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| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (432 aa) |
| | Mmah_1729 | Protein of unknown function UPF0044; COGs: COG1534 RNA-binding protein containing KH domain possibly ribosomal protein; InterPro IPR001890; KEGG: ftn:FTN_0552 RNA-binding protein; PFAM: protein of unknown function UPF0044; SPTR: Q12W46 Putative uncharacterized protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: conserved hypothetical protein TIGR00253. (85 aa) |
| | nop10 | RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (51 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (408 aa) |
| | pelA | Cell division protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (349 aa) |
| | Mmah_1686 | COGs: COG2036 Histones H3 and H4; InterPro IPR007125:IPR003958; PFAM: Transcription factor CBF/NF-Y/histone domain protein; Histone core domain protein; SPTR: Q12W85 Archaeal histone; PFAM: Histone-like transcription factor (CBF/NF-Y) and archaeal histone. (73 aa) |
| | leuS | COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015413:IPR002300:IPR013155:IPR001412:IPR 004493; KEGG: leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); SPTR: Q12WA2 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, archaeal and cytosolic family. (961 aa) |
| | Mmah_1659 | Protein of unknown function DUF509; COGs: COG1617 conserved hypothetical protein; InterPro IPR007510; PFAM: Protein of unknown function DUF509; SPTR: Q12WA3 Putative uncharacterized protein; PFAM: Kinase binding protein CGI-121. (169 aa) |
| | Mmah_1657 | MiaB-like tRNA modifying enzyme; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR007197:IPR002792:IPR013848:IPR006638:IPR 005839:IPR006466; KEGG: cdkal1; CDK5 regulatory subunit associated protein 1-like 1; PFAM: Radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q12WA5 MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-l [...] (406 aa) |
| | thrS | Ser-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158:IPR002314:IPR004154:IPR015011:IPR 006195:IPR002320; KEGG: dma:DMR_10590 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; Anticodon-binding domain protein; tRNA synthetase class II (G H P and S); SPTR: Q12WD4 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); Archaea-specific editing domain of threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II [...] (631 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (391 aa) |
| | truD | tRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (438 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa) |
| | rpoK | DNA-directed RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | rpoN | DNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa) |
| | rps9 | COGs: COG0103 Ribosomal protein S9; InterPro IPR000754:IPR020574:IPR019958; KEGG: Hypothetical protein CBG11589; K02960 small subunit ribosomal protein S16e; PFAM: ribosomal protein S9; SPTR: Q12TI5 30S ribosomal protein S9P; TIGRFAM: ribosomal protein S9P; PFAM: Ribosomal protein S9/S16; TIGRFAM: archaeal ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | hisS | COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR002314:IPR004154:IPR006195:IPR015807; KEGG: sat:SYN_02534 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Q12TM4 Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; ATP phosphoribosyltransferase, regulatory subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (502 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (570 aa) |
| | Mmah_1450 | ATP synthase H subunit; InterPro IPR014275; KEGG: actin; SPTR: Q12WL7 H(+)-transporting ATP synthase, subunit H; TIGRFAM: ATP synthase H subunit; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase archaeal, H subunit. (108 aa) |
| | Mmah_1424 | Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: geo:Geob_0482 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q8PVQ8 Putative uncharacterized protein; PFAM: Rhodanese-like domain. (89 aa) |
| | Mmah_1417 | PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: dal:Dalk_3059 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Q12TG3 PHP-like protein; PFAM: PHP domain. (221 aa) |
| | endA | tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (346 aa) |
