STRINGSTRING
Mmah_1621 Mmah_1621 pfkC pfkC pgk pgk Mmah_1806 Mmah_1806 gpmI gpmI prs prs Mmah_1948 Mmah_1948 Mmah_1954 Mmah_1954 Mmah_1959 Mmah_1959 tmk tmk eno eno ribK ribK Mmah_0985 Mmah_0985 Mmah_0174 Mmah_0174 Mmah_0135 Mmah_0135 pyrH pyrH Mmah_0111 Mmah_0111 Mmah_0019 Mmah_0019 Mmah_1558 Mmah_1558 Mmah_0997 Mmah_0997 Mmah_1016 Mmah_1016 aroK aroK Mmah_1063 Mmah_1063 Mmah_1079 Mmah_1079 Mmah_1151 Mmah_1151 gap gap nadK nadK Mmah_1199 Mmah_1199 argB argB Mmah_1249 Mmah_1249 Mmah_1250 Mmah_1250 Mmah_1327 Mmah_1327 cmk cmk adk adk Mmah_1393 Mmah_1393 Mmah_1394 Mmah_1394 Mmah_1400 Mmah_1400 Mmah_1503 Mmah_1503 Mmah_1509 Mmah_1509 mvk mvk Mmah_1550 Mmah_1550 Mmah_1554 Mmah_1554 Mmah_0974 Mmah_0974 Mmah_0969 Mmah_0969 thiM thiM Mmah_0922 Mmah_0922 Mmah_0912 Mmah_0912 Mmah_0911 Mmah_0911 Mmah_0908 Mmah_0908 Mmah_0873 Mmah_0873 Mmah_0868 Mmah_0868 ndk ndk Mmah_0832 Mmah_0832 Mmah_0831 Mmah_0831 Mmah_0821 Mmah_0821 mptE mptE Mmah_0778 Mmah_0778 Mmah_1620 Mmah_1620 ppk ppk Mmah_0747 Mmah_0747 Mmah_0670 Mmah_0670 Mmah_0650 Mmah_0650 Mmah_0649 Mmah_0649 proB proB Mmah_0609 Mmah_0609 Mmah_0526 Mmah_0526 Mmah_0516 Mmah_0516 Mmah_0508 Mmah_0508 Mmah_0496 Mmah_0496 Mmah_0492 Mmah_0492 Mmah_0428 Mmah_0428 Mmah_0349 Mmah_0349 Mmah_0343 Mmah_0343 thiL thiL tpiA tpiA apgM apgM Mmah_0221 Mmah_0221 Mmah_0205 Mmah_0205
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mmah_1621COGs: COG2054 Uncharacterized kinase related to aspartokinase uridylate kinase; InterPro IPR001048; KEGG: mei:Msip34_1490 aspartate/glutamate/uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Q8TQR7 Amino acid kinase; PFAM: Amino acid kinase family. (209 aa)
pfkCADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (491 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: ppd:Ppro_1694 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Q12WB3 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (413 aa)
Mmah_1806COGs: COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzyme; InterPro IPR010551; KEGG: stm:STM2757 putative cytoplasmic protein; PFAM: glucose-6-phosphate isomerase; SPTR: Q12VW6 Glucose-6-phosphate isomerase; PFAM: Glucose-6-phosphate isomerase (GPI). (243 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (514 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (282 aa)
Mmah_1948Multi-sensor signal transduction histidine kinase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR001789:IPR013767:IPR013656:IPR003661:IPR 000014:IPR000700:IPR005467; KEGG: dal:Dalk_3917 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12V62 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator rece [...] (488 aa)
Mmah_1954Phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: hypothetical protein; K00902 dolichol kinase; PFAM: phosphatidate cytidylyltransferase; SPTR: Q12VJ4 Putative uncharacterized protein. (196 aa)
Mmah_19592-octaprenylphenol hydroxylase; COGs: COG0661 unusual protein kinase; InterPro IPR004147:IPR000719; KEGG: gsu:GSU1088 ubiquinone biosynthesis protein AarF, putative; PFAM: ABC-1 domain protein; SPTR: Q12VH8 2-octaprenylphenol hydroxylase; PFAM: Phosphotransferase enzyme family; ABC1 family. (559 aa)
tmkCOGs: COG0125 Thymidylate kinase; InterPro IPR000062:IPR018094; KEGG: mmb:Mmol_1138 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Q12VF9 Probable thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. (199 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
ribKCTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (220 aa)
Mmah_0985COGs: COG0703 Shikimate kinase; InterPro IPR000767:IPR000623; KEGG: gbm:Gbem_0200 shikimate kinase; PFAM: shikimate kinase; SPTR: Q466X5 Shikimate kinase; PFAM: Shikimate kinase. (172 aa)
Mmah_0174COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016160; KEGG: rhi:NGR_c25860 putative NADP+ dependent succinate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Q12UQ5 Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family. (436 aa)
Mmah_0135Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (319 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa)
Mmah_0111Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR013656:IPR001610:IPR 000014:IPR000700; KEGG: lch:Lcho_2590 multi-sensor hybrid histidine kinase; PFAM: PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (270 aa)
Mmah_0019Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XC6 ATP-binding region, ATPase-like protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (470 aa)
Mmah_1558COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013656:IPR 013767:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: dal:Dalk_5102 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12ZM3 [...] (1108 aa)
Mmah_0997Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (802 aa)
Mmah_1016Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR001789:IPR013656:IPR013767:IPR000014:IPR 000700; KEGG: ppd:Ppro_3008 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: response regulator receiver; PAS domain containing protein; SPTR: Q12XJ4 Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box. (274 aa)
aroKCOGs: COG1685 shikimate kinase; InterPro IPR013750:IPR006204:IPR010189; KEGG: HSK; HSK (HOMOSERINE KINASE); homoserine kinase; K00872 homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; PRIAM: Shikimate kinase; SPTR: Q12XK2 Shikimate kinase; TIGRFAM: shikimate kinase; PFAM: GHMP kinases N terminal domain; TIGRFAM: shikimate kinase. (285 aa)
