STRINGSTRING
EEF68426.1 EEF68426.1 aroB aroB aroC aroC aroK aroK EEF68432.1 EEF68432.1 EEF68158.1 EEF68158.1 EEF68159.1 EEF68159.1 aroQ aroQ EEF67721.1 EEF67721.1 dapB dapB EEF67672.1 EEF67672.1 dapD dapD asd asd EEF67196.1 EEF67196.1 dapA dapA EEF66284.1 EEF66284.1 thrB thrB thrC thrC EEF66287.1 EEF66287.1 EEF66288.1 EEF66288.1 asd-2 asd-2 EEF66078.1 EEF66078.1 EEF65740.1 EEF65740.1 EEF65600.1 EEF65600.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EEF68426.1KEGG: ttj:TTHA1104 1.1e-47 prephenate dehydratase K04518; Psort location: Cytoplasmic, score: 9.98. (281 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (334 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (397 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (410 aa)
EEF68432.1Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: cpe:CPE0694 1.8e-38 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; Psort location: Cytoplasmic, score: 8.87. (158 aa)
EEF68158.1Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (156 aa)
EEF68159.1KEGG: cno:NT01CX_0626 2.1e-51 prephenate dehydrogenase K00210; Psort location: Cytoplasmic, score: 8.87. (282 aa)
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (147 aa)
EEF67721.1Creatinase; KEGG: cpr:CPR_2506 2.1e-76 metallopeptidase, family M24 K01271; Psort location: Cytoplasmic, score: 8.87; Belongs to the peptidase M24B family. (351 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (256 aa)
EEF67672.1KEGG: cpe:CPE0698 7.6e-15 chorismate mutase K04516; Psort location: Cytoplasmic, score: 8.87. (143 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (232 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (333 aa)
EEF67196.1Putative 3-deoxy-7-phosphoheptulonate synthase; KEGG: cac:CAC0892 4.3e-37 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; Psort location: Cytoplasmic, score: 8.87. (158 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
EEF66284.1ACT domain protein; KEGG: ctc:CTC00116 4.7e-31 chorismate mutase K06209; Belongs to the UPF0735 family. (145 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (297 aa)
thrCThreonine synthase; KEGG: blo:BL1036 3.8e-107 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.87. (498 aa)
EEF66287.1KEGG: ldb:Ldb1350 5.3e-55 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87. (405 aa)
EEF66288.1Amino acid kinase family; KEGG: ldb:Ldb1349 2.8e-120 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family. (445 aa)
asd-2Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (334 aa)
EEF66078.1Amino acid kinase family; KEGG: bca:BCE_3837 3.1e-41 dapG; aspartate kinase I K00928; Psort location: Cytoplasmic, score: 8.87. (248 aa)
EEF65740.1Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (165 aa)
EEF65600.1EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: cpf:CPF_0689 2.1e-51 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800; Psort location: Cytoplasmic, score: 8.87. (293 aa)
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.