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Mmah_1169 | Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: dat:HRM2_16760 AcsF; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12XL4 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (251 aa) | ||||
tfe | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (164 aa) | ||||
Mmah_1202 | Glutaredoxin; InterPro IPR006662:IPR002109; KEGG: tgr:Tgr7_3133 hypothetical protein; PFAM: glutaredoxin; SPTR: Q12ZK6 Putative uncharacterized protein; PFAM: Thioredoxin. (80 aa) | ||||
eif6 | Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (216 aa) | ||||
Mmah_1249 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR003661:IPR 000014:IPR000700:IPR005467; KEGG: xca:xccb100_2028 two-component system sensor histidine kinase-response regulator hybrid protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12Z12 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase [...] (554 aa) | ||||
Mmah_1250 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12U10 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (933 aa) | ||||
Mmah_1294 | Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: swd:Swoo_4387 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: A0Y627 Putative arsenic resistance operon regulator; PFAM: Bacterial regulatory protein, arsR family. (133 aa) | ||||
Mmah_1368 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: hha:Hhal_1901 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12TD0 Response regulator receiver; PFAM: Response regulator receiver domain. (123 aa) | ||||
Mmah_1385 | Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: sfu:Sfum_4099 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12X77 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (255 aa) | ||||
Mmah_1393 | Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: dat:HRM2_08140 RsbP; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12X67 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (326 aa) | ||||
Mmah_1394 | COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR013767:IPR003594:IPR 003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: dma:DMR_29900 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12X67 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B- [...] (729 aa) | ||||
Mmah_1426 | Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: wsu:WS1168 hypothetical protein; PFAM: helix-turn-helix HxlR type; SPTR: Q12VY6 Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix. (124 aa) | ||||
Mmah_1455 | Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: dma:DMR_44420 putative DNA-binding protein; SMART: Transcription regulator, AsnC-type; SPTR: Q12WM2 Transcriptional regulator, AsnC family. (151 aa) | ||||
Mmah_1456 | COGs: COG1522 Transcriptional regulators; KEGG: dol:Dole_2996 AsnC family transcriptional regulator; SPTR: Q12WM3 Transcriptional regulator, AsnC family. (156 aa) | ||||
Mmah_1500 | Transcriptional regulator, ArsR family; COGs: COG4742 transcriptional regulator protein; InterPro IPR013561; PFAM: Domain of unknown function DUF1724; SPTR: Q12WY6 Transcriptional regulator, ArsR family; PFAM: Domain of unknown function (DUF1724). (271 aa) | ||||
Mmah_1501 | COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: mmb:Mmol_0644 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q8PSR9 Putative transcriptional regulator; PFAM: Response regulator receiver domain. (140 aa) | ||||
Mmah_1503 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR004010:IPR013767:IPR 003594:IPR003660:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: amc:MADE_01755 putative two-component member protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: Q12ZM3 Sens [...] (732 aa) | ||||
Mmah_1530 | KEGG: hypothetical protein; K04646 clathrin, heavy polypeptide; SPTR: Q8TPU3 Predicted protein. (81 aa) | ||||
Mmah_1548 | Protein of unknown function DUF52; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: gsu:GSU1830 hypothetical protein; PFAM: protein of unknown function DUF52; SPTR: Q12TI1 UPF0103 protein Mbur_2394; PFAM: Memo-like protein; Belongs to the MEMO1 family. (265 aa) | ||||
Mmah_1558 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013656:IPR 013767:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: dal:Dalk_5102 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12ZM3 [...] (1108 aa) | ||||
Mmah_1562 | Putative transcriptional regulator; InterPro IPR001845; SMART: regulatory protein ArsR; SPTR: Q46C08 Putative uncharacterized protein. (114 aa) | ||||
ef1b | Translation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) | ||||
Mmah_1643 | Transcriptional regulator, ArsR family; InterPro IPR001845; KEGG: atc:AGR_C_3686 hypothetical protein; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Q12XD8 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (171 aa) | ||||