| | Mmah_1383 | PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR018317:IPR020554:IPR000541; KEGG: Hypothetical protein CBG01646; PFAM: PP-loop domain protein; Queuosine synthesis-like; SPTR: Q12X95 Putative uncharacterized protein; PFAM: PP-loop family; TIGRFAM: conserved hypothetical protein TIGR00269. (305 aa) |
| | Mmah_1376 | Radical SAM superfamily protein; COGs: COG0731 Fe-S oxidoreductase; InterPro IPR005829; KEGG: sat:SYN_01173 radical SAM superfamily protein; SPTR: Q12WV2 Fe-S protein, radical SAM family; PFAM: Radical SAM superfamily. (328 aa) |
| | rnp1 | Ribonuclease P protein subunit Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (102 aa) |
| | truB | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (342 aa) |
| | rnhB | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (215 aa) |
| | pheT | COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR005146:IPR005147:IPR004531; KEGG: phenylalanyl-tRNA synthetase beta chain (EC:6.1.1.20); K01890 phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetase B5; B3/4 domain protein; PRIAM: Phenylalanine--tRNA ligase; SPTR: Q12YP2 Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (539 aa) |
| | Mmah_1277 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (175 aa) |
| | rpoD | DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa) |
| | Mmah_1234 | Protein of unknown function UPF0066; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: sfu:Sfum_0270 hypothetical protein; PFAM: protein of unknown function UPF0066; SPTR: Q46EB9 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: conserved hypothetical protein TIGR00104. (130 aa) |
| | Mmah_1226 | Radical SAM domain protein; COGs: COG1244 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR005909; KEGG: glo:Glov_3168 conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q12ZP7 Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR01210. (346 aa) |
| | Mmah_1192 | Protein of unknown function DUF367; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (168 aa) |
| | Mmah_1184 | PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: dol:Dole_1503 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: A0YTK4 Putative uncharacterized protein; PFAM: PHP domain. (286 aa) |
| | Mmah_1183 | Metal dependent phosphohydrolase; COGs: COG1418 HD superfamily hydrolase; InterPro IPR006674:IPR003607:IPR006675; KEGG: dma:DMR_37240 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q12YV8 Uncharacterized domain HDIG; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00295; uncharacterized domain HDIG. (170 aa) |
| | tfe | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (164 aa) |
| | Mmah_1163 | Protein of unknown function DUF88; COGs: COG1432 conserved hypothetical protein; InterPro IPR002790; KEGG: spc:Sputcn32_0704 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q12XM0 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88; TIGRFAM: conserved hypothetical protein TIGR00288. (169 aa) |
| | trm1 | N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (386 aa) |
| | taw2 | Methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (340 aa) |
| | Mmah_1111 | Protein of unknown function DUF88; COGs: COG1432 conserved hypothetical protein; InterPro IPR002790; KEGG: sat:SYN_03101 putative cytoplasmic protein; PFAM: protein of unknown function DUF88; PFAM: Protein of unknown function DUF88; TIGRFAM: conserved hypothetical protein TIGR00288. (206 aa) |
| | rtcA | RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (351 aa) |
| | cysS | COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015413:IPR015273:IPR002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); PRIAM: Cysteine--tRNA ligase; SPTR: Q9UWP1 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase. (471 aa) |
| | Mmah_1073 | Beta-lactamase domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001279:IPR001763; KEGG: sat:SYN_01287 hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q8TNG7 Metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (456 aa) |
| | Mmah_1037 | Beta-lactamase domain protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR001279; KEGG: dal:Dalk_3435 beta-lactamase domain protein; PFAM: beta-lactamase domain protein; SPTR: Q12Y29 Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily. (253 aa) |
