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AEB99039.1 AEB99039.1 gltX gltX hemL hemL hemB hemB cobA cobA hemC hemC hemA hemA AEB99337.1 AEB99337.1 hemZ hemZ cobI cobI cbiD cbiD cbiE cbiE cbiT cbiT cobM cobM AEB99886.1 AEB99886.1 cobJ cobJ cobK cobK cobH cobH cobB cobB AEB99891.1 AEB99891.1 cobQ cobQ cobD cobD cobS cobS AEB99895.1 AEB99895.1 AEB99896.1 AEB99896.1 cobO cobO AEC00166.1 AEC00166.1 AEC00167.1 AEC00167.1 AEC00168.1 AEC00168.1 AEC00169.1 AEC00169.1 AEC00193.1 AEC00193.1 AEC00260.1 AEC00260.1 cbiK cbiK AEC00497.1 AEC00497.1 AEC00537.1 AEC00537.1 cbiK-2 cbiK-2 cbiK-3 cbiK-3 AEC00719.1 AEC00719.1 AEC00724.1 AEC00724.1 AEC00725.1 AEC00725.1 cobT cobT
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AEB99039.1COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: cts:Ctha_2091 aminotransferase class-III; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; IMG reference gene:2504585508; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (486 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR004639:IPR005814; KEGG: mta:Moth_1244 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; IMG reference gene:2504585818; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (438 aa)
hemBPorphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: vpr:Vpar_1423 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; IMG reference gene:2504585819; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (324 aa)
cobAuroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003754:IPR006366:IPR000878; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; Tetrapyrrole methylase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504585820; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-II [...] (503 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (439 aa)
AEB99337.1COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367:IPR019478; KEGG: adg:Adeg_1261 siroheme synthase; PFAM: Sirohaem synthase, dimerisation domain; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal; IMG reference gene:2504585823; PFAM: Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain. (217 aa)
hemZCOGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cth:Cthe_1341 coproporphyrinogen III oxidase; PFAM: Radical SAM; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen oxidase, anaerobic; IMG reference gene:2504586229; PFAM: Radical SAM superfamily; TIGRFAM: coproporphyrinogen dehydrogenase HemZ. (508 aa)
cobICOGs: COG2243 Precorrin-2 methylase; InterPro IPR006364:IPR000878; KEGG: vpr:Vpar_1130 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-2 C(20)-methyltransferase; SPTR: Precorrin-2 C(20)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; IMG reference gene:2504586366; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase. (233 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (367 aa)
cbiEPrecorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR000878:IPR012818; KEGG: vpr:Vpar_1145 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; manually curated; IMG reference gene:2504586392; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), Cb [...] (208 aa)
cbiTprecorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR003682:IPR014008; KEGG: has:Halsa_2200 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: rRNA small subunit methyltransferase G; SPTR: Precorrin-6y c5,15-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504586393; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit. (195 aa)
cobMCOGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: vpr:Vpar_1143 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504586394; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase. (252 aa)
AEB99886.1COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR021744:IPR002750; KEGG: aar:Acear_0836 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin synthesis G N-terminal; Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: CbiG protein; IMG reference gene:2504586395; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal. (350 aa)
cobJCOGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR000878; KEGG: vpr:Vpar_1141 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504586396; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. (246 aa)
cobKCOGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: vpr:Vpar_1140 precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; SPTR: Precorrin-6x reductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; IMG reference gene:2504586397; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase. (254 aa)
cobHPrecorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: vpr:Vpar_1139 precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase; IMG reference gene:2504586398; PFAM: Precorrin-8X methylmutase. (210 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (468 aa)
AEB99891.1COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: rrs:RoseRS_0575 adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobalamin biosynthesis protein CobU; IMG reference gene:2504586400; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase. (185 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (511 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (275 aa)
AEB99895.1L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839; KEGG: tjr:TherJR_1312 L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII; SPTR: Threonine-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; manually curated; IMG reference gene:2504586404; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. (357 aa)
AEB99896.1Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: drm:Dred_1908 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Phosphoglycerate mutase family protein; IMG reference gene:2504586405; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase. (209 aa)
cobOCOGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: chy:CHY_2619 cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; IMG reference gene:2504586639; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase. (179 aa)
AEC00166.1Cobaltochelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: vpr:Vpar_0072 CobN/magnesium chelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: Cobaltochelatase, CobN subunit; IMG reference gene:2504586686; PFAM: CobN/Magnesium Chelatase; TIGRFAM: magnesium chelatase, H subunit; cobaltochelatase, CobN subunit. (1230 aa)
AEC00167.1Protein of unknown function DUF105; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808; KEGG: tjr:TherJR_1261 protein of unknown function DUF105; PFAM: Adenosylcobinamide amidohydrolase, CbiZ; SPTR: Putative adenosylcobinamide amidohydrolase; IMG reference gene:2504586687; PFAM: Adenosylcobinamide amidohydrolase. (370 aa)
AEC00168.1COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR002035; KEGG: dsy:DSY3869 hypothetical protein; PFAM: von Willebrand factor, type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor, type A; SPTR: Magnesium-chelatase, subunit D/I family; IMG reference gene:2504586688; PFAM: von Willebrand factor type A domain; AAA domain (dynein-related subfamily). (648 aa)
AEC00169.1COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593; KEGG: aoe:Clos_2327 magnesium chelatase; PRIAM: Magnesium chelatase; SMART: ATPase, AAA+ type, core; SPTR: Magnesium chelatase, ATPase subunit I; IMG reference gene:2504586689; PFAM: Magnesium chelatase, subunit ChlI. (339 aa)
AEC00193.1ATP/cobalamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR002779; KEGG: vpr:Vpar_0903 ATP/cobalamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; SPTR: ATP:cob(I)alamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal; IMG reference gene:2504586714; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase. (166 aa)
AEC00260.1Putative transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: nth:Nther_1129 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Putative NirD protein; IMG reference gene:2504586781. (150 aa)
cbiKSirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: vpr:Vpar_1135 anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Cobalt chelatase; IMG reference gene:2504586897; PFAM: Cobalt chelatase (CbiK). (332 aa)
AEC00497.1Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cpy:Cphy_3574 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative radical SAM domain protein; IMG reference gene:2504587025; PFAM: Radical SAM superfamily. (590 aa)
AEC00537.1COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: vpr:Vpar_1843 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; IMG reference gene:2504587066; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase. (190 aa)
cbiK-2Anaerobic cobalt chelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: ssm:Spirs_0173 sirohydrochlorin cobaltochelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative cobalt chelatase; IMG reference gene:2504587091; PFAM: Cobalt chelatase (CbiK). (264 aa)
cbiK-3Sirohydrochlorin cobaltochelatase; COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: vpr:Vpar_1135 anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Cobalt chelatase; IMG reference gene:2504587156; PFAM: Cobalt chelatase (CbiK). (314 aa)
AEC00719.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (385 aa)
AEC00724.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3350 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504587258; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain. (330 aa)
AEC00725.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3352 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Nitrite reductase heme biosynthesis J protein; IMG reference gene:2504587259; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain. (398 aa)
cobTNicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (679 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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