STRINGSTRING
ppdK ppdK AEF83204.1 AEF83204.1 oadA oadA AEF81038.1 AEF81038.1 AEF83145.1 AEF83145.1 AEF80680.1 AEF80680.1 AEF81235.1 AEF81235.1 AEF81922.1 AEF81922.1 AEF82941.1 AEF82941.1 ilvE ilvE ilvN ilvN ilvC ilvC leuA leuA AEF80811.1 AEF80811.1 leuB leuB ilvD ilvD ilvB ilvB AEF81138.1 AEF81138.1 AEF80868.1 AEF80868.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppdKPyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828. (966 aa)
AEF83204.1Oxaloacetate decarboxylase, subunit beta; Identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109. (468 aa)
oadAOxaloacetate decarboxylase alpha subunit; Identified by match to protein family HMM PF00364; match to protein family HMM PF00682; match to protein family HMM PF02436; match to protein family HMM TIGR01108. (681 aa)
AEF81038.1Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (84 aa)
AEF83145.1Oxaloacetate decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (87 aa)
AEF80680.1Oxaloacetate decarboxylase beta chain; Identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109. (379 aa)
AEF81235.13-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Identified by match to protein family HMM PF00694; Belongs to the LeuD family. (174 aa)
AEF81922.13-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Identified by match to protein family HMM PF00330; match to protein family HMM TIGR01343; match to protein family HMM TIGR02086; Belongs to the aconitase/IPM isomerase family. (427 aa)
AEF82941.1Malate dehydrogenase (oxaloacetate-decarboxylating); Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. (484 aa)
ilvEBranched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (362 aa)
ilvNAcetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119. (176 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (512 aa)
AEF80811.12-isopropylmalate synthase/homocitrate synthase family protein; Identified by match to protein family HMM PF00682; match to protein family HMM PF08502; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. (533 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (383 aa)
ilvDDihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (552 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. (583 aa)
AEF81138.12-isopropylmalate synthase (Alpha-isopropylmalatesynthase) (Alpha-IPM synthetase); Identified by match to protein family HMM PF00682; Belongs to the alpha-IPM synthase/homocitrate synthase family. (521 aa)
AEF80868.1Aspartate aminotransferase; Identified by match to protein family HMM PF00155. (405 aa)
Your Current Organism:
Treponema azotonutricium
NCBI taxonomy Id: 545695
Other names: T. azotonutricium ZAS-9, Treponema azotonutricium ZAS-9, Treponema azotonutricium str. ZAS-9, Treponema azotonutricium strain ZAS-9, Treponema sp. ZAS-9
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