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Mmah_1787 Mmah_1787 Mmah_0146 Mmah_0146 Mmah_0279 Mmah_0279 Mmah_0415 Mmah_0415 Mmah_0416 Mmah_0416 Mmah_0417 Mmah_0417 Mmah_0478 Mmah_0478 Mmah_0498 Mmah_0498 Mmah_0612 Mmah_0612 Mmah_0613 Mmah_0613 Mmah_0614 Mmah_0614 Mmah_0615 Mmah_0615 Mmah_0616 Mmah_0616 Mmah_0632 Mmah_0632 Mmah_0633 Mmah_0633 Mmah_0634 Mmah_0634 Mmah_0635 Mmah_0635 mtd mtd Mmah_0724 Mmah_0724 ftr ftr Mmah_0726 Mmah_0726 Mmah_0739 Mmah_0739 Mmah_0910 Mmah_0910 Mmah_0921 Mmah_0921 Mmah_0950 Mmah_0950 Mmah_0951 Mmah_0951 Mmah_0955 Mmah_0955 Mmah_0970 Mmah_0970 Mmah_1949 Mmah_1949 Mmah_0975 Mmah_0975 Mmah_0977 Mmah_0977 Mmah_1036 Mmah_1036 Mmah_1107 Mmah_1107 mch mch Mmah_1155 Mmah_1155 cdhA cdhA cdhB cdhB cdhC cdhC cdhD cdhD cdhE cdhE Mmah_1269 Mmah_1269 Mmah_1270 Mmah_1270 Mmah_1271 Mmah_1271 Mmah_1285 Mmah_1285 Mmah_1399 Mmah_1399 cbiX cbiX Mmah_1411 Mmah_1411 Mmah_1412 Mmah_1412 Mmah_1413 Mmah_1413 cbiA-2 cbiA-2 mer mer Mmah_1529 Mmah_1529 Mmah_1590 Mmah_1590 Mmah_1591 Mmah_1591 Mmah_1592 Mmah_1592 Mmah_1593 Mmah_1593 Mmah_1596 Mmah_1596 fpoH fpoH Mmah_1633 Mmah_1633 Mmah_1654 Mmah_1654 Mmah_1676 Mmah_1676 Mmah_1681 Mmah_1681 Mmah_1682 Mmah_1682 mtrE mtrE mtrD mtrD mtrC mtrC mtrB mtrB mtrA mtrA mtrF mtrF mtrG mtrG Mmah_1783 Mmah_1783 Mmah_1786 Mmah_1786
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Mmah_1787COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017680; KEGG: geo:Geob_0230 protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q12VV3 CoB--CoM heterodisulfide reductase subunit C; TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C. (161 aa)
Mmah_0146Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017:IPR017900; KEGG: gur:Gura_3039 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q12YM1 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (367 aa)
Mmah_0279Methylamine-specific methylcobalamin:coenzyme M methyltransferase; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257:IPR006360; KEGG: geo:Geob_2543 uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Q12UC0 Methylamine-specific methylcobalamin:coenzyme M methyltransferase; TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family. (342 aa)
Mmah_0415CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (765 aa)
Mmah_0416COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900; KEGG: afr:AFE_2555 iron-sulfur cluster-binding protein; SPTR: Q46B51 Heterodisulfide reductase subunit HdrC. (201 aa)
Mmah_0417COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: dal:Dalk_5067 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q8PZV0 Heterodisulfide reductase subunit HdrB; PFAM: Cysteine-rich domain. (311 aa)
Mmah_0478Aconitase; COGs: COG1048 Aconitase A; InterPro IPR001030:IPR000573:IPR018136:IPR006249; KEGG: hha:Hhal_1406 aconitate hydratase 1; PFAM: aconitate hydratase domain protein; SPTR: Q8PWP8 Aconitate hydratase; TIGRFAM: aconitate hydratase 1; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1. (925 aa)
Mmah_0498Dimethylamine corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: geo:Geob_2541 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Q12W94 Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. (203 aa)
Mmah_0612Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (573 aa)
Mmah_0613COGs: COG4057 Methyl coenzyme M reductase gamma subunit; InterPro IPR003178; PFAM: Methyl-coenzyme M reductase, gamma subunit; PRIAM: Coenzyme-B sulfoethylthiotransferase; SPTR: Q12TF7 Methyl-coenzyme M reductase, gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit. (251 aa)
Mmah_0614COGs: COG4056 Methyl coenzyme M reductase subunit C; InterPro IPR007687; PFAM: Methyl-coenzyme M reductase protein C; SPTR: Q12TF6 Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C. (203 aa)
Mmah_0615COGs: COG4055 Methyl coenzyme M reductase subunit D; InterPro IPR003901; PFAM: Methyl-coenzyme M reductase, protein D; SPTR: Q12TF5 Methyl-coenzyme M reductase, protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase operon protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D. (164 aa)
Mmah_0616COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; PFAM: Methyl-coenzyme M reductase, beta subunit; PRIAM: Coenzyme-B sulfoethylthiotransferase; SPTR: Q12TF4 Methyl-coenzyme M reductase, beta subunit; TIGRFAM: methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit. (434 aa)
