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mqnA mqnA thiD thiD AEB99250.1 AEB99250.1 mqnE mqnE hydG hydG thiS thiS thiG thiG thiH thiH AEB99427.1 AEB99427.1 thiC thiC AEC00334.1 AEC00334.1 AEC00335.1 AEC00335.1 AEC00336.1 AEC00336.1 AEC00543.1 AEC00543.1 AEC01032.1 AEC01032.1 AEC01162.1 AEC01162.1 AEC01163.1 AEC01163.1 mqnC mqnC mqnE-2 mqnE-2 AEC01167.1 AEC01167.1 AEC01168.1 AEC01168.1 AEC01169.1 AEC01169.1 AEC01170.1 AEC01170.1 AEC01171.1 AEC01171.1 AEC01172.1 AEC01172.1 AEC01173.1 AEC01173.1 AEC01175.1 AEC01175.1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (279 aa)
thiDPhosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: cac:CA_C3095 hydroxyethylthiazole kinase ThiM/ThiK; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; IMG reference gene:2504585474; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (263 aa)
AEB99250.1o-succinylbenzoate--CoA ligase; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0829 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: CoA ligase; IMG reference gene:2504585732; PFAM: AMP-binding enzyme; TIGRFAM: O-succinylbenzoate-CoA ligase. (492 aa)
mqnEPutative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (369 aa)
hydGBiotin and thiamin synthesis associated; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR010722:IPR007197; KEGG: elm:ELI_3377 thiamine biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Biotin/thiamin synthesis-associated protein; Elongator protein 3/MiaB/NifB; SPTR: Putative thiazole biosynthesis protein ThiH; IMG reference gene:2504585906; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. (474 aa)
thiSThiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: fsu:Fisuc_2908 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; IMG reference gene:2504585911; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (64 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (265 aa)
thiHCOGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR012726; KEGG: fsu:Fisuc_2911 thiamine biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Biotin/thiamin synthesis-associated protein; SPTR: Thiazole biosynthesis protein ThiH; TIGRFAM: Thiazole biosynthesis ThiH; IMG reference gene:2504585913; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH. (418 aa)
AEB99427.1COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: afn:Acfer_1200 thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate diphosphorylase; IMG reference gene:2504585914; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase. (199 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (435 aa)
AEC00334.1UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR007901:IPR000594; KEGG: ere:EUBREC_0899 hypothetical protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: Thiazole biosynthesis adenylyltransferase ThiF; IMG reference gene:2504586856; PFAM: MoeZ/MoeB domain; ThiF family. (261 aa)
AEC00335.1Hypothetical protein; SPTR: Putative ATP-dependent RNA helicase DDX6; IMG reference gene:2504586857. (100 aa)
AEC00336.1KEGG: afn:Acfer_0870 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586858. (168 aa)
AEC00543.1UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: thx:Thet_1429 UBA/ThiF-type NAD/FAD-binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: Hydrogenase accessory protein HypB; IMG reference gene:2504587072; PFAM: ThiF family. (246 aa)
AEC01032.1Thiamine-phosphate pyrophosphorylase; COGs: COG0352 Thiamine monophosphate synthase; HAMAP: Thiamine monophosphate synthase; InterPro IPR003733; KEGG: bad:BAD_1145 bifunctional protein thiEC; PFAM: Thiamine monophosphate synthase; PRIAM: Thiamine-phosphate diphosphorylase; SPTR: Thiamine-phosphate diphosphorylase; IMG reference gene:2504587600; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase. (240 aa)
AEC01162.1InterPro IPR003748; KEGG: dhd:Dhaf_2252 protein of unknown function DUF169; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein; IMG reference gene:2504587733; PFAM: Uncharacterised ArCR, COG2043. (239 aa)
AEC01163.1Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: dhd:Dhaf_2905 cation transporter; PFAM: Cation transporter; SPTR: Potassium uptake protein TrkH; IMG reference gene:2504587734; PFAM: Cation transport protein. (483 aa)
mqnCFO synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (346 aa)
mqnE-2FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (366 aa)
AEC01167.1KEGG: csh:Closa_3690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587738. (74 aa)
AEC01168.1KEGG: csh:Closa_3691 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587739. (79 aa)
AEC01169.1KEGG: csh:Closa_3692 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587740. (160 aa)
AEC01170.1Rhodanese-like protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: bpb:bpr_I2677 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504587741; PFAM: Rhodanese-like domain. (129 aa)
AEC01171.1SPTR: Putative uncharacterized protein; IMG reference gene:2504587742. (49 aa)
AEC01172.1SPTR: Putative uncharacterized protein; IMG reference gene:2504587743. (140 aa)
AEC01173.1SPTR: Putative uncharacterized protein; IMG reference gene:2504587744. (170 aa)
AEC01175.1SPTR: Putative uncharacterized protein; IMG reference gene:2504587746. (267 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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