STRINGSTRING
AEF85631.1 AEF85631.1 malQ malQ AEF85120.1 AEF85120.1 AEF84610.1 AEF84610.1 AEF85178.1 AEF85178.1 AEF84676.1 AEF84676.1 AEF86844.1 AEF86844.1 AEF83705.1 AEF83705.1 pgk_2 pgk_2 AEF86496.1 AEF86496.1 AEF85559.1 AEF85559.1 pfkA pfkA pyk pyk AEF84333.1 AEF84333.1 eno eno glgX glgX ilvB ilvB ilvD ilvD leuB leuB AEF84687.1 AEF84687.1 leuA leuA ilvC ilvC ilvN ilvN accA_2 accA_2 accD_2 accD_2 AEF86632.1 AEF86632.1 fba fba ackA ackA accA_1 accA_1 accD_1 accD_1 AEF85731.1 AEF85731.1 AEF84024.1 AEF84024.1 AEF85360.1 AEF85360.1 fabF fabF fabG fabG AEF86309.1 AEF86309.1 fabH fabH ttdA ttdA fumB fumB AEF84107.1 AEF84107.1 AEF84419.1 AEF84419.1 AEF85681.1 AEF85681.1 AEF86234.1 AEF86234.1 AEF83715.1 AEF83715.1 dmpG dmpG AEF84834.1 AEF84834.1 AEF84644.1 AEF84644.1 AEF85062.1 AEF85062.1 AEF86009.1 AEF86009.1 AEF86845.1 AEF86845.1 pfp pfp AEF85652.1 AEF85652.1 leuC leuC manA manA AEF85705.1 AEF85705.1 oadA oadA AEF84737.1 AEF84737.1 AEF85659.1 AEF85659.1 rpe rpe AEF86315.1 AEF86315.1 AEF86734.1 AEF86734.1 AEF83675.1 AEF83675.1 AEF86735.1 AEF86735.1 AEF84499.1 AEF84499.1 AEF85302.1 AEF85302.1 AEF83826.1 AEF83826.1 AEF84773.1 AEF84773.1 AEF86931.1 AEF86931.1 glgC glgC AEF84516.1 AEF84516.1 pta pta rpiB rpiB nifJ nifJ glgA glgA pgi pgi ppdK ppdK AEF85677.1 AEF85677.1 tpiA tpiA pgk_1 pgk_1 gap gap AEF84155.1 AEF84155.1 AEF85696.1 AEF85696.1 malP malP AEF85124.1 AEF85124.1 pckG pckG AEF83635.1 AEF83635.1 AEF85475.1 AEF85475.1 AEF84129.1 AEF84129.1 nagB nagB nagA nagA ilvE ilvE deoC deoC AEF84370.1 AEF84370.1 AEF85594.1 AEF85594.1 vorB vorB AEF84656.1 AEF84656.1 pfkA-2 pfkA-2 AEF86314.1 AEF86314.1 AEF85076.1 AEF85076.1 AEF86558.1 AEF86558.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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AEF85631.1Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (570 aa)
malQ4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217. (508 aa)
AEF85120.14-alpha-glucanotransferase (Amylomaltase)(Disproportionating enzyme) (D-enzyme); Identified by match to protein family HMM PF02446. (676 aa)
AEF84610.1Alpha amylase catalytic region; Identified by match to protein family HMM PF00128. (1294 aa)
AEF85178.1Transketolase; Identified by match to protein family HMM PF00456. (278 aa)
AEF84676.1Transketolase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (313 aa)
AEF86844.1Malate dehydrogenase (oxaloacetate-decarboxylating); Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. (484 aa)
AEF83705.1Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. (342 aa)
pgk_2Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (418 aa)
AEF86496.1Transketolase; Identified by match to protein family HMM PF00456. (275 aa)
AEF85559.1Transketolase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (316 aa)
pfkADiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (452 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (597 aa)
AEF84333.1Acylphosphatase; Identified by match to protein family HMM PF00708. (98 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
glgXGlycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family. (717 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; Belongs to the TPP enzyme family. (599 aa)
ilvDDihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (553 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (377 aa)
AEF84687.12-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM PF08502; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. (553 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (523 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
ilvNAcetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119. (171 aa)
accA_2acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (266 aa)
accD_2acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (272 aa)
AEF86632.1Aminotransferase, class I and II; Identified by match to protein family HMM PF00155. (448 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (332 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (445 aa)
accA_1acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (309 aa)
accD_1acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (274 aa)
AEF85731.1Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786. (443 aa)
AEF84024.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (197 aa)
AEF85360.1Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Identified by match to protein family HMM PF07977. (139 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
AEF86309.1Malonyl CoA-acyl carrier protein transacylase (MCT); Identified by match to protein family HMM PF00698. (324 aa)
fabHBeta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (354 aa)
ttdAFumarate hydratase; Identified by match to protein family HMM PF05681; match to protein family HMM TIGR00722. (279 aa)
fumBFumarate hydratase, class I; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. (190 aa)
AEF84107.1Transketolase C- section; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (311 aa)
AEF84419.1Transketolase; Identified by match to protein family HMM PF00456. (278 aa)
AEF85681.12-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Identified by match to protein family HMM PF00561. (274 aa)
AEF86234.12-keto-4-pentenoate hydratase (2-hydroxypentadienoic acidhydratase); Identified by match to protein family HMM PF01689. (260 aa)
AEF83715.1Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (288 aa)
dmpG4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (335 aa)