Mmah_0632KEGG: dal:Dalk_4840 heterodisulfide reductase subunit C-like protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q12TD9 CoB-CoM heterodisulfide reductase, subunit E. (258 aa)
Mmah_0633CoB-CoM heterodisulfide reductase, subunit D; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017900; KEGG: geo:Geob_0214 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q12TD8 CoB-CoM heterodisulfide reductase, subunit D; PFAM: Cysteine-rich domain. (418 aa)
Mmah_0634Protein of unknown function DUF116; COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: gme:Gmet_3340 hypothetical protein; PFAM: protein of unknown function DUF116; SPTR: Q12TD7 Putative uncharacterized protein; PFAM: Protein of unknown function DUF116. (215 aa)
Mmah_0635Protein of unknown function DUF116; COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: sfu:Sfum_0149 hypothetical protein; PFAM: protein of unknown function DUF116; SPTR: Q12TD6 Putative uncharacterized protein; PFAM: Protein of unknown function DUF116. (211 aa)
mtdMethylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (278 aa)
Mmah_0724Fumarase; COGs: COG0114 Fumarase; InterPro IPR000362:IPR018951:IPR020557; KEGG: gur:Gura_0940 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: C4R559 Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase; fumarate hydratase, class II. (473 aa)
ftrFormylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (297 aa)
Mmah_0726COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058:IPR017900:IPR004489; KEGG: vpa:VP2841 fumarate reductase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Q12ZL3 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (255 aa)
Mmah_0739Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterProIPR018393:IPR003918:IPR003916:IPR001750:IPR 010227; KEGG: tgr:Tgr7_2525 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q12ZH4 Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M. (512 aa)
Mmah_0910COGs: COG5012 cobalamin binding protein; InterPro IPR006158; KEGG: lch:Lcho_2473 cobalamin B12-binding domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: O26227 Conserved protein; PFAM: B12 binding domain. (363 aa)
Mmah_0921COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017900; KEGG: gem:GM21_1382 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Q12YM1 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (358 aa)
Mmah_0950COGs: COG1153 Formylmethanofuran dehydrogenase subunit D; InterPro IPR006657; KEGG: pmr:PMI3577 formate dehydrogenase-H, selenopolypeptide subunit; PFAM: molydopterin dinucleotide-binding region; SPTR: Q12YZ3 Formylmethanofuran dehydrogenase, subunit D; PFAM: Molydopterin dinucleotide binding domain; Cell division protein 48 (CDC48), N-terminal domain. (131 aa)
Mmah_0951COGs: COG1029 Formylmethanofuran dehydrogenase subunit B; InterPro IPR016457; KEGG: mei:Msip34_1506 formylmethanofuran dehydrogenase; PRIAM: Formylmethanofuran dehydrogenase; SPTR: Q12YZ4 Formylmethanofuran dehydrogenase, subunit B; TIGRFAM: formylmethanofuran dehydrogenase subunit B; TIGRFAM: formylmethanofuran dehydrogenase subunit B. (415 aa)
Mmah_0955CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (784 aa)
Mmah_0970Methanol-specific methylcobalamin: coenzyme M methyltransferase; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257:IPR001969:IPR006360; KEGG: geo:Geob_2543 uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Q12XR2 Methanol-specific methylcobalamin: coenzyme M methyltransferase; TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family. (339 aa)
Mmah_1949Thiol-driven fumarate reductase, iron-sulfur protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017:IPR017900; KEGG: sat:SYN_01643 Fe-S oxidoreductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q8PXD1 Fe-S oxidoreductase; PFAM: Cysteine-rich domain. (353 aa)
Mmah_0975Methanol corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation; PFAM: Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: Q12XQ9 Methanol corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain. (254 aa)
Mmah_0977Methanol corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: dma:DMR_21130 methionine synthase; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Q12XQ7 Methanol corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain. (256 aa)
