node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB99041.1 | AEB99042.1 | Selsp_0059 | Selsp_0060 | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | 0.980 |
AEB99041.1 | fmt | Selsp_0059 | Selsp_1105 | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.914 |
AEB99041.1 | glyA | Selsp_0059 | Selsp_0027 | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
AEB99041.1 | glyA-2 | Selsp_0059 | Selsp_1925 | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase. | 0.904 |
AEB99041.1 | purN | Selsp_0059 | Selsp_1017 | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.910 |
AEB99042.1 | AEB99041.1 | Selsp_0060 | Selsp_0059 | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | 0.980 |
AEB99042.1 | fmt | Selsp_0060 | Selsp_1105 | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.900 |
AEB99042.1 | glyA | Selsp_0060 | Selsp_0027 | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
AEB99042.1 | glyA-2 | Selsp_0060 | Selsp_1925 | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase. | 0.904 |
AEB99042.1 | purN | Selsp_0060 | Selsp_1017 | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.910 |
AEB99978.1 | AEC01233.1 | Selsp_1018 | Selsp_2289 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. | 0.947 |
AEB99978.1 | glyA | Selsp_1018 | Selsp_0027 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.701 |
AEB99978.1 | glyA-2 | Selsp_1018 | Selsp_1925 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. | COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase. | 0.637 |
AEB99978.1 | purN | Selsp_1018 | Selsp_1017 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.994 |
AEC01233.1 | AEB99978.1 | Selsp_2289 | Selsp_1018 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. | 0.947 |
AEC01233.1 | glyA | Selsp_2289 | Selsp_0027 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.968 |
AEC01233.1 | glyA-2 | Selsp_2289 | Selsp_1925 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. | COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase. | 0.962 |
AEC01233.1 | purN | Selsp_2289 | Selsp_1017 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.997 |
fmt | AEB99041.1 | Selsp_1105 | Selsp_0059 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | methionyl-tRNA formyltransferase-like protein; COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase. | 0.914 |
fmt | AEB99042.1 | Selsp_1105 | Selsp_0060 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase. | 0.900 |