| | trmY | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (200 aa) |
| | pus10 | THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (430 aa) |
| | Mmah_1030 | DNA-directed RNA polymerase, subunit F; COGs: COG1460 conserved hypothetical protein; InterPro IPR005574; KEGG: bpt:Bpet3134 transcription elongation factor NusA; PFAM: RNA polymerase Rpb4; SPTR: Q12XH5 DNA-directed RNA polymerase, subunit F; PFAM: RNA polymerase Rpb4. (117 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (229 aa) |
| | Mmah_0987 | COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: pca:Pcar_2118 hypothetical protein; PFAM: amino acid-binding ACT domain protein; SPTR: Q466X6 Phosphoserine phosphatase; PFAM: ACT domain; Belongs to the UPF0237 family. (92 aa) |
| | Mmah_0940 | Protein of unknown function DUF88; COGs: COG1432 conserved hypothetical protein; InterPro IPR002790; KEGG: pin:Ping_3258 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: C1VK79 Uncharacterized conserved protein; PFAM: Protein of unknown function DUF88. (161 aa) |
| | Mmah_0939 | PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063; KEGG: hypothetical protein; PFAM: PP-loop domain protein; SPTR: A7IA74 PP-loop domain protein; PFAM: PP-loop family. (255 aa) |
| | Mmah_0898 | SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: mfa:Mfla_0093 SirA-like protein; PFAM: SirA family protein; SPTR: Q12ZL8 SirA-like protein; PFAM: SirA-like protein. (73 aa) |
| | rpl7ae | LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (117 aa) |
| | rps28e | COGs: COG2053 Ribosomal protein S28E/S33; InterPro IPR000289; KEGG: RpS28a; Ribosomal protein S28a; K02979 small subunit ribosomal protein S28e; PFAM: Ribosomal protein S28e; SPTR: Q12Z96 SSU ribosomal protein S28E; PFAM: Ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (443 aa) |
| | Mmah_0801 | InterPro IPR018675; PFAM: Protein of unknown function DUF2144; SPTR: Q12ZB2 Putative uncharacterized protein; PFAM: Transcription factor Pcc1. (80 aa) |
| | Mmah_0800 | Exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component contains IMP4 domain; Probably involved in the biogenesis of the ribosome. (150 aa) |
| | rpoP | DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (45 aa) |
| | rrp42 | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (261 aa) |
| | rrp41 | Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (297 aa) |
| | rrp4 | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (255 aa) |
| | rnp2 | Ribonuclease P-related protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (122 aa) |
| | rnp3 | Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (237 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (478 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1056 aa) |
| | Mmah_0775 | Small nuclear ribonucleoprotein, LSM family; InterPro IPR001163:IPR006649; KEGG: SAD1; SAD1 (SUPERSENSITIVE TO ABA AND DROUGHT 1); PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein; SPTR: Q8PUF1 Small nuclear riboprotein-like protein; PFAM: LSM domain. (75 aa) |
| | Mmah_0735 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (355 aa) |
| | Mmah_0719 | tRNA(Ile2) 2-agmatinylcytidine synthetase; COGs: COG1571 DNA-binding protein containing a Zn-ribbon domain; InterPro IPR013696:IPR017674; PFAM: domain of unknown function DUF1743; SPTR: Q12YG2 Putative uncharacterized protein; TIGRFAM: methanogenesis marker protein 11; PFAM: Domain of unknown function (DUF1743); TIGRFAM: putative methanogenesis marker protein 11. (303 aa) |
| | Mmah_0710 | SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: tbd:Tbd_1982 hypothetical protein; PFAM: SirA family protein; SPTR: B8GJE1 SirA family protein; PFAM: SirA-like protein. (78 aa) |
| | Mmah_0699 | Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (397 aa) |
| | Mmah_0697 | SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: wsu:WS1004 hypothetical protein; PFAM: SirA family protein; SPTR: O29697 UPF0033 protein AF_0554; PFAM: SirA-like protein. (81 aa) |
| | glyS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (585 aa) |
| | Mmah_0688 | Sjogrens syndrome scleroderma autoantigen 1; COGs: COG1645 Uncharacterized Zn-finger containing protein; InterPro IPR009563; KEGG: hypothetical protein; PFAM: Sjogrens syndrome scleroderma autoantigen 1; SPTR: Q8PX36 Putative uncharacterized protein; PFAM: Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27). (163 aa) |
