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fabH fabH fabD fabD fabG_2 fabG_2 fabF fabF AEF82996.1 AEF82996.1 fabV fabV accB accB AEF81971.1 AEF81971.1 accD accD accA accA AEF83090.1 AEF83090.1 AEF83263.1 AEF83263.1 AEF80396.1 AEF80396.1 AEF83018.1 AEF83018.1 AEF82896.1 AEF82896.1 AEF82669.1 AEF82669.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
fabH3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (341 aa)
fabD[acyl-carrier-protein] S-malonyltransferase; Identified by match to protein family HMM PF00698. (321 aa)
fabG_23-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (426 aa)
AEF82996.1Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Identified by match to protein family HMM PF07977. (142 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family. (422 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
AEF81971.1Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); Identified by match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786. (445 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (259 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (306 aa)
AEF83090.1long-chain-fatty-acid--CoA ligase; Identified by match to protein family HMM PF00501. (644 aa)
AEF83263.13-oxoacyl-[acyl-carrier-protein] reductase; Identified by match to protein family HMM PF00106. (251 aa)
AEF80396.1Chain N, Architecture Of Mammalian Fatty Acid Synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370. (245 aa)
AEF83018.1AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501. (577 aa)
AEF82896.1Putative long-chain-fatty-acid--CoA ligase; Identified by match to protein family HMM PF00501. (526 aa)
AEF82669.1AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501. (570 aa)
Your Current Organism:
Treponema azotonutricium
NCBI taxonomy Id: 545695
Other names: T. azotonutricium ZAS-9, Treponema azotonutricium ZAS-9, Treponema azotonutricium str. ZAS-9, Treponema azotonutricium strain ZAS-9, Treponema sp. ZAS-9
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