Mmah_1669 | Transcriptional regulator, MarR family; COGs: COG1497 transcriptional regulator protein; InterPro IPR000835:IPR013196:IPR001808; PFAM: Helix-turn-helix type 11 domain protein; regulatory protein MarR; SMART: regulatory protein Crp; SPTR: Q12W99 Transcriptional regulator, Crp/Fnr family; PFAM: HTH domain. (262 aa) | ||||
Mmah_1698 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (170 aa) | ||||
dacZ | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (289 aa) | ||||
Mmah_1706 | COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029:IPR011488; KEGG: eukaryotic translation initiation factor 2 subunit 1; K03237 translation initiation factor eIF-2 alpha subunit; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: Q12W65 Translation initiation factor 2 subunit alpha (AeIF-2a); PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. (265 aa) | ||||
eif2b | Translation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (202 aa) | ||||
Mmah_1741 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (327 aa) | ||||
tbp | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa) | ||||
Mmah_1830 | InterPro IPR001845; KEGG: dde:Dde_0747 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Q46EY1 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (115 aa) | ||||
Mmah_1841 | Thioesterase superfamily protein; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683:IPR003736; KEGG: afw:Anae109_3719 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Q12VR5 Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD. (134 aa) | ||||
Mmah_1843 | Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gur:Gura_2117 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12VR3 Response regulator receiver; PFAM: Response regulator receiver domain. (141 aa) | ||||
eif5a | Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (127 aa) | ||||
Mmah_1863 | COGs: COG1326 Uncharacterized Zn-finger protein; SPTR: Q12UU9 Putative uncharacterized protein. (217 aa) | ||||
Mmah_1865 | COGs: COG0704 Phosphate uptake regulator; InterPro IPR007159:IPR008170; KEGG: dat:HRM2_02440 PhoU2; PFAM: PhoU family protein; SpoVT/AbrB domain protein; SPTR: Q8TR05 Putative uncharacterized protein; PFAM: PhoU domain; SpoVT / AbrB like domain. (337 aa) | ||||
Mmah_1872 | Putative signal transduction protein with CBS domains; COGs: COG2524 transcriptional regulator protein; InterPro IPR013196:IPR000644:IPR000944:IPR005104; KEGG: swp:swp_3318 cyclic nucleotide-binding:CBS:putative nucleotidyltransferase DUF294; PFAM: Protein of unknown function DUF293; CBS domain containing protein; Helix-turn-helix type 11 domain protein; protein of unknown function UPF0074; SMART: CBS domain containing protein; SPTR: Q12UV7 Putative uncharacterized protein; PFAM: CBS domain; Domain of unknown function. (291 aa) | ||||
Mmah_1887 | Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR007167:IPR001367; KEGG: dat:HRM2_42740 TroR; PFAM: FeoA family protein; iron dependent repressor; SMART: iron dependent repressor; SPTR: Q12UX2 Iron dependent repressor; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (229 aa) | ||||
Mmah_1917 | Transcriptional regulator, XRE family; COGs: COG1395 transcriptional regulator protein; InterPro IPR001387; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Q12V29 Putative HTH-type transcriptional regulatory protein Mbur_1811; PFAM: Helix-turn-helix. (319 aa) | ||||
Mmah_1930 | KEGG: abpD; actin binding protein; SPTR: Q467T2 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (254 aa) | ||||
Mmah_1936 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR001327:IPR004099:IPR 012999; KEGG: bpd:BURPS668_A0283 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Q12V54 Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (479 aa) | ||||
Mmah_1948 | Multi-sensor signal transduction histidine kinase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR001789:IPR013767:IPR013656:IPR003661:IPR 000014:IPR000700:IPR005467; KEGG: dal:Dalk_3917 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12V62 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator rece [...] (488 aa) | ||||
Mmah_2000 | DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: gur:Gura_0409 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: A7I6V0 DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain. (99 aa) | ||||
Mmah_0012 | COGs: COG3276 Selenocysteine-specific translation elongation factor; InterPro IPR004161; KEGG: dar:Daro_1810 selenocysteine-specific translation elongation factor SelB; PFAM: elongation factor Tu domain 2 protein; SPTR: Q12V79 Elongation factor Tu, domain 2; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain. (346 aa) | ||||
Mmah_0027 | Transcriptional regulator, ArsR family; InterPro IPR001845; PFAM: regulatory protein ArsR; SPTR: Q12WV3 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (230 aa) | ||||
Mmah_0097 | InterPro IPR006339; SPTR: Q12TS3 Transcriptional regulator, AbrB family; TIGRFAM: transcriptional regulator, AbrB family; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family. (91 aa) | ||||