Mmah_1063COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR004010:IPR003594:IPR003660:IPR 003661:IPR005467; KEGG: dal:Dalk_1747 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12YI4 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (637 aa)
Mmah_1079COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR008279:IPR002192; KEGG: dat:HRM2_42990 PpsA8; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: B8GDM6 Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (712 aa)
Mmah_1151COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467:IPR000014; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRF [...] (727 aa)
gapCOGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR000173:IPR000846:IPR006436; KEGG: ajs:Ajs_2680 glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating); SPTR: Q12XM4 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domai [...] (334 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
Mmah_1199COGs: COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain; InterPro IPR015285:IPR018934:IPR000687:IPR008266; KEGG: hypothetical protein; K07179 RIO kinase 2; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1; SPTR: Q8PSJ8 Serine/threonine protein kinase; PFAM: RIO1 family; Rio2, N-terminal. (301 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
Mmah_1249COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR003661:IPR 000014:IPR000700:IPR005467; KEGG: xca:xccb100_2028 two-component system sensor histidine kinase-response regulator hybrid protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12Z12 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase [...] (554 aa)
Mmah_1250COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12U10 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (933 aa)
Mmah_1327COGs: COG0630 Type IV secretory pathway VirB11 protein involved in flagella biosynthesis; InterPro IPR001482; KEGG: ilo:IL0903 Flp pilus assembly protein CpaF; PFAM: type II secretion system protein E; SPTR: Q12YP1 Type II secretion system protein E; PFAM: Type II/IV secretion system protein; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type. (717 aa)
cmkCOGs: COG1102 Cytidylate kinase; InterPro IPR011892; KEGG: wbm:Wbm0321 adenylate kinase; PRIAM: Cytidylate kinase; SPTR: Q12ZS5 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase, putative. (179 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
Mmah_1393Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: dat:HRM2_08140 RsbP; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12X67 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (326 aa)
Mmah_1394COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR013767:IPR003594:IPR 003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: dma:DMR_29900 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12X67 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B- [...] (729 aa)
Mmah_1400Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: hypothetical protein; PFAM: phosphatidate cytidylyltransferase; SPTR: Q9UXN7 F420H2-dehydrogenase subunit, putative; PFAM: Cytidylyltransferase family. (214 aa)
Mmah_1503COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR004010:IPR013767:IPR 003594:IPR003660:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: amc:MADE_01755 putative two-component member protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: Q12ZM3 Sens [...] (732 aa)
Mmah_1509Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (179 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (305 aa)
Mmah_1550Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (259 aa)
Mmah_1554COGs: COG0630 Type IV secretory pathway VirB11 protein involved in flagella biosynthesis; InterPro IPR001482; KEGG: dac:Daci_2070 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: Q12TH5 Type II secretion system protein E; PFAM: Type II/IV secretion system protein. (548 aa)
Mmah_0974Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: pca:Pcar_0299 two component sensor histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XR0 Multi-PAS sensor; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (1043 aa)
Mmah_0969Metalloenzyme domain protein; COGs: COG0696 Phosphoglyceromutase; InterPro IPR000917:IPR006124; KEGG: hypothetical protein; K01834 phosphoglycerate mutase; PFAM: metalloenzyme domain protein; sulfatase; SPTR: Q12XR3 Metalloenzyme; PFAM: Metalloenzyme superfamily. (459 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (263 aa)
Mmah_0922COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR018209:IPR001697; KEGG: ppd:Ppro_1852 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q8PYY4 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
Mmah_0912COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: gem:GM21_1199 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kinase [...] (736 aa)
Mmah_0911Putative PAS/PAC sensor protein; InterPro IPR013655:IPR013767:IPR000014:IPR000700; KEGG: ppd:Ppro_2652 histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (486 aa)
Mmah_0908COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013767:IPR003594:IPR000014:IPR 000700:IPR005467; KEGG: nmu:Nmul_A1289 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Q2Y4W7 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (366 aa)
