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AEC01104.1 | COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sss:SSUSC84_0203 putative oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; SPTR: Oxidoreductase, Gfo/Idh/MocA family; IMG reference gene:2504587673; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (333 aa) | ||||
AEC01117.1 | Putative phytochrome sensor protein; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR003018; KEGG: bbe:BBR47_05560 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SMART: GAF; SPTR: Putative GAF domain protein; IMG reference gene:2504587687; PFAM: NAD dependent epimerase/dehydratase family. (711 aa) | ||||
AEC01149.1 | TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dhd:Dhaf_2907 potassium transporter peripheral membrane component; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Trk system potassium uptake protein TrkA 1; IMG reference gene:2504587720; PFAM: TrkA-N domain; TrkA-C domain. (448 aa) | ||||
folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) | ||||
proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (265 aa) | ||||
AEB99845.1 | 3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: vpr:Vpar_0426 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Cyclopentanol dehydrogenase; IMG reference gene:2504586354; PFAM: short chain dehydrogenase. (250 aa) | ||||
AEB99956.1 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: gur:Gura_1463 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504586474; PFAM: Prephenate dehydrogenase. (293 aa) | ||||
argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa) | ||||
dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) | ||||
ahcY | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (413 aa) | ||||
pdxB | COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: cbe:Cbei_4594 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Glycerate dehydrogenase; IMG reference gene:2504586661; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (313 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) | ||||
AEC00198.1 | COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR002912; KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504586719; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (440 aa) | ||||
LYS1 | COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: bha:BH3957 hypothetical protein; PFAM: Saccharopine dehydrogenase / Homospermidine synthase; SPTR: Saccharopine dehydrogenase; IMG reference gene:2504586739; PFAM: Saccharopine dehydrogenase. (399 aa) | ||||
dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa) | ||||
sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa) | ||||
AEC00612.1 | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (322 aa) | ||||
AEC00616.1 | 2-hydroxy-3-oxopropionate reductase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: gwc:GWCH70_0924 6-phosphogluconate dehydrogenase NAD-binding; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; IMG reference gene:2504587148; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. (289 aa) | ||||
fabG | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) | ||||
aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa) | ||||
galE | COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: cbe:Cbei_4420 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; IMG reference gene:2504587371; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa) | ||||
AEC00898.1 | TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006037:IPR003148; KEGG: eel:EUBELI_20168 trk system potassium uptake protein TrkA; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Potassium uptake protein KtrA; IMG reference gene:2504587440; PFAM: TrkA-N domain; TrkA-C domain. (217 aa) | ||||
serA | COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: pth:PTH_0012 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504587536; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hy [...] (527 aa) | ||||
gap | COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bpb:bpr_I2050 glyceraldehyde-3-phosphate dehydrogenase Gap; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG refer [...] (337 aa) | ||||
pdxB-2 | Glyoxylate reductase (NADP(+)); COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: afn:Acfer_1520 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Glyoxylate reductase (NADP(+)); SPTR: Dehydrogenase; IMG reference gene:2504587658; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (317 aa) | ||||
rfbB | dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: afn:Acfer_0578 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2504586291; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa) | ||||
AEB99583.1 | 2-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR003710:IPR013332:IPR013752; KEGG: swo:Swol_1181 putative oxidoreductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal; Ketopantoate reductase ApbA/PanE, C-terminal; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; IMG reference gene:2504586072; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase. (308 aa) | ||||
AEB99513.1 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: vpa:VP1321 putative dTDP-glucose 4-6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative nucleotide sugar dehydratase; IMG reference gene:2504586000; PFAM: NAD dependent epimerase/dehydratase family. (370 aa) | ||||
AEB99508.1 | 3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: nmr:Nmar_0026 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinC; IMG reference gene:2504585995; PFAM: short chain dehydrogenase. (246 aa) | ||||
AEB99408.1 | L-iditol 2-dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013149:IPR013154; KEGG: sea:SeAg_B4593 oxidoreductase, zinc-binding dehydrogenase family; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: L-iditol 2-dehydrogenase; SPTR: Putative L-iditol 2-dehydrogenase; IMG reference gene:2504585895; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (350 aa) | ||||
hldD | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (323 aa) | ||||
AEB99338.1 | COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006096:IPR006097; KEGG: cpf:CPF_1770 glutamate dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: Glutamate dehydrogenase (NADP(+)); SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: Glutamate dehydrogenase, NADP-specific; IMG reference gene:2504585824; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belong [...] (449 aa) | ||||
hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (439 aa) | ||||
rfbG | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR013445; KEGG: csh:Closa_0495 CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: CDP-glucose 4,6-dehydratase; SPTR: CDP-glucose 4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; IMG reference gene:2504585806; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. (362 aa) | ||||
AEB99175.1 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (326 aa) | ||||
AEB99155.1 | Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR014027:IPR001732:IPR014026; KEGG: cth:Cthe_2340 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose/GDP-mannose dehydrogenase family protein; TIGRFAM: Nucleotide sugar dehydrogenase; IMG reference gene:2504585632; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD bind [...] (433 aa) | ||||
AEB99116.1 | UDP-glucose 4-epimerase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: hmo:HM1_1189 nad-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; IMG reference gene:2504585590; PFAM: NAD dependent epimerase/dehydratase family. (310 aa) | ||||
rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (279 aa) | ||||
pseB | UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: rpf:Rpic12D_0580 polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: UDP-N-acetylglucosamine 4,6-dehydratase; TIGRFAM: Pseudaminic acid biosynthesis, PseB; IMG reference gene:2504585504; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase. (327 aa) | ||||
fcl | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (313 aa) | ||||
gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa) | ||||
AEB99027.1 | GDP-mannose 4,6-dehydratase; COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509; KEGG: gur:Gura_3780 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; IMG reference gene:2504585495; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase. (327 aa) |