Mmah_1036Metallophosphoesterase; COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: dol:Dole_2142 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Q8PU24 Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase. (216 aa)
Mmah_1107COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557:IPR001236:IPR011275; KEGG: dol:Dole_2374 malate dehydrogenase, NAD-dependent; PFAM: Lactate/malate dehydrogenase; PRIAM: Malate dehydrogenase; SPTR: Q8PVJ7 Malate dehydrogenase; TIGRFAM: malate dehydrogenase, NAD-dependent; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent; Belongs to the LDH/MDH superfamily. (307 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (319 aa)
Mmah_1155Monomethylamine corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: dat:HRM2_07470 MtmC; PFAM: Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: Q12XM8 Monomethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. (217 aa)
cdhAacetyl-CoA decarbonylase/synthase alpha subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (801 aa)
cdhBacetyl-CoA decarbonylase/synthase epsilon subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation. (170 aa)
cdhCacetyl-CoA decarbonylase/synthase beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (465 aa)
cdhDacetyl-CoA decarbonylase/synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. (439 aa)
cdhEacetyl-CoA decarbonylase/synthase gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (470 aa)
Mmah_1269COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR002489:IPR017550; KEGG: mca:MCA2857 formylmethanofurane dehydrogenase subunit, putative; PFAM: glutamate synthase alpha subunit domain protein; PRIAM: Formylmethanofuran dehydrogenase; SPTR: Q12Z39 Formylmethanofuran dehydrogenase, subunit C; TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C. (269 aa)
Mmah_1270COGs: COG1153 Formylmethanofuran dehydrogenase subunit D; InterPro IPR006657; PFAM: molydopterin dinucleotide-binding region; SPTR: Q12Z40 Formylmethanofuran dehydrogenase, subunit D; PFAM: Molydopterin dinucleotide binding domain. (129 aa)
Mmah_1271COGs: COG1029 Formylmethanofuran dehydrogenase subunit B; InterPro IPR006656:IPR016457; KEGG: mca:MCA2860 formylmethanofuran dehydrogenase; PFAM: molybdopterin oxidoreductase; SPTR: Q12Z41 Formylmethanofuran dehydrogenase, subunit B; TIGRFAM: formylmethanofuran dehydrogenase subunit B; PFAM: Molybdopterin oxidoreductase; TIGRFAM: formylmethanofuran dehydrogenase subunit B. (435 aa)
Mmah_1285COGs: COG4063 Tetrahydromethanopterin S-methyltransferase subunit A; InterPro IPR013340; KEGG: dar:Daro_2280 tetrahydromethanopterin S-methyltransferase subunit A; PFAM: Tetrahydromethanopterin S-methyltransferase subunit A domain protein; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: Q46BT7 Tetrahydromethanopterin S-methyltransferase, subunit A; PFAM: Tetrahydromethanopterin S-methyltransferase, subunit A. (215 aa)
Mmah_1399InterPro IPR008031; PFAM: Monomethylamine methyltransferase MtmB; SPTR: P58865 Monomethylamine methyltransferase mtmB1; PFAM: Monomethylamine methyltransferase MtmB. (457 aa)
cbiXSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (131 aa)
Mmah_1411Mur ligase middle domain protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR013221; KEGG: azo:azo0882 UDP-N-acetylmuramoylalanine-D-glutamate ligase; PFAM: Mur ligase middle domain protein; SPTR: Q12X55 Putative uncharacterized protein; PFAM: Mur ligase middle domain. (444 aa)
Mmah_1412Methanogenesis marker 13 metalloprotein; COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR017675; KEGG: geo:Geob_2466 nitrogenase; SPTR: Q8PZH8 Conserved protein; TIGRFAM: methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: putative methanogenesis marker 13 metalloprotein. (369 aa)
Mmah_1413Mo-nitrogenase iron protein subunit NifH; COGs: COG1348 Nitrogenase subunit NifH (ATPase); InterPro IPR000392; KEGG: sfu:Sfum_1019 nitrogenase reductase; PFAM: NifH/frxC-family protein; PRIAM: Nitrogenase; SPTR: Q12X53 Nitrogenase iron protein subunit NifH; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein. (265 aa)
cbiA-2Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or amm [...] (481 aa)
merMethylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (328 aa)