Mmah_0873COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: mfa:Mfla_1656 triphosphoribosyl-dephospho-CoA protein; PFAM: triphosphoribosyl-dephospho-CoA protein; SPTR: Q12ZA3 Triphosphoribosyl-dephospho-CoA protein; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase. (306 aa)
Mmah_0868Putative PAS/PAC sensor protein; InterProIPR013655:IPR003018:IPR013656:IPR013767:IPR 001610:IPR000014:IPR000700; KEGG: pca:Pcar_1343 EAL and GGDEF domain-containing protein; PFAM: PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GAF domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12Z99 Multi-sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; PAS fold; TIGRFAM: PAS domain S-box. (840 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (149 aa)
Mmah_0832Hypothetical protein. (66 aa)
Mmah_0831COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR013656:IPR 013767:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: gur:Gura_2014 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor [...] (962 aa)
Mmah_0821COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: dma:DMR_09640 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12Y17 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (575 aa)
mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (208 aa)
Mmah_0778COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; SPTR: Q12ZD5 Putative uncharacterized protein. (274 aa)
Mmah_1620H4MPT-linked C1 transfer pathway protein; COGs: COG1548 transcriptional regulator/sugar kinase; InterPro IPR002821:IPR002756; KEGG: mfa:Mfla_1649 S-layer protein, putative; PFAM: Hydantoinase/oxoprolinase; SPTR: Q12WE2 Hydantoinase/oxoprolinase; TIGRFAM: H4MPT-linked C1 transfer pathway protein; PFAM: Hydantoinase/oxoprolinase; TIGRFAM: probable H4MPT-linked C1 transfer pathway protein. (320 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (690 aa)
Mmah_0747Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: hha:Hhal_1873 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Q8TNA2 Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2). (503 aa)
Mmah_0670RIO-like kinase; COGs: COG1718 Serine/threonine protein kinase involved in cell cycle control; InterProIPR018934:IPR000687:IPR008266:IPR000719:IPR 018935; KEGG: hypothetical protein; K07178 RIO kinase 1; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; SPTR: Q12XD7 Putative uncharacterized protein; PFAM: RIO1 family. (263 aa)
Mmah_0650Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR008279:IPR002192:IPR000121:IPR018274:IPR 019825:IPR010121; KEGG: gur:Gura_3671 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q12XB9 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding doma [...] (885 aa)
Mmah_0649COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611:IPR002173; KEGG: afr:AFE_0530 carbohydrate kinase, PfkB family; PFAM: PfkB domain protein; SPTR: Q12XB8 Cytidine kinase / inosine-guanosine kinase; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (297 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa)
Mmah_0609COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR003594:IPR003661:IPR 000014:IPR000700:IPR001789:IPR005467; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12TG1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...] (510 aa)
Mmah_0526COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: noc:Noc_2548 carbohydrate kinase, PfkB; PFAM: PfkB domain protein; PRIAM: Adenosine kinase; SPTR: A2WCU5 Sugar kinase; PFAM: pfkB family carbohydrate kinase. (311 aa)
Mmah_0516COGs: COG1829 kinase (sugar kinase superfamily); InterPro IPR006204; PFAM: GHMP kinase; SPTR: Q8PUQ0 Conserved protein; PFAM: GHMP kinases N terminal domain. (291 aa)
Mmah_0508COGs: COG3642 Mn2+-dependent serine/threonine protein kinase; InterPro IPR018934:IPR000719; KEGG: similar to TP53-regulating kinase (p53-related protein kinase) (Nori-2); K08851 TP53 regulating kinase; PFAM: RIO-like kinase; SPTR: Q12WQ8 O-sialoglycoprotein endopeptidase; PFAM: RIO1 family. (189 aa)
Mmah_0496COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (755 aa)
Mmah_0492Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (196 aa)
Mmah_0428COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 013656:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: pmy:Pmen_0835 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TPF6 Sensor protein; TIGR [...] (793 aa)
Mmah_0349Conserved hypothetical protein; COGs: COG0237 Dephospho-CoA kinase; KEGG: hypothetical protein; SPTR: Q8PXA9 UPF0200 protein MM_1313; Belongs to the UPF0200 family. (183 aa)
Mmah_0343COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Q12Z57 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (370 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (294 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (394 aa)
Mmah_0221COGs: COG0527 Aspartokinase; InterPro IPR002912:IPR001048:IPR005260:IPR001341; KEGG: hypothetical protein; K00928 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; PRIAM: Aspartate kinase; SPTR: Q12UL7 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase. (460 aa)
Mmah_0205Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: gme:Gmet_1761 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Q12UM7 Fructose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II. (381 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.