG_08587Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
HCDG_08606Alcohol oxidase. (596 aa)
HCDG_08962Phosphotransferase. (467 aa)
HCDG_09037Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (283 aa)
HCDG_09094Fructose 1,6-bisphosphatase; Belongs to the FBPase class 1 family. (258 aa)
HCDG_09124Arabinan endo-1,5-alpha-L-arabinosidase; Belongs to the glycosyl hydrolase 43 family. (361 aa)
HCDG_09135Uncharacterized protein. (480 aa)
HCDG_09148Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
HCDG_09151Uncharacterized protein. (337 aa)
HCDG_09206Uncharacterized protein. (333 aa)
HCDG_09384Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (590 aa)
HCDG_09389PNPLA domain-containing protein. (757 aa)
HCDG_09426Fumarate hydratase class II. (567 aa)
HCDG_00125Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
HCDG_00172Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (510 aa)
HCDG_00208Pyruvate dehydrogenase complex component Pdx1. (250 aa)
HCDG_002513-hydroxybutyryl CoA dehydrogenase. (321 aa)
HCDG_01436Acetyltransferase. (220 aa)
HCDG_01460NADP-dependent malic enzyme. (365 aa)
HCDG_01461NADP-dependent malic enzyme MaeA. (119 aa)
HCDG_00296Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1128 aa)
HCDG_00317L-serine dehydratase. (359 aa)
HCDG_00351Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
HCDG_00446Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (377 aa)
HCDG_00465Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (710 aa)
HCDG_00480Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1072 aa)
HCDG_00499ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
HCDG_01736Ribose 5-phosphate isomerase A. (274 aa)
HCDG_01819Transketolase TktA. (866 aa)
HCDG_01823SET domain-containing protein. (502 aa)
HCDG_01920Malate synthase; Belongs to the malate synthase family. (539 aa)
HCDG_01925Isocitrate lyase. (600 aa)
HCDG_01926Citrate synthase; Belongs to the citrate synthase family. (470 aa)
HCDG_01952Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (756 aa)
HCDG_01982CLPTM1 domain-containing protein. (525 aa)
HCDG_02097Uncharacterized protein. (371 aa)
HCDG_02121Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (731 aa)
HCDG_02260Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
HCDG_02262Phosphoglycerate mutase. (521 aa)
HCDG_02346Uncharacterized protein. (67 aa)
HCDG_02431Uncharacterized protein. (681 aa)
HCDG_02435Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (377 aa)
HCDG_02550Pyruvate kinase; Belongs to the pyruvate kinase family. (306 aa)
HCDG_02624Enolase. (418 aa)
HCDG_02643Uncharacterized protein. (115 aa)
HCDG_02646Uncharacterized protein. (207 aa)
HCDG_02717Uncharacterized protein. (345 aa)
HCDG_02740Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (143 aa)
HCDG_02779Succinate dehydrogenase cytochrome b560 subunit. (188 aa)
HCDG_02818Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (772 aa)
HCDG_03073S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
HCDG_031516-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (265 aa)
HCDG_03949Ribose-phosphate pyrophosphokinase II. (786 aa)
HCDG_03570Nuclear export protein Noc3. (189 aa)
HCDG_03571Nuclear export protein Noc3. (221 aa)
HCDG_03633Probable acetate kinase. (428 aa)
HCDG_03742Uncharacterized protein. (471 aa)
HCDG_03743Uncharacterized protein. (325 aa)
HCDG_03744Uncharacterized protein. (344 aa)
HCDG_04029D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (598 aa)
HCDG_04047Alanine transaminase. (531 aa)
HCDG_04050Phosphoenolpyruvate carboxykinase AcuF. (432 aa)
HCDG_04223Acetyltransferase. (204 aa)
HCDG_04224Acetyltransferase. (170 aa)
HCDG_04274Uncharacterized protein. (502 aa)
HCDG_042856-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (463 aa)
HCDG_04382Uncharacterized protein. (412 aa)
HCDG_04398Uncharacterized protein. (307 aa)
HCDG_04436Carboxylase:pyruvate/acetyl-CoA/propionyl-CoA. (634 aa)
HCDG_04437Methylmalonyl-CoA decarboxylase. (182 aa)
HCDG_04805Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (713 aa)
HCDG_04866Succinate dehydrogenase flavoprotein. (126 aa)
HCDG_04869Succinate dehydrogenase cytochrome b560 subunit. (187 aa)
HCDG_04919Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
HCDG_05009Uncharacterized protein. (222 aa)
HCDG_05010Uncharacterized protein. (356 aa)
HCDG_04536Gluconolactonase. (366 aa)
HCDG_04652Cysteine synthase (O-acetylserine (Thiol)-lyase). (403 aa)
HCDG_04686Enoyl-CoA hydratase. (273 aa)
HCDG_05278L-lactate dehydrogenase. (313 aa)
HCDG_05283Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
HCDG_05342Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
HCDG_05391Lactonohydrolase. (144 aa)
HCDG_05423Uncharacterized protein. (237 aa)
HCDG_05437D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (481 aa)
HCDG_05041O-acetylhomoserine (Thiol)-lyase. (50 aa)
HCDG_05042O-acetyl-L-homoserine sulfhydrylase. (264 aa)
HCDG_05056Citrate synthase; Belongs to the citrate synthase family. (473 aa)
HCDG_05140Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (330 aa)
HCDG_05179Phosphoserine aminotransferase. (436 aa)
HCDG_05194Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (420 aa)
HCDG_05592Uncharacterized protein. (311 aa)
HCDG_05593Acetoacetyl-CoA reductase. (778 aa)
HCDG_05618Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (437 aa)
HCDG_05622Catalase isozyme P. (503 aa)
HCDG_05688Phosphotransferase. (612 aa)
HCDG_05752Glucose-6-phosphate isomerase; Belongs to the GPI family. (499 aa)
HCDG_06191Aspartate aminotransferase. (251 aa)
HCDG_06193Uncharacterized protein. (124 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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