STRINGSTRING
leuB leuB AEF81235.1 AEF81235.1 AEF81922.1 AEF81922.1 leuA leuA AEF81138.1 AEF81138.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (383 aa)
AEF81235.13-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Identified by match to protein family HMM PF00694; Belongs to the LeuD family. (174 aa)
AEF81922.13-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Identified by match to protein family HMM PF00330; match to protein family HMM TIGR01343; match to protein family HMM TIGR02086; Belongs to the aconitase/IPM isomerase family. (427 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (512 aa)
AEF81138.12-isopropylmalate synthase (Alpha-isopropylmalatesynthase) (Alpha-IPM synthetase); Identified by match to protein family HMM PF00682; Belongs to the alpha-IPM synthase/homocitrate synthase family. (521 aa)
Your Current Organism:
Treponema azotonutricium
NCBI taxonomy Id: 545695
Other names: T. azotonutricium ZAS-9, Treponema azotonutricium ZAS-9, Treponema azotonutricium str. ZAS-9, Treponema azotonutricium strain ZAS-9, Treponema sp. ZAS-9
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