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| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (210 aa) |
| | metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1243 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (263 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (291 aa) |
| | AEF85631.1 | Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (570 aa) |
| | AEF84275.1 | Dtdp-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (300 aa) |
| | malQ | 4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217. (508 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (478 aa) |
| | AEF85578.1 | Putative adenylosuccinate lyase; Identified by match to protein family HMM PF00206. (490 aa) |
| | AEF85120.1 | 4-alpha-glucanotransferase (Amylomaltase)(Disproportionating enzyme) (D-enzyme); Identified by match to protein family HMM PF02446. (676 aa) |
| | AEF85914.1 | Sulfate adenylyltransferase subunit 1; Identified by match to protein family HMM PF00009. (461 aa) |
| | AEF86687.1 | Sulfate adenylyltransferase subunit 2; Identified by match to protein family HMM PF01507. (298 aa) |
| | AEF84480.1 | Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (400 aa) |
| | AEF84001.1 | Siroheme synthase; Identified by match to protein family HMM TIGR01470. (192 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (333 aa) |
| | AEF85381.1 | uroporphyrinogen-III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. (526 aa) |
| | hemB | Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (328 aa) |
| | AEF83968.1 | Threonine synthase; Identified by match to protein family HMM PF00291. (434 aa) |
| | AEF85178.1 | Transketolase; Identified by match to protein family HMM PF00456. (278 aa) |
| | AEF84676.1 | Transketolase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (313 aa) |
| | AEF86997.1 | Pyrophosphatase PpaX. (206 aa) |
| | asnB | Asparagine synthase (glutamine-hydrolyzing); Identified by match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536. (629 aa) |
| | metA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (305 aa) |
| | AEF83663.1 | Anthranilate synthase component 1 (Anthranilate synthasecomponent I); Identified by match to protein family HMM PF00425; match to protein family HMM PF04715. (502 aa) |
| | AEF84932.1 | Para-aminobenzoate/anthranilate synthase glutamine amidotransferasecomponent II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. (191 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. (297 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (402 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa) |
| | AEF83705.1 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. (342 aa) |
| | pgk_2 | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (418 aa) |
| | AEF83751.1 | Inositol 2-dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894. (376 aa) |
| | AEF86496.1 | Transketolase; Identified by match to protein family HMM PF00456. (275 aa) |
| | AEF85559.1 | Transketolase; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (316 aa) |
| | AEF84999.1 | Inositol 2-dehydrogenase; Identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447. (337 aa) |
| | thrC | Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (454 aa) |
| | AEF86864.1 | Conserved hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (459 aa) |
| | AEF84638.1 | Putative uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (327 aa) |
| | pfkA | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (452 aa) |
| | ndk-2 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Identified by match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (355 aa) |
| | AEF84440.1 | Cystathionine gamma-lyase; Identified by match to protein family HMM PF01053. (381 aa) |
| | AEF85447.1 | Cystathionine gamma-lyase; Identified by match to protein family HMM PF01053. (410 aa) |
| | AEF86509.1 | Putative Fe-S oxidoreductase; Identified by match to protein family HMM PF04055. (410 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa) |
| | pyk | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (597 aa) |
| | AEF87010.1 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. (275 aa) |
| | AEF84210.1 | Identified by match to protein family HMM PF01048. (270 aa) |
| | AEF86106.1 | Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (350 aa) |
| | AEF83883.1 | Uroporphyrinogen decarboxylase; Identified by match to protein family HMM PF01208; Belongs to the uroporphyrinogen decarboxylase family. (345 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa) |
| | AEF85025.1 | Phosphoglycolate phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. (244 aa) |
| | AEF83836.1 | Cystathionine gamma-synthase; Identified by match to protein family HMM PF01053. (417 aa) |
| | glgX | Glycogen debranching enzyme GlgX; Identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100; Belongs to the glycosyl hydrolase 13 family. (717 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa) |
| | deoD | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. (234 aa) |
| | pheA | 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM PF00800; match to protein family HMM PF01842; match to protein family HMM TIGR01361. (652 aa) |
