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argH argH dapA dapA aroF-2 aroF-2 nth nth AEB99949.1 AEB99949.1 pyrF pyrF cobD cobD AEB99797.1 AEB99797.1 rfbB rfbB pckA pckA thrC thrC AEB99781.1 AEB99781.1 ispF ispF moaC moaC moaA moaA thiC thiC AEB99511.1 AEB99511.1 gcdC gcdC mmdA mmdA mce mce aroF aroF AEB99463.1 AEB99463.1 fumC fumC panD panD AEB99344.1 AEB99344.1 AEB99337.1 AEB99337.1 cobA cobA hemB hemB aepX aepX cah cah eno eno folB folB AEB99164.1 AEB99164.1 gmd gmd AEB99027.1 AEB99027.1 deoC deoC mqnA mqnA ilvA ilvA purB purB AEC01182.1 AEC01182.1 AEC01131.1 AEC01131.1 AEC01109.1 AEC01109.1 lysA lysA AEC00990.1 AEC00990.1 fabZ fabZ aroC aroC aroB aroB trpC trpC trpA trpA AEC00703.1 AEC00703.1 folB-2 folB-2 cbiK-3 cbiK-3 AEC00586.1 AEC00586.1 AEC00585.1 AEC00585.1 coaBC coaBC dacA dacA cbiK-2 cbiK-2 AEC00561.1 AEC00561.1 gcdB gcdB trpB trpB ribB ribB AEC00458.1 AEC00458.1 AEC00351.1 AEC00351.1 speD-2 speD-2 nspC nspC leuC leuC leuD leuD AEC00148.1 AEC00148.1 fba fba ilvD ilvD psd psd queD queD queE queE hisF hisF hisH hisH hisB hisB AEC00063.1 AEC00063.1 mutM mutM murQ murQ mltG mltG speD speD AEB99998.1 AEB99998.1
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argHCOGs: COG0165 Argininosuccinate lyase; InterPro IPR022761:IPR009049; KEGG: vpr:Vpar_1567 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504586514; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (475 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
aroF-2Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504586473; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (337 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (209 aa)
AEB99949.1COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379; KEGG: tit:Thit_1131 conserved carboxylase region; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: Oxaloacetate decarboxylase alpha subunit; IMG reference gene:2504586467; PFAM: HMGL-like; Conserved carboxylase domain. (464 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (239 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
AEB99797.1Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: chy:CHY_1808 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: Menaquinone biosynthesis decarboxylase, SCO4490 family; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504586306; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; menaquinone biosynthesis decarboxylase, SCO4490 family; Belongs t [...] (486 aa)
rfbBdTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: afn:Acfer_0578 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2504586291; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
thrCCOGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: cth:Cthe_1381 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504586285; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (495 aa)
AEB99781.1ybaK/ebsC protein; COGs: COG2606 conserved hypothetical protein; InterPro IPR007214:IPR004369; KEGG: sus:Acid_5432 YbaK/EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase-associated domain; SPTR: YbaK/ebsC protein; TIGRFAM: Prolyl-tRNA editing protein, YbaK/EbsC; IMG reference gene:2504586284; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein. (185 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (161 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (328 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (435 aa)
AEB99511.1COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: glo:Glov_0789 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; IMG reference gene:2504585998; PFAM: 3-dehydroquinate synthase. (357 aa)
gcdCCOGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR000089; KEGG: aoe:Clos_0442 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; SPTR: Methylmalonyl-CoA decarboxylase, gamma subunit; IMG reference gene:2504585967; PFAM: Biotin-requiring enzyme. (128 aa)
mmdACOGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: vpr:Vpar_1244 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase, beta subunit; IMG reference gene:2504585965; PFAM: Carboxyl transferase domain; TIGRFAM: methylmalonyl-CoA decarboxylase alpha subunit. (509 aa)
mcemethylmalonyl-CoA epimerase; InterPro IPR004360:IPR017515; KEGG: vpr:Vpar_1245 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504585964; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. (140 aa)
aroFPhospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504585951; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (343 aa)
AEB99463.1COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Chorismate mutase/prephenate dehydratase; IMG reference gene:2504585950; PFAM: Prephenate dehydratase; ACT domain. (296 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
AEB99344.1Aromatic amino acid beta-eliminating lyase/threonine aldolase; COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bad:BAD_0527 low specificity-threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; SPTR: Low specificity L-threonine aldolase; IMG reference gene:2504585830; PFAM: Beta-eliminating lyase. (347 aa)
AEB99337.1COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367:IPR019478; KEGG: adg:Adeg_1261 siroheme synthase; PFAM: Sirohaem synthase, dimerisation domain; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal; IMG reference gene:2504585823; PFAM: Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain. (217 aa)
cobAuroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003754:IPR006366:IPR000878; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; Tetrapyrrole methylase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504585820; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-II [...] (503 aa)
hemBPorphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: vpr:Vpar_1423 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; IMG reference gene:2504585819; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (324 aa)
aepXPhosphoenolpyruvate phosphomutase; COGs: COG2513 PEP phosphonomutase; InterPro IPR004821:IPR004820:IPR012698; KEGG: ols:Olsu_0594 phosphoenolpyruvate phosphomutase; PFAM: Cytidylyltransferase; PRIAM: Phosphoenolpyruvate mutase; SPTR: Phosphoenolpyruvate mutase; TIGRFAM: Phosphoenolpyruvate phosphomutase, core; Cytidyltransferase-related; IMG reference gene:2504585796; PFAM: Cytidylyltransferase; TIGRFAM: phosphoenolpyruvate phosphomutase; cytidyltransferase-related domain. (433 aa)
cahCarbonate dehydratase; COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: vpr:Vpar_1311 carbonic anhydrase; PFAM: Carbonic anhydrase; PRIAM: Carbonate dehydratase; SMART: Carbonic anhydrase; SPTR: Carbonate dehydratase; IMG reference gene:2504585768; PFAM: Carbonic anhydrase. (187 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
AEB99164.1COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR022761:IPR018951; KEGG: vpr:Vpar_1504 fumarate lyase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal; PRIAM: Aspartate ammonia-lyase; SPTR: Aspartate ammonia-lyase; IMG reference gene:2504585641; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase. (463 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa)
AEB99027.1GDP-mannose 4,6-dehydratase; COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509; KEGG: gur:Gura_3780 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; IMG reference gene:2504585495; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase. (327 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (214 aa)
mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (279 aa)
ilvACOGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR005789; KEGG: clj:CLJU_c15090 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; IMG reference gene:2504587795; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form. (415 aa)
purBCOGs: COG0015 Adenylosuccinate lyase; InterPro IPR022761:IPR004769:IPR019468; KEGG: bhy:BHWA1_00426 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504587766; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (430 aa)
AEC01182.1InterPro IPR004360; KEGG: etr:ETAE_1244 glyoxalase/bleomycin resistance; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase family protein; IMG reference gene:2504587753; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (127 aa)
AEC01131.1Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR006250:IPR001030:IPR000573; KEGG: tjr:TherJR_2355 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Putative aconitate hydratase; TIGRFAM: Aconitase, putative; IMG reference gene:2504587702; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type. (644 aa)
AEC01109.1KEGG: elm:ELI_2754 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587679. (218 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa)
AEC00990.1InterPro IPR004360; KEGG: afn:Acfer_0826 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase; IMG reference gene:2504587556; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: lactoylglutathione lyase. (121 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (147 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (384 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (365 aa)
trpCCOGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: gme:Gmet_2494 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; IMG reference gene:2504587241; PFAM: Indole-3-glycerol phosphate synthase. (266 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
AEC00703.1Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: nla:NLA_12940 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; IMG reference gene:2504587237; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (189 aa)
folB-2Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
cbiK-3Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: vpr:Vpar_1135 anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Cobalt chelatase; IMG reference gene:2504587156; PFAM: Cobalt chelatase (CbiK). (314 aa)
AEC00586.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: vpr:Vpar_1529 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; IMG reference gene:2504587118; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tart [...] (280 aa)
AEC00585.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: vpr:Vpar_1528 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; IMG reference gene:2504587117; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate s [...] (185 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
dacAConserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (277 aa)
cbiK-2Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: ssm:Spirs_0173 sirohydrochlorin cobaltochelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative cobalt chelatase; IMG reference gene:2504587091; PFAM: Cobalt chelatase (CbiK). (264 aa)
AEC00561.1InterPro IPR005899; KEGG: vpr:Vpar_1243 sodium pump decarboxylase, gamma subunit; PFAM: Sodium ion-translocating decarboxylase; SPTR: Glutaconyl-CoA decarboxylase subunit delta; IMG reference gene:2504587090; PFAM: Oxaloacetate decarboxylase, gamma chain. (112 aa)
gcdBSodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (378 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (404 aa)
AEC00458.1ThiJ/PfpI domain-containing protein; InterPro IPR002818; KEGG: bfr:BF3075 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: DJ-1/PfpI family protein; manually curated; IMG reference gene:2504586983; PFAM: DJ-1/PfpI family. (204 aa)
AEC00351.1UPF0272 protein; COGs: COG1641 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0272; InterPro IPR002822; KEGG: cac:CA_C0774 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: Hypothetical cytosolic protein; TIGRFAM: Uncharacterised protein family UPF0272; IMG reference gene:2504586873; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein. (424 aa)
speD-2S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (257 aa)
nspCCOGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR005730:IPR022643; KEGG: bha:BH3958 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, C-terminal; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase; IMG reference gene:2504586738; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase. (387 aa)
leuCHomoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
AEC00148.1Fructose-bisphosphate aldolase class-I; COGs: COG3588 Fructose-1 6-bisphosphate aldolase; InterPro IPR000741; KEGG: fjo:Fjoh_0953 fructose-1,6-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase, class-I; SPTR: Fructose-bisphosphate aldolase class-I; IMG reference gene:2504586668; PFAM: Fructose-bisphosphate aldolase class-I. (295 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: cce:Ccel_2222 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504586667; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, [...] (329 aa)
ilvDCOGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: afn:Acfer_1425 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504586638; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (550 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (217 aa)
queDQueuosine biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: drm:Dred_1754 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Queuosine biosynthesis protein QueD; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504586623; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (125 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (241 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa)
hisBCOGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: cth:Cthe_2884 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; IMG reference gene:2504586612; PFAM: Imidazoleglycerol-phosphate dehydratase. (194 aa)
AEC00063.1COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: afn:Acfer_0383 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase family protein; IMG reference gene:2504586583; PFAM: Amidohydrolase. (270 aa)
mutMformamidopyrimidine-DNA glycosylase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the FPG family. (477 aa)
murQGlucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (301 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (415 aa)
speDS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. (155 aa)
AEB99998.1CoA-substrate-specific enzyme activase; COGs: COG3581 conserved hypothetical protein; InterPro IPR018709:IPR008275:IPR010327:IPR002731; KEGG: ccv:CCV52592_1797 CoA-substrate-specific enzyme activase domain-containing protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; 2-hydroxyglutaryl-CoA dehydratase, D-component; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: BadF/BadG/BcrA/BcrD ATPase family protein; TIGRFAM: CoA enzyme activase; IMG reference gene:2504586518; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase u [...] (1417 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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