STRINGSTRING
mqnA mqnA glyA glyA AEB99039.1 AEB99039.1 AEB99045.1 AEB99045.1 rfbD rfbD gltX gltX pfkA pfkA AEB99175.1 AEB99175.1 manA manA fbp fbp AEB99230.1 AEB99230.1 eno eno hisC hisC mqnE mqnE aepX aepX hemL hemL hemB hemB cobA cobA hemC hemC hemA hemA AEB99337.1 AEB99337.1 dapF dapF AEB99344.1 AEB99344.1 panD panD panC panC metA metA ilvB ilvB ilvN ilvN fumC fumC cysK cysK AEB99463.1 AEB99463.1 aroF aroF AEB99473.1 AEB99473.1 purF purF AEB99509.1 AEB99509.1 AEB99511.1 AEB99511.1 aepY aepY AEB99583.1 AEB99583.1 AEB99584.1 AEB99584.1 AEB99686.1 AEB99686.1 AEB99692.1 AEB99692.1 proB proB proA proA AEB99717.1 AEB99717.1 hemZ hemZ ispD ispD ispF ispF aroH aroH thrC thrC pckA pckA rfbA rfbA rfbC rfbC rfbB rfbB deoD deoD AEB99793.1 AEB99793.1 AEB99797.1 AEB99797.1 AEB99798.1 AEB99798.1 gltA gltA proC proC hpt hpt AEB99910.1 AEB99910.1 AEB99954.1 AEB99954.1 aroF-2 aroF-2 AEB99956.1 AEB99956.1 AEB99960.1 AEB99960.1 purE purE purC purC purM purM purN purN purD purD dapA dapA argC argC argJ argJ argB argB argD argD argF argF argG argG argH argH dapB dapB asd asd aroQ aroQ AEC00031.1 AEC00031.1 dxs dxs rpe rpe hisZ hisZ hisG hisG hisD hisD hisB hisB hisH hisH hisA hisA hisF hisF hisE hisE pssA pssA psd psd ribF ribF ilvD ilvD surE surE tkt tkt AEC00144.1 AEC00144.1 AEC00145.1 AEC00145.1 fba fba AEC00148.1 AEC00148.1 AEC00168.1 AEC00168.1 AEC00169.1 AEC00169.1 AEC00179.1 AEC00179.1 AEC00181.1 AEC00181.1 ilvB-2 ilvB-2 leuB leuB leuD leuD leuC leuC ilvC ilvC ilvN-2 ilvN-2 ndk ndk thrB thrB AEC00198.1 AEC00198.1 pheB pheB plsY plsY ispH ispH AEC00205.1 AEC00205.1 aroA aroA AEC00213.1 AEC00213.1 LYS1 LYS1 miaA miaA pfp pfp AEC00258.1 AEC00258.1 AEC00260.1 AEC00260.1 leuA leuA ispG ispG dxr dxr cdsA cdsA uppS uppS ilvE ilvE adk adk ribH ribH ribB ribB ribE ribE ribD ribD trpB trpB AEC00473.1 AEC00473.1 sucD sucD sucC sucC AEC00497.1 AEC00497.1 AEC00525.1 AEC00525.1 AEC00548.1 AEC00548.1 nifJ nifJ AEC00572.1 AEC00572.1 metK metK sdhB sdhB sdhA sdhA sdhC sdhC AEC00585.1 AEC00585.1 AEC00586.1 AEC00586.1 prs prs ispE ispE AEC00612.1 AEC00612.1 acpP acpP fabG fabG fabD fabD plsX plsX AEC00703.1 AEC00703.1 trpE trpE trpA trpA trpB-2 trpB-2 trpC trpC trpF trpF AEC00719.1 AEC00719.1 AEC00722.1 AEC00722.1 AEC00724.1 AEC00724.1 AEC00725.1 AEC00725.1 AEC00732.1 AEC00732.1 AEC00733.1 AEC00733.1 aroB aroB aroK aroK aroC aroC aroE aroE trpD trpD AEC00839.1 AEC00839.1 AEC00841.1 AEC00841.1 glpA glpA glpB glpB glpC glpC glyA-2 glyA-2 AEC00882.1 AEC00882.1 pgi pgi galU galU AEC00910.1 AEC00910.1 AEC00943.1 AEC00943.1 AEC00963.1 AEC00963.1 serA serA serC serC glgA glgA glgB glgB glgP glgP glgD glgD glgC glgC lysA lysA AEC01002.1 AEC01002.1 AEC01005.1 AEC01005.1 gpmI gpmI tpiA tpiA pgk pgk gap gap AEC01058.1 AEC01058.1 AEC01131.1 AEC01131.1 AEC01132.1 AEC01132.1 AEC01133.1 AEC01133.1 pyk pyk patB patB AEC01153.1 AEC01153.1 mqnC mqnC mqnE-2 mqnE-2 AEC01189.1 AEC01189.1 AEC01190.1 AEC01190.1 purB purB AEC01214.1 AEC01214.1 ilvA ilvA AEC01231.1 AEC01231.1 pfkA-2 pfkA-2 AEC01233.1 AEC01233.1
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mqnAProtein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (279 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AEB99039.1COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: cts:Ctha_2091 aminotransferase class-III; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; IMG reference gene:2504585508; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
AEB99045.1COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR013096; KEGG: bpb:bpr_I2267 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; PFAM: Nucleotidyl transferase; Cupin 2, conserved barrel; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-6-phosphate isomerase mannose-1-phosphate guanylyl transferase; IMG reference gene:2504585515; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. (437 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (279 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (486 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
AEB99175.1Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (326 aa)
manAMannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: cce:Ccel_1179 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504585676; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I. (325 aa)
fbpFructose-1,6-bisphosphatase class 3; COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: ols:Olsu_1042 fructose-16-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 3; IMG reference gene:2504585679; PFAM: Firmicute fructose-1,6-bisphosphatase. (649 aa)
AEB99230.1Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: cpe:CPE2104 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Putative membrane protein; IMG reference gene:2504585711; PFAM: Heptaprenyl diphosphate synthase component I. (221 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
hisCCOGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861; KEGG: eel:EUBELI_00629 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase; IMG reference gene:2504585758; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransfer [...] (350 aa)
mqnEPutative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (369 aa)
aepXPhosphoenolpyruvate phosphomutase; COGs: COG2513 PEP phosphonomutase; InterPro IPR004821:IPR004820:IPR012698; KEGG: ols:Olsu_0594 phosphoenolpyruvate phosphomutase; PFAM: Cytidylyltransferase; PRIAM: Phosphoenolpyruvate mutase; SPTR: Phosphoenolpyruvate mutase; TIGRFAM: Phosphoenolpyruvate phosphomutase, core; Cytidyltransferase-related; IMG reference gene:2504585796; PFAM: Cytidylyltransferase; TIGRFAM: phosphoenolpyruvate phosphomutase; cytidyltransferase-related domain. (433 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR004639:IPR005814; KEGG: mta:Moth_1244 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; IMG reference gene:2504585818; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (438 aa)
hemBPorphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: vpr:Vpar_1423 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; IMG reference gene:2504585819; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (324 aa)
cobAuroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003754:IPR006366:IPR000878; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; Tetrapyrrole methylase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504585820; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-II [...] (503 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (439 aa)
AEB99337.1COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367:IPR019478; KEGG: adg:Adeg_1261 siroheme synthase; PFAM: Sirohaem synthase, dimerisation domain; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal; IMG reference gene:2504585823; PFAM: Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain. (217 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa)
AEB99344.1Aromatic amino acid beta-eliminating lyase/threonine aldolase; COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bad:BAD_0527 low specificity-threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; SPTR: Low specificity L-threonine aldolase; IMG reference gene:2504585830; PFAM: Beta-eliminating lyase. (347 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (286 aa)
metAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (311 aa)
ilvBAcetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: dhd:Dhaf_3617 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504585902; PFAM: Thiamine pyrophosphate en [...] (562 aa)
ilvNCOGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR004789:IPR019455; KEGG: dhd:Dhaf_3616 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504585904; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (167 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
cysKCOGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR001926:IPR005859; KEGG: elm:ELI_3635 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; IMG reference gene:2504585945; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
AEB99463.1COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Chorismate mutase/prephenate dehydratase; IMG reference gene:2504585950; PFAM: Prephenate dehydratase; ACT domain. (296 aa)
aroFPhospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504585951; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (343 aa)
AEB99473.1Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR017821:IPR003702:IPR006472; KEGG: toc:Toce_1836 succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase; Citrate lyase, alpha subunit; PRIAM: Acetyl-CoA hydrolase; SPTR: Coenzyme A transferase PsecoA; TIGRFAM: Succinate CoA transferase; IMG reference gene:2504585960; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases. (499 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (473 aa)
AEB99509.1Acetolactate synthase; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR011766:IPR012001:IPR012000; KEGG: csh:Closa_0571 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central domain; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; IMG reference gene:2504585996; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine p [...] (604 aa)
AEB99511.1COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: glo:Glov_0789 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; IMG reference gene:2504585998; PFAM: 3-dehydroquinate synthase. (357 aa)
aepYPhosphonopyruvate decarboxylase; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR017684:IPR011766; KEGG: ols:Olsu_0592 phosphonopyruvate decarboxylase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Phosphonopyruvate decarboxylase; SPTR: Phosphonopyruvate decarboxylase; TIGRFAM: Phosphonopyruvate decarboxylase; IMG reference gene:2504586017; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase. (372 aa)
AEB99583.12-dehydropantoate 2-reductase; COGs: COG1893 Ketopantoate reductase; InterPro IPR003710:IPR013332:IPR013752; KEGG: swo:Swol_1181 putative oxidoreductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal; Ketopantoate reductase ApbA/PanE, C-terminal; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; IMG reference gene:2504586072; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase. (308 aa)
AEB99584.1COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: cdl:CDR20291_2923 glycerate kinase; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: Glycerate kinase; IMG reference gene:2504586073; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (382 aa)
AEB99686.1Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: ckr:CKR_1462 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methlytransferase, UbiE/COQ5 family; IMG reference gene:2504586181; PFAM: Methyltransferase domain. (229 aa)
AEB99692.1COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR000644:IPR001093; KEGG: cbe:Cbei_2114 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SPTR: Inosine-5'-monophosphate dehydrogenase; IMG reference gene:2504586187; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase. (500 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (375 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
AEB99717.1COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334:IPR004843; KEGG: afn:Acfer_0834 5'-nucleotidase domain protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: 5'-nucleotidase family protein; IMG reference gene:2504586215; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. (533 aa)
hemZCOGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cth:Cthe_1341 coproporphyrinogen III oxidase; PFAM: Radical SAM; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen oxidase, anaerobic; IMG reference gene:2504586229; PFAM: Radical SAM superfamily; TIGRFAM: coproporphyrinogen dehydrogenase HemZ. (508 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (229 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (161 aa)
aroHChorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (121 aa)
thrCCOGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: cth:Cthe_1381 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504586285; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (495 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (305 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (190 aa)
rfbBdTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: afn:Acfer_0578 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2504586291; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa)
deoDCOGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845:IPR004402; KEGG: lsa:LSA0797 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase deoD-type; TIGRFAM: Purine nucleoside phosphorylase; IMG reference gene:2504586300; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD). (237 aa)
AEB99793.1Trans-hexaprenyltranstransferase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: swo:Swol_0680 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Heptaprenyl diphosphate synthase component II; IMG reference gene:2504586302; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (324 aa)
AEB99797.1Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: chy:CHY_1808 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: Menaquinone biosynthesis decarboxylase, SCO4490 family; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504586306; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; menaquinone biosynthesis decarboxylase, SCO4490 family; Belongs t [...] (486 aa)
AEB99798.1COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: mta:Moth_0096 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Putative 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase-related; IMG reference gene:2504586307; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. (282 aa)
gltACOGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006004:IPR013027:IPR001327; KEGG: ckr:CKR_0405 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric; IMG reference gene:2504586314; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric. (468 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (265 aa)
hptCOGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: chy:CHY_1067 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504586335; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
AEB99910.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507:IPR003382; KEGG: cro:ROD_30701 putative 4-hydroxybenzoate decarboxylase subunit B; PFAM: Flavoprotein; SPTR: Phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Phenylacrylic acid decarboxylase; IMG reference gene:2504586424; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases. (190 aa)
AEB99954.1GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: sth:STH2891 acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504586472; PFAM: Acetyltransferase (GNAT) family; Belongs to the acetyltransferase family. (157 aa)
aroF-2Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504586473; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (337 aa)
AEB99956.1COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: gur:Gura_1463 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504586474; PFAM: Prephenate dehydrogenase. (293 aa)
AEB99960.1Alanine--glyoxylate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: hor:Hore_14780 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Alanine--glyoxylate transaminase; SPTR: 4-aminobutyrate transaminase; IMG reference gene:2504586478; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
purCCOGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636; KEGG: tle:Tlet_1916 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase; IMG reference gene:2504586494; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (237 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR010918:IPR000728; KEGG: afn:Acfer_1279 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504586495; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal dom [...] (350 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (203 aa)
purDCOGs: COG0151 Phosphoribosylamine-glycine ligase; InterPro IPR000115:IPR020561:IPR020562:IPR020560; KEGG: afn:Acfer_1276 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504586500; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) do [...] (425 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (294 aa)
argDCOGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: afn:Acfer_0596 acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; IMG reference gene:2504586511; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotra [...] (401 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (310 aa)
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR001518; KEGG: hmo:HM1_1436 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; IMG reference gene:2504586513; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
argHCOGs: COG0165 Argininosuccinate lyase; InterPro IPR022761:IPR009049; KEGG: vpr:Vpar_1567 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504586514; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (475 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa)
AEC00031.1Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: pth:PTH_1194 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Geranyltranstransferase; IMG reference gene:2504586551; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (295 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa)
rpeCOGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dau:Daud_1586 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504586596; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (214 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (394 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (222 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (449 aa)
hisBCOGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: cth:Cthe_2884 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; IMG reference gene:2504586612; PFAM: Imidazoleglycerol-phosphate dehydratase. (194 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa)
hisACOGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR006063; KEGG: dae:Dtox_0756 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; IMG referen [...] (243 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisEphosphoribosyl-ATP diphosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179:IPR002496:IPR021130; KEGG: ipo:Ilyop_2707 phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Histidine biosynthesis protein HisIE; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504586616; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFA [...] (235 aa)
pssACDP-diacylglycerol/serine O-phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR004533:IPR000462; KEGG: afn:Acfer_0770 CDP-diacylglycerol/serineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; IMG reference gene:2504586625; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (233 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (217 aa)
ribFRiboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. (321 aa)
ilvDCOGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: afn:Acfer_1425 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504586638; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (550 aa)
surEMultifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (250 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
AEC00144.1Aminotransferase class I and II; COGs: COG1448 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: afn:Acfer_0480 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; SPTR: Aspartate/aromatic aminotransferase; IMG reference gene:2504586664; PFAM: Aminotransferase class I and II. (414 aa)
AEC00145.1COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048:IPR002912:IPR005260; KEGG: vpr:Vpar_1126 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; IMG reference gene:2504586665; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (409 aa)
fbaFructose-1,6-bisphosphate aldolase, class II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: cce:Ccel_2222 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504586667; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, [...] (329 aa)
AEC00148.1Fructose-bisphosphate aldolase class-I; COGs: COG3588 Fructose-1 6-bisphosphate aldolase; InterPro IPR000741; KEGG: fjo:Fjoh_0953 fructose-1,6-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase, class-I; SPTR: Fructose-bisphosphate aldolase class-I; IMG reference gene:2504586668; PFAM: Fructose-bisphosphate aldolase class-I. (295 aa)
AEC00168.1COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR002035; KEGG: dsy:DSY3869 hypothetical protein; PFAM: von Willebrand factor, type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor, type A; SPTR: Magnesium-chelatase, subunit D/I family; IMG reference gene:2504586688; PFAM: von Willebrand factor type A domain; AAA domain (dynein-related subfamily). (648 aa)
AEC00169.1COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593; KEGG: aoe:Clos_2327 magnesium chelatase; PRIAM: Magnesium chelatase; SMART: ATPase, AAA+ type, core; SPTR: Magnesium chelatase, ATPase subunit I; IMG reference gene:2504586689; PFAM: Magnesium chelatase, subunit ChlI. (339 aa)
AEC00179.1HAD-superfamily hydrolase, subfamily IB (PSPase-like); COGs: COG0560 Phosphoserine phosphatase; InterPro IPR006383:IPR005834; KEGG: dds:Ddes_1017 HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like; IMG reference gene:2504586699; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; ATPase, P-type (transporting), HAD superfamily, subfamily IC. (199 aa)
AEC00181.1HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR006402:IPR005834; KEGG: dat:HRM2_44240 Gph2; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504586702; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4 [...] (224 aa)
ilvB-2Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR011766:IPR012001:IPR012000; KEGG: thx:Thet_0020 acetolactate synthase large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central domain; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase, large subunit; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504586707; PFAM: Thiamine py [...] (553 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
leuCHomoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
ilvN-2COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR004789:IPR019455; KEGG: ate:Athe_0503 acetolactate synthase small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504586712; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit. (176 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
AEC00198.1COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR002912; KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504586719; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (440 aa)
pheBCOGs: COG4492 ACT domain-containing protein; KEGG: afn:Acfer_1234 amino acid-binding ACT domain protein; SPTR: ACT domain-containing protein PheB; IMG reference gene:2504586720; Belongs to the UPF0735 family. (157 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (196 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (276 aa)
AEC00205.1COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: afn:Acfer_1240 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; IMG reference gene:2504586726; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (201 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (436 aa)