| | ilvB | Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; Belongs to the TPP enzyme family. (599 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (553 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (377 aa) |
| | AEF84687.1 | 2-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM PF08502; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. (553 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (523 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa) |
| | ilvN | Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119. (171 aa) |
| | accA_2 | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (266 aa) |
| | accD_2 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (272 aa) |
| | AEF86632.1 | Aminotransferase, class I and II; Identified by match to protein family HMM PF00155. (448 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | AEF86136.1 | Phosphoglycolate phosphatase; Identified by match to protein family HMM PF00702. (221 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa) |
| | AEF86460.1 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. (1374 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (332 aa) |
| | AEF84377.1 | L-allo-threonine aldolase (L-allo-TA) (L-allo-threonineacetaldehyde-lyase); Identified by match to protein family HMM PF01212. (348 aa) |
| | AEF86609.1 | Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase) (GMP); Identified by match to protein family HMM PF00483. (389 aa) |
| | dapL | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (401 aa) |
| | AEF86980.1 | Diaminopimelate decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784. (423 aa) |
| | ispE | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (351 aa) |
| | AEF86461.1 | Methionine gamma-lyase (L-methioninase); Identified by match to protein family HMM PF01053. (402 aa) |
| | accA_1 | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (309 aa) |
| | accD_1 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (274 aa) |
| | AEF85731.1 | Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786. (443 aa) |
| | AEF84024.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (197 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | AEF86309.1 | Malonyl CoA-acyl carrier protein transacylase (MCT); Identified by match to protein family HMM PF00698. (324 aa) |
| | ttdA | Fumarate hydratase; Identified by match to protein family HMM PF05681; match to protein family HMM TIGR00722. (279 aa) |
| | fumB | Fumarate hydratase, class I; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. (190 aa) |
| | AEF84107.1 | Transketolase C- section; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (311 aa) |
| | AEF84419.1 | Transketolase; Identified by match to protein family HMM PF00456. (278 aa) |
| | AEF85608.1 | Putative methyltransferase CmuC; Belongs to the uroporphyrinogen decarboxylase family. (405 aa) |
| | AEF85136.1 | Periplasmic beta-glucosidase/beta-xylosidase; Identified by match to protein family HMM PF00933; match to protein family HMM PF01915. (740 aa) |
| | AEF84644.1 | Hexokinase; Identified by match to protein family HMM PF00349; match to protein family HMM PF03727. (451 aa) |
| | AEF86887.1 | Hypothetical protein; Identified by glimmer; putative. (537 aa) |
| | AEF86474.1 | Protein UshA; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (523 aa) |
| | AEF86084.1 | Alanine racemase, N- domain protein; Identified by match to protein family HMM PF01168. (377 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (315 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (291 aa) |
| | AEF86009.1 | Glycoside hydrolase, family 57; Identified by match to protein family HMM PF03065; match to protein family HMM PF09210; Belongs to the glycosyl hydrolase 57 family. (526 aa) |
| | AEF86091.1 | Beta-galactosidase; Identified by match to protein family HMM PF00232; match to protein family HMM TIGR03356. (449 aa) |
| | AEF86845.1 | Dihydroxy-acid dehydratase (DAD); Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family. (572 aa) |
| | AEF84609.1 | Beta-galactosidase; Identified by match to protein family HMM PF00232; match to protein family HMM TIGR03356. (460 aa) |
| | pfp | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (551 aa) |
| | AEF85652.1 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Identified by match to protein family HMM PF00694; Belongs to the LeuD family. (174 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (430 aa) |
| | manA | Mannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218. (415 aa) |
| | AEF85659.1 | Putative phosphomannomutase; Identified by match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (592 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family. (249 aa) |
| | AEF86315.1 | Ribose-phosphate pyrophosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family. (366 aa) |
| | AEF86734.1 | Alpha-amylase; Identified by match to protein family HMM PF03065. (630 aa) |
| | AEF83526.1 | Putative riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01467; match to protein family HMM PF06574. (262 aa) |
