STRINGSTRING
folE folE folP folP folB folB folK folK AEB99209.1 AEB99209.1 AEC00455.1 AEC00455.1 AEC00456.1 AEC00456.1 ribH ribH AEC00458.1 AEC00458.1 ribB ribB ribE ribE ribD ribD folB-2 folB-2 AEC00701.1 AEC00701.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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folECOGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602; KEGG: vpr:Vpar_0493 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; IMG reference gene:2504585685; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. (189 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (289 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: sga:GALLO_1229 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inediphosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504585688; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphok [...] (197 aa)
AEB99209.1KEGG: vcj:VCD_000991 hypothetical protein; SPTR: Procyclic form-specific polypeptide A-beta; IMG reference gene:2504585690. (289 aa)
AEC00455.1Protein of unknown function DUF2276; InterPro IPR019267; KEGG: vpr:Vpar_1811 hypothetical protein; PFAM: Protein of unknown function DUF2276; SPTR: Putative CRISPR-associated protein; IMG reference gene:2504586980; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated endoribonuclease Cas6. (267 aa)
AEC00456.1Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: tpd:Teth39_1576 phosphodiesterase; PFAM: Metallo-dependent phosphatase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Phosphodiesterase MJ0936; IMG reference gene:2504586981; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. (185 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa)
AEC00458.1ThiJ/PfpI domain-containing protein; InterPro IPR002818; KEGG: bfr:BF3075 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: DJ-1/PfpI family protein; manually curated; IMG reference gene:2504586983; PFAM: DJ-1/PfpI family. (204 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (404 aa)
ribECOGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (217 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
folB-2Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
AEC00701.1KEGG: adg:Adeg_1883 dihydropteroate synthase; SPTR: Dihydropteroate synthase; IMG reference gene:2504587235. (121 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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