| | Mmah_0686 | Translin; COGs: COG2178 RNA-binding protein of the translin family; InterPro IPR002848; KEGG: TRA1; translin-like protein; PFAM: Translin; SPTR: Q8TUH6 Translin family protein; PFAM: Translin family. (211 aa) |
| | sepS | phosphoserine-tRNA(Cys) ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa) |
| | tgtA | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (491 aa) |
| | Mmah_0669 | KH domain protein; COGs: COG1094 RNA-binding protein (contains KH domains); InterPro IPR018111:IPR004087:IPR004088:IPR019964; KEGG: similarity to HYPOTHETICAL PROTEIN Y443_METJA; K11884 RNA-binding protein PNO1; PFAM: K Homology, type 1, subgroup; SMART: KH domain protein; SPTR: Q12XD6 KH type RNA-binding protein; TIGRFAM: KH domain protein; PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein. (178 aa) |
| | Mmah_0654 | COGs: COG2520 methyltransferase; InterPro IPR013216:IPR003402; KEGG: TRM5; tRNA-(N1G37) methyltransferase; K07055; PFAM: protein of unknown function Met10; Methyltransferase type 11; SPTR: Q46CP0 Methyltransferase; PFAM: Met-10+ like-protein; TIGRFAM: methyltransferase, FkbM family. (331 aa) |
| | tfb | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa) |
| | Mmah_0651 | Hypothetical protein; SPTR: Q8PW30 Putative uncharacterized protein; PFAM: Gar1/Naf1 RNA binding region. (86 aa) |
| | Mmah_0629 | RNA methyltransferase, TrmH family, group 1; COGs: COG0565 rRNA methylase; InterPro IPR001537:IPR004384; KEGG: gsu:GSU1475 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: Q8PVX0 RNA methylase; TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. (231 aa) |
| | cca | tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (445 aa) |
| | nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (141 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (385 aa) |
| | Mmah_0531 | DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (886 aa) |
| | Mmah_0530 | DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa) |
| | Mmah_0529 | COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterPro IPR007642:IPR007645:IPR007644; KEGG: NRPB2; NRPB2 (EMBRYO DEFECTIVE 1989); DNA binding; K03010 DNA-directed RNA polymerase II subunit B; PFAM: RNA polymerase beta subunit; RNA polymerase Rpb2 domain 3; RNA polymerase Rpb2 domain 2; SPTR: Q12WS4 DNA-directed RNA polymerase, subunit B'; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; Belongs to the RNA polymerase beta chain family. (545 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa) |
| | Mmah_0520 | Metal dependent phosphohydrolase; COGs: COG1418 HD superfamily hydrolase; InterPro IPR006674:IPR003607:IPR006675; KEGG: dal:Dalk_2318 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q12WS0 Metal-dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (215 aa) |
| | Mmah_0511 | PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: dal:Dalk_2412 response regulator receiver protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Q12WR1 PHP-like protein; PFAM: PHP domain. (211 aa) |
| | Mmah_0508 | COGs: COG3642 Mn2+-dependent serine/threonine protein kinase; InterPro IPR018934:IPR000719; KEGG: similar to TP53-regulating kinase (p53-related protein kinase) (Nori-2); K08851 TP53 regulating kinase; PFAM: RIO-like kinase; SPTR: Q12WQ8 O-sialoglycoprotein endopeptidase; PFAM: RIO1 family. (189 aa) |
| | kae1 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (330 aa) |
| | Mmah_0490 | COGs: COG1095 DNA-directed RNA polymerase subunit E'; InterPro IPR003029:IPR005576:IPR004519; KEGG: hypothetical protein; K03015 DNA-directed RNA polymerase II subunit G; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein; PRIAM: DNA-directed RNA polymerase; SPTR: Q12TT6 DNA-directed RNA polymerase, subunit E'; TIGRFAM: DNA-directed RNA polymerase; PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form. (187 aa) |
| | Mmah_0489 | COGs: COG1412 Uncharacterized protein of PilT N-term./Vapc superfamily; SPTR: Q12TT7 Putative uncharacterized protein; PFAM: Fcf1. (121 aa) |
| | Mmah_0468 | 4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR001450:IPR017900; KEGG: dal:Dalk_4692 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q12X35 4Fe-4S ferredoxin, iron-sulfur binding; TIGRFAM: iron-sulfur cluster binding protein, putative. (231 aa) |