| | AEF83675.1 | Identified by match to protein family HMM PF00330. (771 aa) |
| | AEF86535.1 | Putative 3-dehydroquinate dehydratase, type 1/shikimate 5-dehydrogenase; Identified by match to protein family HMM PF01487; match to protein family HMM PF01488; match to protein family HMM PF08501. (506 aa) |
| | AEF84773.1 | Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (580 aa) |
| | AEF85951.1 | Putative hydroxypyruvate reductase; Identified by match to protein family HMM PF05161. (415 aa) |
| | AEF86962.1 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. (143 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Identified by match to protein family HMM PF00483; match to protein family HMM TIGR02091. (424 aa) |
| | AEF84516.1 | Pyruvate, phosphate dikinase (Pyruvate, orthophosphatedikinase); Identified by match to protein family HMM PF00391; match to protein family HMM PF02896. (585 aa) |
| | AEF84700.1 | Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-agp acyltransferase; 1-agpat; lysophosphatidic acidacyltransferase; lpaat; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (242 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa) |
| | rpiB | Ribose-5-phosphate isomerase B; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. (151 aa) |
| | AEF84287.1 | Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa) |
| | nifJ | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. (1187 aa) |
| | glgA | Glycogen synthase (Starch [bacterial glycogen]synthase); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (493 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. (524 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828. (1002 aa) |
| | AEF84006.1 | 3-dehydroquinate synthase; Identified by match to protein family HMM PF01761. (377 aa) |
| | AEF84551.1 | Phosphoenolpyruvate mutase; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR02320. (432 aa) |
| | aepY | Phosphonopyruvate decarboxylase; Identified by match to protein family HMM PF02775; match to protein family HMM TIGR03297. (373 aa) |
| | AEF85343.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Identified by match to protein family HMM PF00908. (179 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (177 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (295 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (373 aa) |
| | AEF86387.1 | Conserved hypothetical protein; Identified by match to protein family HMM PF00483; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662. (435 aa) |
| | aroH | Chorismate mutase; Identified by match to protein family HMM PF07736; match to protein family HMM TIGR01796. (123 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (551 aa) |
| | AEF85677.1 | Citrate synthase domain protein; Identified by match to protein family HMM PF00285. (447 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (352 aa) |
| | miaA | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (332 aa) |
| | AEF84645.1 | 2-oxoglutarate decarboxylase; Identified by match to protein family HMM PF02776. (972 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (359 aa) |
| | AEF85087.1 | Aldose 1-epimerase (Mutarotase); Converts alpha-aldose to the beta-anomer. (350 aa) |
| | AEF84155.1 | Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (399 aa) |
| | uppS | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (247 aa) |
| | cdsA_2 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148. (284 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (382 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | AEF83830.1 | Aspartate aminotransferase; Identified by match to protein family HMM PF00155. (405 aa) |
| | AEF85696.1 | Identified by match to protein family HMM PF02878. (637 aa) |
| | AEF85593.1 | Histidinol phosphate phosphatase, HisJ; Identified by match to protein family HMM PF02811; match to protein family HMM TIGR01856; Belongs to the PHP hydrolase family. HisK subfamily. (292 aa) |
| | malP | Maltodextrin phosphorylase; Identified by match to protein family HMM PF00343; match to protein family HMM TIGR02094. (846 aa) |
| | AEF84522.1 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. (847 aa) |
| | surE | 5'-nucleotidase SurE (Nucleoside 5'-monophosphatephosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (260 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (500 aa) |
| | AEF83792.1 | UshA protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (516 aa) |
| | AEF85124.1 | 2-isopropylmalate synthase (Alpha-isopropylmalatesynthase) (Alpha-IPM synthetase); Identified by match to protein family HMM PF00682; Belongs to the alpha-IPM synthase/homocitrate synthase family. (554 aa) |
| | AEF86846.1 | Putative 5'-Nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (491 aa) |
| | AEF84490.1 | Lysine-sensitive aspartokinase 3 (Lysine-sensitiveaspartokinase III) (Aspartate kinase III); Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (451 aa) |
