node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ribB | ribD | Selsp_1502 | Selsp_1504 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ribB | ribE | Selsp_1502 | Selsp_1503 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.999 |
ribB | ribF | Selsp_1502 | Selsp_1148 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 0.662 |
ribB | ribH | Selsp_1502 | Selsp_1500 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribD | ribB | Selsp_1504 | Selsp_1502 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
ribD | ribE | Selsp_1504 | Selsp_1503 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.998 |
ribD | ribF | Selsp_1504 | Selsp_1148 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 0.406 |
ribD | ribH | Selsp_1504 | Selsp_1500 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.968 |
ribE | ribB | Selsp_1503 | Selsp_1502 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
ribE | ribD | Selsp_1503 | Selsp_1504 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.998 |
ribE | ribF | Selsp_1503 | Selsp_1148 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 0.938 |
ribE | ribH | Selsp_1503 | Selsp_1500 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribF | ribB | Selsp_1148 | Selsp_1502 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.662 |
ribF | ribD | Selsp_1148 | Selsp_1504 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.406 |
ribF | ribE | Selsp_1148 | Selsp_1503 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.938 |
ribF | ribH | Selsp_1148 | Selsp_1500 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.823 |
ribH | ribB | Selsp_1500 | Selsp_1502 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
ribH | ribD | Selsp_1500 | Selsp_1504 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.968 |
ribH | ribE | Selsp_1500 | Selsp_1503 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.999 |
ribH | ribF | Selsp_1500 | Selsp_1148 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 0.823 |