Mmah_0111 | Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR013656:IPR001610:IPR 000014:IPR000700; KEGG: lch:Lcho_2590 multi-sensor hybrid histidine kinase; PFAM: PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (270 aa) | ||||
Mmah_0124 | DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: gem:GM21_3743 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: Q8TNZ6 Nucleotidyltransferase; PFAM: Nucleotidyltransferase domain. (101 aa) | ||||
spt5 | LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa) | ||||
rpl1 | LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) | ||||
Mmah_0215 | Transcriptional regulator, XRE family; COGs: COG1476 transcriptional regulator protein; InterPro IPR001387; KEGG: shl:Shal_4180 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Q12Z31 Transcriptional regulator, XRE family; PFAM: Helix-turn-helix. (64 aa) | ||||
Mmah_0231 | Hypothetical protein; SPTR: Q12UK7 Putative uncharacterized protein. (113 aa) | ||||
Mmah_0246 | Transcriptional regulator, TrmB; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR002831; KEGG: sat:SYN_00652 MarR family transcriptional regulator; PFAM: regulatory protein MarR; transcriptional regulator TrmB; SMART: regulatory protein MarR; SPTR: Q8TP67 Transcriptional regulator, MarR family; PFAM: MarR family. (146 aa) | ||||
Mmah_0252 | Deoxyribonuclease/rho motif-related TRAM; COGs: COG3269 RNA-binding protein contains TRAM domain; InterPro IPR002792; KEGG: dol:Dole_1585 RNA methyltransferase; PFAM: deoxyribonuclease/rho motif-related TRAM; SPTR: Q12YA1 Putative uncharacterized protein; PFAM: TRAM domain. (67 aa) | ||||
Mmah_0257 | Putative transcriptional regulator, CopG family; SPTR: Q12UF9 Putative nickel-responsive regulator; PFAM: NikR C terminal nickel binding domain. (40 aa) | ||||
prf1 | Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa) | ||||
Mmah_0258 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR002145:IPR014864; KEGG: sat:SYN_00477 nickel-responsive regulator; PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; SPTR: Q12UF9 Putative nickel-responsive regulator; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain. (94 aa) | ||||
Mmah_0261 | COGs: COG2522 transcriptional regulator protein; SPTR: Q12UF2 Putative uncharacterized protein; PFAM: Helix-turn-helix. (119 aa) | ||||
Mmah_0262 | COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950:IPR005872; KEGG: hch:HCH_00188 translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Q12UF1 Protein translation factor SUI1 homolog; TIGRFAM: translation initiation factor SUI1; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic; Belongs to the SUI1 family. (102 aa) | ||||
Mmah_0269 | Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR000835:IPR001367; KEGG: tcx:Tcr_0904 iron dependent repressor; PFAM: iron dependent repressor; regulatory protein MarR; SMART: iron dependent repressor; SPTR: Q12UD0 Iron dependent repressor; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (139 aa) | ||||
Mmah_0287 | Transcriptional regulator, TrmB; COGs: COG3355 transcriptional regulator protein; InterPro IPR002831; PFAM: transcriptional regulator TrmB; SPTR: Q12UA5 Transcriptional regulator TrmB; PFAM: Sugar-specific transcriptional regulator TrmB. (127 aa) | ||||
Mmah_0297 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: pla:Plav_2814 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12U95 Response regulator receiver protein; PFAM: Response regulator receiver domain. (121 aa) | ||||
Mmah_0301 | Transcriptional regulator, XRE family; COGs: COG1813 transcription factor homolog of eukaryotic MBF1; InterPro IPR001387:IPR004451; KEGG: hypothetical protein; K03627 putative transcription factor; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Q12U90 Transcriptional regulator, XRE family; PFAM: Helix-turn-helix; TIGRFAM: conserved hypothetical protein TIGR00270. (160 aa) | ||||
Mmah_0343 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Q12Z57 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (370 aa) | ||||
Mmah_0346 | Putative transcriptional regulator, CopG/Arc/MetJ family; SPTR: Q8TUL1 Putative uncharacterized protein. (56 aa) | ||||
Mmah_0365 | Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: aeh:Mlg_1602 multiple antibiotic resistance (MarC)-related proteins; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: Q8TKJ4 Multiple antibiotic resistance protein (MarC-like protein); PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427. (213 aa) | ||||
Mmah_0369 | COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: mmb:Mmol_0499 two component transcriptional regulator PhoB, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12U26 Response regulator receiver; PFAM: Response regulator receiver domain. (355 aa) | ||||
Mmah_0007 | Protein of unknown function DUF1294; COGs: COG3326 membrane protein; InterPro IPR010718; KEGG: hps:HPSH_01780 hypothetical protein; PFAM: protein of unknown function DUF1294; SPTR: Q12V96 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1294). (89 aa) | ||||