| | dapB | Dihydrodipicolinate reductase; Identified by match to protein family HMM PF01113; match to protein family HMM PF05173; match to protein family HMM TIGR00036; Belongs to the DapB family. (269 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (310 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF01118; match to protein family HMM PF02774; match to protein family HMM TIGR00978; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa) |
| | AEF86807.1 | Uroporphyrinogen decarboxylase (URO-D) superfamily; Identified by match to protein family HMM PF01208; Belongs to the uroporphyrinogen decarboxylase family. (333 aa) |
| | AEF83655.1 | Hypothetical protein; Identified by glimmer; putative; Belongs to the uroporphyrinogen decarboxylase family. (348 aa) |
| | thrH | Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137. (205 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (ATP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (606 aa) |
| | AEF85600.1 | Decarboxylase, pyridoxal-dependent family; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (389 aa) |
| | AEF85419.1 | (S)-2-hydroxy-acid oxidase; Identified by match to protein family HMM PF01070; match to protein family HMM PF01180. (299 aa) |
| | hisD | Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (722 aa) |
| | hisC | Histidinol-phosphate transaminase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (353 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (266 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. (208 aa) |
| | AEF85012.1 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). (284 aa) |
| | aroF | 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM TIGR01361. (341 aa) |
| | AEF84851.1 | Prephenate dehydrogenase; Identified by match to protein family HMM PF02153. (288 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (456 aa) |
| | AEF83635.1 | Aldehyde-alcohol dehydrogenase 2; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (878 aa) |
| | AEF84129.1 | Identified by match to protein family HMM PF00330; match to protein family HMM PF00694. (764 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (380 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) |
| | AEF83976.1 | Acetylornithine transaminase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707. (454 aa) |
| | argG | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (433 aa) |
| | argH | Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838. (468 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (361 aa) |
| | AEF84370.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Identified by match to protein family HMM PF01558. (177 aa) |
| | AEF85594.1 | 2-oxoglutarate oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775. (259 aa) |
| | vorB | 2-oxoglutarate oxidoreductase, alpha subunit; Identified by match to protein family HMM PF01855; match to protein family HMM PF02780. (376 aa) |
| | AEF84656.1 | Conserved domain protein; Identified by match to protein family HMM PF00037. (76 aa) |
| | gltB | Glutamate synthase, large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. (1579 aa) |
| | AEF84988.1 | Glutamate synthase [NADH] (nadh-gogat); Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. (487 aa) |
| | AEF84187.1 | Putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (651 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (367 aa) |
| | AEF84201.1 | Putative 5'-Nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (493 aa) |
| | AEF86314.1 | Fructokinase; Identified by match to protein family HMM PF00294. (326 aa) |
| | AEF85146.1 | Serine acetyltransferase, plasmid (SAT); Identified by match to protein family HMM PF00132. (294 aa) |
| | AEF83708.1 | HAD-superfamily hydrolase, subfamily IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549. (225 aa) |
| | AEF85076.1 | Phosphoribosylpyrophosphate synthetase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251; Belongs to the ribose-phosphate pyrophosphokinase family. (410 aa) |
| | AEF86558.1 | Possible maltodextrin glucosidase; Identified by match to protein family HMM PF00128. (489 aa) |
| | AEF86726.1 | Serine acetyltransferase, plasmid; Identified by match to protein family HMM PF00132. (319 aa) |
| | cysK | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. (306 aa) |
| | argA | Amino-acid N-acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01890; Belongs to the acetyltransferase family. (450 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (443 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142. (553 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (203 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (366 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (239 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | AEF86211.1 | Phosphoglycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (391 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (368 aa) |
| | AEF86761.1 | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. (501 aa) |
| | AEF85683.1 | Glycine dehydrogenase (decarboxylating); Identified by match to protein family HMM PF01212; match to protein family HMM PF02347; overlaps another CDS with the same product name. (477 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (449 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (361 aa) |
