STRINGSTRING
metA metA cysK cysK AEB99581.1 AEB99581.1 thrC thrC AEB99803.1 AEB99803.1 dapA dapA dapB dapB asd asd AEC00145.1 AEC00145.1 thrB thrB AEC00198.1 AEC00198.1 AEC00213.1 AEC00213.1 metK metK AEC00732.1 AEC00732.1 serA serA serC serC patB patB AEC01153.1 AEC01153.1 AEC01214.1 AEC01214.1 AEC01231.1 AEC01231.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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metAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (311 aa)
cysKCOGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR001926:IPR005859; KEGG: elm:ELI_3635 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; IMG reference gene:2504585945; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
AEB99581.1COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: afn:Acfer_0064 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; IMG reference gene:2504586070; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (430 aa)
thrCCOGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: cth:Cthe_1381 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504586285; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (495 aa)
AEB99803.1COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: hmo:HM1_1450 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2504586312; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (248 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
AEC00145.1COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048:IPR002912:IPR005260; KEGG: vpr:Vpar_1126 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; IMG reference gene:2504586665; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (409 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
AEC00198.1COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR002912; KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504586719; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (440 aa)
AEC00213.1COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: ere:EUBREC_1577 serine acetyltransferase, plasmid; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; IMG reference gene:2504586734; TIGRFAM: serine O-acetyltransferase. (317 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
AEC00732.1COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: mpd:MCP_0979 putative threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; IMG reference gene:2504587267; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (331 aa)
serACOGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: pth:PTH_0012 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504587536; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hy [...] (527 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa)
patBCystathionine beta-lyase; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: elm:ELI_3637 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Cystathionine beta-lyase; SPTR: Hemolysin; IMG reference gene:2504587722; PFAM: Aminotransferase class I and II. (390 aa)
AEC01153.1Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: amt:Amet_3707 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Cystathionine beta-lyase; IMG reference gene:2504587724; PFAM: Cys/Met metabolism PLP-dependent enzyme. (379 aa)
AEC01214.1COGs: COG0620 Methionine synthase II (cobalamin-independent); InterPro IPR002629; KEGG: afn:Acfer_0167 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase, vitamin-B12 independent; SPTR: Vitamin-B12 independent methionine synthase family protein; IMG reference gene:2504587787; PFAM: Cobalamin-independent synthase, Catalytic domain. (372 aa)
AEC01231.1COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR006158:IPR003759:IPR003726:IPR000489; KEGG: hmo:HM1_2499 methionine synthase, putative; PFAM: Homocysteine S-methyltransferase; Cobalamin (vitamin B12)-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Pterin-binding; PRIAM: Methionine synthase; SPTR: Vitamin B12-dependent methionine synthase family protein; IMG reference gene:2504587804; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahyd [...] (790 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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