STRINGSTRING
atpB atpB AEF82234.1 AEF82234.1 atpA-2 atpA-2 atpB-2 atpB-2 AEF82290.1 AEF82290.1 AEF82572.1 AEF82572.1 dacA dacA AEF81250.1 AEF81250.1 AEF82144.1 AEF82144.1 AEF80362.1 AEF80362.1 pfp pfp AEF80900.1 AEF80900.1 fliI fliI fba fba pgi pgi gpmI gpmI AEF82186.1 AEF82186.1 AEF80993.1 AEF80993.1 pta pta AEF81132.1 AEF81132.1 AEF81261.1 AEF81261.1 accD accD accA accA adk adk AEF80384.1 AEF80384.1 purA purA guaB guaB AEF80564.1 AEF80564.1 AEF80071.1 AEF80071.1 pfkA pfkA ndk ndk AEF80417.1 AEF80417.1 coaE coaE AEF82945.1 AEF82945.1 purD purD purH purH purN purN purM purM purF purF purC purC purE purE AEF82993.1 AEF82993.1 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE eno eno AEF83085.1 AEF83085.1 ackA ackA AEF81397.1 AEF81397.1 AEF83472.1 AEF83472.1 coaD coaD AEF81482.1 AEF81482.1 gap gap pgk pgk AEF82464.1 AEF82464.1 atpA-3 atpA-3 atpB-3 atpB-3 atpD-2 atpD-2 AEF81923.1 AEF81923.1 pfkA-2 pfkA-2 apt apt pyk pyk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (253 aa)
AEF82234.1ATP synthase, subunit E. (203 aa)
atpA-2V-type sodium ATP synthase, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (586 aa)
atpB-2V-type sodium ATP synthase, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (432 aa)
AEF82290.1V-type ATPase, D subunit; Identified by match to protein family HMM PF01813; match to protein family HMM TIGR00309. (206 aa)
AEF82572.1Hypothetical protein; Identified by glimmer; putative. (229 aa)
dacAConserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (282 aa)
AEF81250.1Probable fructose-bisphosphate aldolase 1; Identified by match to protein family HMM PF01116. (301 aa)
AEF82144.1Phosphoribosyl transferase domain protein; Identified by match to protein family HMM PF00156. (209 aa)
AEF80362.1Hypothetical protein; Identified by glimmer; putative. (203 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (551 aa)
AEF80900.1Adenylate kinase. (312 aa)
fliIFlagellar protein export ATPase FliI; Identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496. (486 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (332 aa)
pgiGlucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. (529 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (560 aa)
AEF82186.1Nucleoside-diphosphate kinase; Identified by match to protein family HMM PF00334. (395 aa)
AEF80993.1Hexokinase; Identified by match to protein family HMM PF00349; match to protein family HMM PF03727. (450 aa)
ptaPhosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651. (331 aa)
AEF81132.1RelA/SpoT domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF04607; match to protein family HMM PF07719. (407 aa)
AEF81261.1Identified by match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02655. (519 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (259 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (306 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (208 aa)
AEF80384.1GMP synthase (glutamine-hydrolyzing); Identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888. (529 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (408 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (478 aa)
AEF80564.1Putative adenylosuccinate lyase; Identified by match to protein family HMM PF00206. (488 aa)
AEF80071.1CO dehydrogenase/acetyl-CoA synthase delta subunit; Identified by match to protein family HMM PF03599; match to protein family HMM PF04060. (443 aa)
pfkADiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (447 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa)
AEF80417.1Type II pantothenate kinase (Pantothenic acid kinase)(PanK-II). (267 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa)
AEF82945.1Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (564 aa)
purDPhosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (441 aa)
purHBifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. (548 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (206 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (372 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (473 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (239 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa)
AEF82993.1Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. (1307 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (141 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (461 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (303 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (500 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (178 aa)
atpFF0F1-type ATP synthase b subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (169 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (72 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
AEF83085.1C4 zinc finger domain protein, DksA/TraR family; Identified by match to protein family HMM PF01258. (118 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (445 aa)
AEF81397.1Acyl-coenzyme A synthetase ACSM3; Identified by match to protein family HMM PF00501. (599 aa)
AEF83472.1Hypothetical protein; Identified by glimmer; putative. (502 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (194 aa)
AEF81482.1Conserved hypothetical protein. (190 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (357 aa)
pgkBifunctional PGK/TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (668 aa)
AEF82464.1H+-transporting two-sector ATPase, C subunit; Identified by match to protein family HMM PF00137. (105 aa)
atpA-3V-type sodium ATP synthase, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (602 aa)
atpB-3V-type sodium ATP synthase, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (474 aa)
atpD-2V-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa)
AEF81923.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. (470 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (368 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (611 aa)
Your Current Organism:
Treponema azotonutricium
NCBI taxonomy Id: 545695
Other names: T. azotonutricium ZAS-9, Treponema azotonutricium ZAS-9, Treponema azotonutricium str. ZAS-9, Treponema azotonutricium strain ZAS-9, Treponema sp. ZAS-9
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.