AEF84834.1Catechol 2,3 dioxygenase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR03211. (308 aa)
AEF84644.1Hexokinase; Identified by match to protein family HMM PF00349; match to protein family HMM PF03727. (451 aa)
AEF85062.1Putative amino acid transporter; Identified by match to protein family HMM PF00324. (457 aa)
AEF86009.1Glycoside hydrolase, family 57; Identified by match to protein family HMM PF03065; match to protein family HMM PF09210; Belongs to the glycosyl hydrolase 57 family. (526 aa)
AEF86845.1Dihydroxy-acid dehydratase (DAD); Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. (572 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (551 aa)
AEF85652.13-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Identified by match to protein family HMM PF00694; Belongs to the LeuD family. (174 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (430 aa)
manAMannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218. (415 aa)
AEF85705.1Oxaloacetate decarboxylase, subunit beta; Identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109. (467 aa)
oadAOxaloacetate decarboxylase alpha subunit; Identified by match to protein family HMM PF00364; match to protein family HMM PF00682; match to protein family HMM PF02436; match to protein family HMM TIGR01108. (685 aa)
AEF84737.1Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (86 aa)
AEF85659.1Putative phosphomannomutase; Identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (592 aa)
rpeRibulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family. (249 aa)
AEF86315.1Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family. (366 aa)
AEF86734.1Alpha-amylase; Identified by match to protein family HMM PF03065. (630 aa)
AEF83675.1Identified by match to protein family HMM PF00330. (771 aa)
AEF86735.1ATPase. (432 aa)
AEF84499.1Pentaglycine interpeptide bridge formation protein; Identified by match to protein family HMM PF02388. (372 aa)
AEF85302.1Hypothetical protein; Identified by glimmer; putative. (171 aa)
AEF83826.1Transcriptional regulator, XRE family with cupin sensor; Identified by match to protein family HMM PF01381; match to protein family HMM PF07883. (184 aa)
AEF84773.1Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (580 aa)
AEF86931.1Putative sucrose phosphorylase (Sucroseglucosyltransferase); Identified by match to protein family HMM PF00128. (611 aa)
glgCGlucose-1-phosphate adenylyltransferase; Identified by match to protein family HMM PF00483; match to protein family HMM TIGR02091. (424 aa)
AEF84516.1Pyruvate, phosphate dikinase (Pyruvate, orthophosphatedikinase); Identified by match to protein family HMM PF00391; match to protein family HMM PF02896. (585 aa)
ptaPhosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651. (332 aa)
rpiBRibose-5-phosphate isomerase B; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. (151 aa)
nifJPyruvate:ferredoxin (flavodoxin) oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. (1187 aa)
glgAGlycogen synthase (Starch [bacterial glycogen]synthase); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (493 aa)
pgiGlucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. (524 aa)
ppdKPyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828. (1002 aa)
AEF85677.1Citrate synthase domain protein; Identified by match to protein family HMM PF00285. (447 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
pgk_1Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (420 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (352 aa)
AEF84155.1Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (399 aa)
AEF85696.1Identified by match to protein family HMM PF02878. (637 aa)
malPMaltodextrin phosphorylase; Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. (846 aa)
AEF85124.12-isopropylmalate synthase (Alpha-isopropylmalatesynthase) (Alpha-IPM synthetase); Identified by match to protein family HMM PF00682; Belongs to the alpha-IPM synthase/homocitrate synthase family. (554 aa)
pckGPhosphoenolpyruvate carboxykinase (ATP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (606 aa)
AEF83635.1Aldehyde-alcohol dehydrogenase 2; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (878 aa)
AEF85475.13-methylitaconate isomerase; Identified by match to protein family HMM PF04303. (386 aa)
AEF84129.1Identified by match to protein family HMM PF00330; match to protein family HMM PF00694. (764 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (263 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221. (378 aa)
ilvEBranched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (361 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (245 aa)
AEF84370.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Identified by match to protein family HMM PF01558. (177 aa)
AEF85594.12-oxoglutarate oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775. (259 aa)
vorB2-oxoglutarate oxidoreductase, alpha subunit; Identified by match to protein family HMM PF01855; match to protein family HMM PF02780. (376 aa)
AEF84656.1Conserved domain protein; Identified by match to protein family HMM PF00037. (76 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (367 aa)
AEF86314.1Fructokinase; Identified by match to protein family HMM PF00294. (326 aa)
AEF85076.1Phosphoribosylpyrophosphate synthetase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family. (410 aa)
AEF86558.1Possible maltodextrin glucosidase; Identified by match to protein family HMM PF00128. (489 aa)
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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