Mmah_1529PFAM: Protein of unknown function DUF116. (243 aa)
Mmah_1590COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR003916:IPR001750:IPR010096; KEGG: glo:Glov_3125 proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q12WH0 F420H2 dehydrogenase subunit N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N. (483 aa)
Mmah_1591F420H2 dehydrogenase subunit M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918:IPR001750:IPR010227; KEGG: net:Neut_0934 NADH dehydrogenase subunit M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q12WG9 F420H2 dehydrogenase subunit M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: LPXTG-motif cell wall anchor domain; proton-translocating NADH-quinone oxidoreductase, chain M. (495 aa)
Mmah_1592F420H2 dehydrogenase subunit L; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR018393:IPR003916:IPR001750:IPR001516:IPR 003945; KEGG: oan:Oant_2412 NADH dehydrogenase subunit L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Q12WG8 F420H2 dehydrogenase subunit L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone (complex [...] (670 aa)
Mmah_1593F420H2 dehydrogenase subunit K; COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: gur:Gura_4234 NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: Q12WG7 F420H2 dehydrogenase subunit K; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L. (100 aa)
Mmah_1596COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR001080:IPR001450:IPR017900; KEGG: glo:Glov_3130 NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q12WG6 F420H2 dehydrogenase subunit I. (137 aa)
fpoHF420H2 dehydrogenase subunit H; FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (342 aa)
Mmah_1633Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR000759:IPR013027:IPR000103:IPR001327:IPR 006004; KEGG: sat:SYN_00606 glutamate synthase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Q12WD0 Sulfide dehydrogenase (Flavoprotein) subunit SudA; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric. (458 aa)
Mmah_1654Acetyl coenzyme A synthetase (ADP forming), alpha domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR011761:IPR014089; KEGG: dma:DMR_20040 CoA-binding domain protein; PFAM: CoA-binding domain protein; SPTR: Q12WB1 Acyl-CoA synthetase; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain. (697 aa)
Mmah_1676Dimethylamine corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: geo:Geob_2541 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Q12W94 Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain. (203 aa)
Mmah_1681COGs: COG5598 Trimethylamine:corrinoid methyltransferase; KEGG: dol:Dole_1111 trimethylamine methyltransferase; SPTR: Q12TR2 Trimethylamine methyltransferase mttB; PFAM: Trimethylamine methyltransferase (MTTB). (147 aa)
Mmah_1682COGs: COG5598 Trimethylamine:corrinoid methyltransferase; InterPro IPR012740; KEGG: dat:HRM2_15930 MttB6; SPTR: Q8TS73 Trimethylamine methyltransferase mttB2; TIGRFAM: trimethylamine; PFAM: Trimethylamine methyltransferase (MTTB); TIGRFAM: trimethylamine:corrinoid methyltransferase. (333 aa)
mtrETetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (302 aa)
mtrDTetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (239 aa)
mtrCTetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (271 aa)
mtrBTetrahydromethanopterin S-methyltransferase, subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (107 aa)
mtrATetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (240 aa)
mtrFTetrahydromethanopterin S-methyltransferase, subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (75 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (77 aa)
Mmah_1783COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: Q12VV1 Tetrahydromethanopterin S-methyltransferase, subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. (318 aa)
Mmah_1786COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017:IPR017678; KEGG: dal:Dalk_5067 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Q12VV2 CoB--CoM heterodisulfide reductase subunit B; TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; PFAM: Cysteine-rich domain; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit B. (297 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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