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aroE aroE gap gap dapB dapB asd asd AEC00176.1 AEC00176.1 ilvC ilvC AEC00198.1 AEC00198.1 dxr dxr ribD ribD AEC00616.1 AEC00616.1 AEB99027.1 AEB99027.1 gmd gmd hemA hemA AEB99348.1 AEB99348.1 proA proA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa)
gapCOGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bpb:bpr_I2050 glyceraldehyde-3-phosphate dehydrogenase Gap; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG refer [...] (337 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
AEC00176.1C_GCAxxG_C_C family protein; InterPro IPR010181; KEGG: eel:EUBELI_20402 hypothetical protein; PFAM: CGCAxxGCC motif; SPTR: Redox family protein; IMG reference gene:2504586696; PFAM: Putative redox-active protein (C_GCAxxG_C_C). (131 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
AEC00198.1COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR002912; KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504586719; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (440 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
AEC00616.12-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: gwc:GWCH70_0924 6-phosphogluconate dehydrogenase NAD-binding; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; IMG reference gene:2504587148; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. (289 aa)
AEB99027.1GDP-mannose 4,6-dehydratase; COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509; KEGG: gur:Gura_3780 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; IMG reference gene:2504585495; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase. (327 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (439 aa)
AEB99348.1Transcriptional repressor, CtsR; COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: ppm:PPSC2_c4814 transcriptional repressor; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcriptional regulator CtsR; IMG reference gene:2504585835; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR). (194 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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