AEC00213.1COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: ere:EUBREC_1577 serine acetyltransferase, plasmid; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; IMG reference gene:2504586734; TIGRFAM: serine O-acetyltransferase. (317 aa)
LYS1COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: bha:BH3957 hypothetical protein; PFAM: Saccharopine dehydrogenase / Homospermidine synthase; SPTR: Saccharopine dehydrogenase; IMG reference gene:2504586739; PFAM: Saccharopine dehydrogenase. (399 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (319 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (415 aa)
AEC00258.1COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: afn:Acfer_0715 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504586779; PFAM: Aminotransferase class I and II. (394 aa)
AEC00260.1Putative transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: nth:Nther_1129 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Putative NirD protein; IMG reference gene:2504586781. (150 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (556 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (355 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
cdsAPhosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: afn:Acfer_1376 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; IMG reference gene:2504586920; PFAM: Cytidylyltransferase family; Belongs to the CDS family. (276 aa)
uppSUndecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (258 aa)
ilvECOGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544:IPR005786; KEGG: eel:EUBELI_01912 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid transaminase; TIGRFAM: Branched-chain amino acid aminotransferase II; IMG reference gene:2504586939; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. (341 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (404 aa)
ribECOGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. (217 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa)
AEC00473.1Sugar-phosphate isomerase, RpiB/LacA/LacB family; COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: sth:STH77 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: Ribose/galactose isomerase; IMG reference gene:2504587001; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family. (151 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCSuccinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
AEC00497.1Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cpy:Cphy_3574 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative radical SAM domain protein; IMG reference gene:2504587025; PFAM: Radical SAM superfamily. (590 aa)
AEC00525.1COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR001327; KEGG: cpy:Cphy_3412 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, homotetrameric; IMG reference gene:2504587054; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (409 aa)
AEC00548.1COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR010918:IPR010141; KEGG: tjr:TherJR_0822 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase-related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; IMG reference gene:2504587077; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II. (1261 aa)
nifJCOGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR019456:IPR011895:IPR002880:IPR011766:IPR 019752; KEGG: cbi:CLJ_B2987 pyruvate ferredoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyruvate-flavodoxin oxidoreductase; [...] (1174 aa)
AEC00572.1LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily. (409 aa)
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
sdhBCOGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: bsu:BSU28430 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase, iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; IMG reference gene:2504587114; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (250 aa)
sdhACOGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR004112:IPR011280:IPR003953; KEGG: lsp:Bsph_4053 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase, flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504587115; PFAM: domain; FAD binding domain; TIGRFAM [...] (600 aa)
sdhCInterPro IPR011138:IPR000701; KEGG: afl:Aflv_0580 succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit; SPTR: Succinate dehydrogenase cytochrome B558 subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b558 subunit; IMG reference gene:2504587116; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (210 aa)
AEC00585.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: vpr:Vpar_1528 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; IMG reference gene:2504587117; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate s [...] (185 aa)
AEC00586.1Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: vpr:Vpar_1529 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; IMG reference gene:2504587118; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tart [...] (280 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
ispE4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (287 aa)
AEC00612.1Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (322 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (81 aa)
fabG3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
fabDCOGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410:IPR020801; KEGG: vpr:Vpar_0698 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2504587218; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (314 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (356 aa)
AEC00703.1Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: nla:NLA_12940 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; IMG reference gene:2504587237; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (189 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (499 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpB-2Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (430 aa)
trpCCOGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: gme:Gmet_2494 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; IMG reference gene:2504587241; PFAM: Indole-3-glycerol phosphate synthase. (266 aa)
trpFCOGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: gem:GM21_2257 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; IMG reference gene:2504587242; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (206 aa)
AEC00719.1Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (385 aa)
AEC00722.1PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013; KEGG: str:Sterm_1709 histidinol phosphate phosphatase HisJ family; PFAM: PHP, C-terminal; SPTR: Histidinol-phosphatase; IMG reference gene:2504587256; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily. (282 aa)
AEC00724.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3350 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504587258; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain. (330 aa)
AEC00725.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3352 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Nitrite reductase heme biosynthesis J protein; IMG reference gene:2504587259; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain. (398 aa)
AEC00732.1COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: mpd:MCP_0979 putative threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; IMG reference gene:2504587267; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (331 aa)
AEC00733.1Biotin carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005482:IPR005479:IPR005481; KEGG: tjr:TherJR_1719 acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Biotin carboxylase, C-terminal; Carbamoyl-phosphate synthase, large subunit, N-terminal; PRIAM: Biotin carboxylase; SMART: Biotin carboxylase, C-terminal; SPTR: Acetyl-CoA carboxylase, biotin carboxylase subunit; IMG reference gene:2504587268; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal [...] (468 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (365 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (384 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
AEC00839.1Oligo-1,6-glucosidase; COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: bmd:BMD_3759 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Oligo-1,6-glucosidase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Alpha-glucosidase; IMG reference gene:2504587379; PFAM: Alpha amylase, catalytic domain. (554 aa)
AEC00841.1Hexokinase; COGs: COG5026 Hexokinase; InterPro IPR022673:IPR022672; KEGG: hmo:HM1_0763 hexokinase, putative; PFAM: Hexokinase, N-terminal; Hexokinase, C-terminal; PRIAM: Hexokinase; SPTR: Glucokinase; IMG reference gene:2504587381; PFAM: Hexokinase. (428 aa)
glpAGlycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR007419:IPR017752:IPR006076; KEGG: drm:Dred_2844 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD-like [2Fe-2S]-binding domain; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, A subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic A subunit; IMG reference gene:2504587412; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydroge [...] (535 aa)
glpBGlycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR009158:IPR003953; KEGG: dds:Ddes_1520 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, B subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic B subunit; IMG reference gene:2504587413; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerob [...] (408 aa)
glpCGlycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017753; KEGG: dds:Ddes_1519 sn-glycerol-3-phosphate dehydrogenase subunit C; PFAM: Cysteine-rich domain; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, C subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic C subunit; IMG reference gene:2504587414; PFAM: Cysteine-rich domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. (408 aa)
glyA-2COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase. (444 aa)
AEC00882.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: cpy:Cphy_1317 FAD linked oxidase domain-containing protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; IMG reference gene:2504587424; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (465 aa)
pgiPhosphoglucose isomerase (PGI); COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: vpr:Vpar_0658 phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504587451; PFAM: Phosphoglucose isomerase. (485 aa)
galUUTP-glucose-1-phosphate uridylyltransferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: cpf:CPF_0483 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; IMG reference gene:2504587452; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase. (302 aa)
AEC00910.1Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005846:IPR005845:IPR005844:IPR005843; KEGG: dae:Dtox_0895 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; SPTR: Phosphomannomutase; IMG reference gene:2504587453; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain [...] (450 aa)
AEC00943.1L-asparaginase, type II; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034:IPR004550; KEGG: bpr:GBP346_A2376 L-asparaginase (L-asparagine amidohydrolase) (L-ASNase); PFAM: Asparaginase/glutaminase; PRIAM: Asparaginase; SMART: Asparaginase/glutaminase; SPTR: L-asparaginase; TIGRFAM: L-asparaginase, type II; IMG reference gene:2504587508; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type II; Belongs to the asparaginase 1 family. (328 aa)
AEC00963.1Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (489 aa)
serACOGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: pth:PTH_0012 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504587536; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hy [...] (527 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (478 aa)