Mmah_0383 | COGs: COG2522 transcriptional regulator protein; SPTR: Q12Z32 Putative uncharacterized protein. (111 aa) | ||||
pcn | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (245 aa) | ||||
Mmah_0389 | COGs: COG1594 DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS; InterPro IPR001529:IPR001222:IPR019761:IPR006288; KEGG: hypothetical protein; K03019 DNA-directed RNA polymerase III subunit C11; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SPTR: Q12U17 DNA-directed RNA polymerase, subunit M; TIGRFAM: transcription factor S; PFAM: RNA polymerases M/15 Kd subunit; Transcription factor S-II (TFIIS); TIGRFAM: transcription factor S, archaeal. (104 aa) | ||||
Mmah_0399 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000103:IPR000815:IPR001327:IPR 004099:IPR012999; KEGG: gbm:Gbem_3786 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Q46EZ2 Glutathione reductase (NADPH); PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, [...] (447 aa) | ||||
Mmah_0428 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 013656:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: pmy:Pmen_0835 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TPF6 Sensor protein; TIGR [...] (793 aa) | ||||
Mmah_0446 | Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR007167:IPR001367; KEGG: gem:GM21_2623 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: O29994 Iron-dependent repressor (DesR); PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain. (218 aa) | ||||
eif1a | S1 IF1 family protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (70 aa) | ||||
Mmah_0484 | Transcriptional regulator, MarR family; InterPro IPR000835; KEGG: ara:Arad_4079 transcriptional regulator protein; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Q12TU2 Transcriptional regulator, MarR family; PFAM: MarR family. (156 aa) | ||||
eif2g | Translation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa) | ||||
spt4 | DNA-directed RNA polymerase, subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (61 aa) | ||||
Mmah_0495 | Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gur:Gura_2117 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12TT1 Response regulator receiver; PFAM: Response regulator receiver domain. (131 aa) | ||||
Mmah_0496 | COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (755 aa) | ||||
rlmE | 23S rRNA Um-2552 2'-O-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (264 aa) | ||||
nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (141 aa) | ||||
fusA | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (730 aa) | ||||
tuf | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa) | ||||
Mmah_0540 | KEGG: nis:NIS_1848 hypothetical protein; SPTR: Q12WT5 Putative uncharacterized protein; PFAM: Sugar-specific transcriptional regulator TrmB. (66 aa) | ||||
Mmah_0546 | 4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0348 Polyferredoxin; InterPro IPR001450:IPR017900; KEGG: gsu:GSU0729 iron-sulfur cluster-binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q12WW0 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain. (205 aa) | ||||
Mmah_0547 | Transcriptional regulator, TrmB; COGs: COG3355 transcriptional regulator protein; InterPro IPR002831; PFAM: transcriptional regulator TrmB; SPTR: Q12WW1 Putative uncharacterized protein; PFAM: Sugar-specific transcriptional regulator TrmB. (115 aa) | ||||
Mmah_0609 | COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR003594:IPR003661:IPR 000014:IPR000700:IPR001789:IPR005467; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12TG1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...] (510 aa) | ||||
Mmah_0623 | COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR003142:IPR013196:IPR004143:IPR004408; KEGG: gur:Gura_2817 biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; Helix-turn-helix type 11 domain protein; biotin protein ligase domain protein; SPTR: Q8PVX6 Biotin--[acetyl-COA-carboxylase] synthetase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain. (322 aa) | ||||
dphB | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (268 aa) | ||||
tfb | Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa) | ||||
Mmah_0660 | InterPro IPR005357; PFAM: protein of unknown function UPF0150; SPTR: Q12W24 Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150). (78 aa) | ||||
Mmah_0672 | InterPro IPR001845; KEGG: abu:Abu_1860 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Q12TH0 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (113 aa) | ||||
Mmah_0752 | COGs: COG0704 Phosphate uptake regulator; InterPro IPR007159:IPR008170; KEGG: bbr:BB3407 putative transport protein; PFAM: PhoU family protein; SpoVT/AbrB domain protein; SPTR: Q2Y4E8 Putative PhoU family protein; PFAM: PhoU domain; SpoVT / AbrB like domain. (347 aa) | ||||