| | Mmah_0439 | PUA domain containing protein; COGs: COG1370 Prefoldin molecular chaperone implicated in de novo protein folding alpha subunit; InterPro IPR002478; PFAM: PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Q12U05 PUA domain protein; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. (159 aa) |
| | rtcB | Protein of unknown function UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: dol:Dole_2571 hypothetical protein; PFAM: protein of unknown function UPF0027; SPTR: Q12U04 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0027; Belongs to the RtcB family. (493 aa) |
| | Mmah_0437 | Archease family protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (142 aa) |
| | Mmah_0389 | COGs: COG1594 DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS; InterPro IPR001529:IPR001222:IPR019761:IPR006288; KEGG: hypothetical protein; K03019 DNA-directed RNA polymerase III subunit C11; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SPTR: Q12U17 DNA-directed RNA polymerase, subunit M; TIGRFAM: transcription factor S; PFAM: RNA polymerases M/15 Kd subunit; Transcription factor S-II (TFIIS); TIGRFAM: transcription factor S, archaeal. (104 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (351 aa) |
| | Mmah_0384 | Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (459 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (924 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (865 aa) |
| | Mmah_0362 | Small nuclear ribonucleoprotein, LSM family; COGs: COG1958 Small nuclear ribonucleoprotein (snRNP) homolog; InterPro IPR001163:IPR006649; KEGG: hypothetical protein; K04796 small nuclear ribonucleoprotein; PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein; SPTR: Q12U30 Putative snRNP Sm-like protein; PFAM: LSM domain; Belongs to the snRNP Sm proteins family. (72 aa) |
| | Mmah_0350 | TIM-barrel protein, nifR3 family; COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR018517:IPR004652; KEGG: hsm:HSM_1609 nifR3 family TIM-barrel protein; PFAM: dihydrouridine synthase DuS; SPTR: Q12U52 Dihydrouridine synthase, DuS; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family. (317 aa) |
| | Mmah_0309 | tRNA methyltransferase complex GCD14 subunit; COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816:IPR016130; KEGG: dde:Dde_0539 protein-L-isoaspartate methyltransferase-like; PFAM: tRNA methyltransferase complex GCD14 subunit; SPTR: Q12U81 Putative methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit. (250 aa) |
| | rnz | RNAse Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (312 aa) |
| | Mmah_0289 | Protein of unknown function DUF88; InterPro IPR002790; KEGG: reh:H16_A3546 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q12YH4 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. (258 aa) |
| | Mmah_0286 | COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; SPTR: Q12UA6 Putative uncharacterized protein. (227 aa) |
| | pylS | Pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (404 aa) |
| | Mmah_0230 | Histone acetyltransferase, ELP3 family; COGs: COG1243 Histone acetyltransferase; InterPro IPR000182:IPR007197:IPR006638:IPR005910; KEGG: elpc-3; ELongator complex Protein Component; K07739 elongator complex protein 3; PFAM: GCN5-related N-acetyltransferase; Radical SAM domain protein; PRIAM: Histone acetyltransferase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q12UK8 Histone acetyltransferase, ELP3 family; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family; radical SAM protein [...] (543 aa) |
| | Mmah_0177 | Protein of unknown function DUF516; COGs: COG1650 conserved hypothetical protein; InterPro IPR007508; KEGG: hypothetical protein; PFAM: Protein of unknown function DUF516; SPTR: Q12UQ4 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-aminoacyl-tRNA deacylase; Belongs to the DtdA deacylase family. (449 aa) |
| | Mmah_0176 | Protein of unknown function Met10; COGs: COG2520 methyltransferase; InterPro IPR003402; KEGG: dps:DP0629 hypothetical protein; PFAM: protein of unknown function Met10; SPTR: Q0W4W1 Putative uncharacterized protein; PFAM: Met-10+ like-protein. (273 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa) |