glgB1,4-alpha-glucan-branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (757 aa)
glgPGlycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (813 aa)
glgDGlucose-1-phosphate adenylyltransferase, GlgD subunit; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011832:IPR005835; KEGG: drm:Dred_1456 glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase, GlgD subunit; TIGRFAM: Glucose-1-phosphate adenylyltransferase, GlgD subunit; IMG reference gene:2504587544; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit. (368 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (384 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa)
AEC01002.1Beta-fructofuranosidase; COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148:IPR001362; KEGG: cbt:CLH_3235 sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolases family 32, N-terminal; PRIAM: Beta-fructofuranosidase; SMART: Glycoside hydrolase, family 32; SPTR: Sucrose-6-phosphate dehydrogenase; IMG reference gene:2504587570; PFAM: Glycosyl hydrolases family 32 N-terminal domain. (493 aa)
AEC01005.1COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR004013; KEGG: cac:CA_C2727 histidinol-phosphatase; PFAM: PHP, C-terminal; PRIAM: Histidinol-phosphatase; SPTR: Putative histidinol-phosphatase; TIGRFAM: Histidinol phosphate phosphatase, HisJ; IMG reference gene:2504587573; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; Belongs to the PHP hydrolase family. HisK subfamily. (258 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: cth:Cthe_0138 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504587608; PFAM: Phosphoglycerate kinase. (405 aa)
gapCOGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bpb:bpr_I2050 glyceraldehyde-3-phosphate dehydrogenase Gap; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG refer [...] (337 aa)
AEC01058.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (370 aa)
AEC01131.1Aconitate hydratase; COGs: COG1048 Aconitase A; InterPro IPR006250:IPR001030:IPR000573; KEGG: tjr:TherJR_2355 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Putative aconitate hydratase; TIGRFAM: Aconitase, putative; IMG reference gene:2504587702; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type. (644 aa)
AEC01132.1COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: csh:Closa_2133 citrate synthase; PFAM: Citrate synthase-like; SPTR: 2-methylcitrate synthase; IMG reference gene:2504587703; PFAM: Citrate synthase; Belongs to the citrate synthase family. (446 aa)
AEC01133.1COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804; KEGG: amt:Amet_1319 isocitrate dehydrogenase (NAD(+)); PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NAD(+)); SPTR: Isocitrate dehydrogenase; IMG reference gene:2504587704; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NAD-dependent, mitochondrial type; isopropylmalate/isohomocitrate dehydrogenases. (333 aa)
pykCOGs: COG0469 Pyruvate kinase; InterPro IPR015795:IPR001697:IPR015793; KEGG: vpr:Vpar_1405 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504587705; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
patBCystathionine beta-lyase; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: elm:ELI_3637 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Cystathionine beta-lyase; SPTR: Hemolysin; IMG reference gene:2504587722; PFAM: Aminotransferase class I and II. (390 aa)
AEC01153.1Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: amt:Amet_3707 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Cystathionine beta-lyase; IMG reference gene:2504587724; PFAM: Cys/Met metabolism PLP-dependent enzyme. (379 aa)
mqnCFO synthase, subunit 2; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (346 aa)
mqnE-2FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (366 aa)
AEC01189.1COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dhd:Dhaf_4517 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504587761; PFAM: Cysteine-rich domain. (444 aa)
AEC01190.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: mta:Moth_2308 FAD linked oxidase-like; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; IMG reference gene:2504587762; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (461 aa)
purBCOGs: COG0015 Adenylosuccinate lyase; InterPro IPR022761:IPR004769:IPR019468; KEGG: bhy:BHWA1_00426 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504587766; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (430 aa)
AEC01214.1COGs: COG0620 Methionine synthase II (cobalamin-independent); InterPro IPR002629; KEGG: afn:Acfer_0167 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase, vitamin-B12 independent; SPTR: Vitamin-B12 independent methionine synthase family protein; IMG reference gene:2504587787; PFAM: Cobalamin-independent synthase, Catalytic domain. (372 aa)
ilvACOGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR005789; KEGG: clj:CLJU_c15090 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; IMG reference gene:2504587795; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form. (415 aa)
AEC01231.1COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR006158:IPR003759:IPR003726:IPR000489; KEGG: hmo:HM1_2499 methionine synthase, putative; PFAM: Homocysteine S-methyltransferase; Cobalamin (vitamin B12)-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Pterin-binding; PRIAM: Methionine synthase; SPTR: Vitamin B12-dependent methionine synthase family protein; IMG reference gene:2504587804; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahyd [...] (790 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
AEC01233.1Phosphoribosylaminoimidazolecarboxamide formyltransferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme. (390 aa)
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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