Mmah_0759 | Protein of unknown function UPF0029; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498:IPR015269; KEGG: prw:PsycPRwf_0035 hypothetical protein; PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; SPTR: Q12W19 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: conserved hypothetical protein TIGR00257. (199 aa) | ||||
Mmah_0762 | COGs: COG3432 transcriptional regulator protein; SPTR: Q12Z00 Putative uncharacterized protein. (82 aa) | ||||
Mmah_0774 | Hypothetical protein; SPTR: Q12ZD9 Putative uncharacterized protein. (114 aa) | ||||
Mmah_0778 | COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; SPTR: Q12ZD5 Putative uncharacterized protein. (274 aa) | ||||
Mmah_0812 | InterPro IPR001845:IPR005149; KEGG: xfn:XfasM23_1996 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; transcriptional regulator PadR family protein; SMART: regulatory protein ArsR; SPTR: Q8PSA9 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (105 aa) | ||||
Mmah_0821 | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: dma:DMR_09640 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12Y17 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (575 aa) | ||||
Mmah_0831 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR013656:IPR 013767:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: gur:Gura_2014 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor [...] (962 aa) | ||||
Mmah_0832 | Hypothetical protein. (66 aa) | ||||
infB | Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (593 aa) | ||||
Mmah_0868 | Putative PAS/PAC sensor protein; InterProIPR013655:IPR003018:IPR013656:IPR013767:IPR 001610:IPR000014:IPR000700; KEGG: pca:Pcar_1343 EAL and GGDEF domain-containing protein; PFAM: PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GAF domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12Z99 Multi-sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; PAS fold; TIGRFAM: PAS domain S-box. (840 aa) | ||||
Mmah_0875 | Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (216 aa) | ||||
Mmah_0911 | Putative PAS/PAC sensor protein; InterPro IPR013655:IPR013767:IPR000014:IPR000700; KEGG: ppd:Ppro_2652 histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (486 aa) | ||||
Mmah_0912 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: gem:GM21_1199 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kinase [...] (736 aa) | ||||
Mmah_0974 | Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: pca:Pcar_0299 two component sensor histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XR0 Multi-PAS sensor; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (1043 aa) | ||||
Mmah_1016 | Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR001789:IPR013656:IPR013767:IPR000014:IPR 000700; KEGG: ppd:Ppro_3008 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: response regulator receiver; PAS domain containing protein; SPTR: Q12XJ4 Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box. (274 aa) | ||||
Mmah_1021 | COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: dat:HRM2_33390 two-component transcriptional regulatory protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12XJ9 Response regulator receiver; PFAM: Response regulator receiver domain. (285 aa) | ||||
Mmah_1063 | COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR004010:IPR003594:IPR003660:IPR 003661:IPR005467; KEGG: dal:Dalk_1747 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12YI4 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (637 aa) | ||||
Mmah_1099 | Deoxyribonuclease/rho motif-related TRAM; COGs: COG3269 RNA-binding protein contains TRAM domain; InterPro IPR002792; KEGG: sat:SYN_01023 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; PFAM: deoxyribonuclease/rho motif-related TRAM; SPTR: Q12Z20 Putative uncharacterized protein; PFAM: TRAM domain. (63 aa) | ||||
Mmah_1130 | COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: dvm:DvMF_2677 response regulator receiver sensor hybrid histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q8PSW9 Transcriptional regulator; PFAM: Response regulator receiver domain. (140 aa) | ||||
Mmah_1141 | Transcriptional regulator, ArsR family; COGs: COG1719 hydrocarbon binding protein (contains V4R domain); InterPro IPR004096:IPR001845; KEGG: dds:Ddes_0419 4-vinyl reductase 4VR; PFAM: 4-vinyl reductase 4VR; regulatory protein ArsR; SPTR: Q12Y49 4-vinyl reductase, 4VR; PFAM: Bacterial regulatory protein, arsR family; V4R domain. (244 aa) | ||||
Mmah_1146 | InterPro IPR013096:IPR001387; KEGG: ppd:Ppro_0474 XRE family transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: A9A664 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix. (190 aa) | ||||
Mmah_1150 | Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gur:Gura_2117 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12XN2 Response regulator receiver; PFAM: Response regulator receiver domain. (129 aa) | ||||
Mmah_1151 | COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467:IPR000014; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRF [...] (727 aa) |