| | Mmah_0144 | InterPro IPR015011; KEGG: sfu:Sfum_0182 hypothetical protein; PFAM: Threonyl-tRNA synthetase editing domain protein; SPTR: A7I9Y6 Putative uncharacterized protein; PFAM: Archaea-specific editing domain of threonyl-tRNA synthetase. (136 aa) |
| | Mmah_0139 | Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: gem:GM21_3931 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q12VR2 Rhodanese-like protein; PFAM: Rhodanese-like domain. (139 aa) |
| | flpA | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa) |
| | Mmah_0049 | 4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR001450:IPR017900; KEGG: dal:Dalk_1124 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8TIA6 Putative uncharacterized protein. (230 aa) |
| | Mmah_0030 | N2-methylguanosine tRNA methyltransferase; COGs: COG1041 DNA modification methylase; InterPro IPR013216:IPR000241:IPR004114:IPR002052; KEGG: bja:bll7234 hypothetical protein; PFAM: putative RNA methylase; Methyltransferase type 11; SPTR: Q12VJ9 Putative RNA methylase; PFAM: Putative RNA methylase family UPF0020; THUMP domain; TIGRFAM: conserved hypothetical protein TIGR01177. (345 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (273 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (439 aa) |
| | kptA | Phosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (207 aa) |
| | argS | COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR015945:IPR005148:IPR008909:IPR001412:IPR 001278; KEGG: dvl:Dvul_1814 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Q12V97 Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (567 aa) |
| | taw1 | Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (310 aa) |
| | Mmah_2001 | Protein of unknown function DUF86; COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: gur:Gura_4166 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: B5IVQ5 Putative uncharacterized protein; PFAM: Protein of unknown function DUF86. (112 aa) |
| | Mmah_1978 | Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (237 aa) |
| | Mmah_1951 | tRNA-archaeosine synthase; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR002616:IPR004521; PFAM: PUA domain containing protein; Queuine/other tRNA-ribosyltransferase; SMART: PUA domain containing protein; SPTR: Q12V65 tRNA-guanine transglycosylases, various specificities; TIGRFAM: tRNA-guanine transglycosylase, various specificities; PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; uncharacterized domain 2. (610 aa) |
| | Mmah_1921 | COGs: COG1439 nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module; InterPro IPR006596; KEGG: GF10341 gene product from transcript GF10341-RA; K11883 RNA-binding protein NOB1; SMART: Nucleotide binding protein PINc; SPTR: Q12V33 Putative uncharacterized protein. (158 aa) |
| | tiaS | tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (425 aa) |
| | lysS | COGs: COG1384 Lysyl-tRNA synthetase (class I); InterPro IPR002904:IPR001412; KEGG: noc:Noc_1618 lysine--tRNA ligase; PFAM: Lysyl-tRNA synthetase class 1c; PRIAM: Lysine--tRNA ligase; SPTR: Q12UX8 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa) |
| | fen | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (339 aa) |
| | tbp | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa) |
| | rnp4 | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (103 aa) |
| | Mmah_1763 | tRNA(His)-5'-guanylyltransferase; COGs: COG4021 conserved hypothetical protein; InterPro IPR007537; KEGG: scl:sce6062 hypothetical protein; PFAM: protein of unknown function DUF549; SPTR: Q12W05 Putative uncharacterized protein; PFAM: tRNAHis guanylyltransferase. (243 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa) |
| | Mmah_1745 | Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa) |
| | rpoL | DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (91 aa) |
| | csl4 | RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (258 aa) |
| | pheS | COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR002319:IPR006195:IPR004529; KEGG: similar to predicted protein; K01889 phenylalanyl-tRNA synthetase alpha chain; PFAM: phenylalanyl-tRNA synthetase class IIc; PRIAM: Phenylalanine--tRNA ligase; SPTR: Q12W38 Phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit. (491 aa) |
