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tyrS tyrS Mmah_1772 Mmah_1772 Mmah_1788 Mmah_1788 Mmah_1795 Mmah_1795 rad50 rad50 smc smc Mmah_1824 Mmah_1824 Mmah_1832 Mmah_1832 Mmah_1835 Mmah_1835 Mmah_1836 Mmah_1836 Mmah_1856 Mmah_1856 Mmah_1866 Mmah_1866 Mmah_1869 Mmah_1869 Mmah_1871 Mmah_1871 hisE hisE nnrD nnrD prs prs Mmah_1886 Mmah_1886 lysS lysS Mmah_1903 Mmah_1903 Mmah_1904 Mmah_1904 Mmah_1908 Mmah_1908 Mmah_1913 Mmah_1913 tiaS tiaS nadE nadE Mmah_1920 Mmah_1920 Mmah_1939 Mmah_1939 Mmah_1941 Mmah_1941 Mmah_1959 Mmah_1959 Mmah_1961 Mmah_1961 Mmah_0001 Mmah_0001 argS argS Mmah_0011 Mmah_0011 Mmah_0012 Mmah_0012 purP purP Mmah_0047 Mmah_0047 Mmah_0048 Mmah_0048 glmS glmS Mmah_0124 Mmah_0124 pyrH pyrH Mmah_0134 Mmah_0134 Mmah_0135 Mmah_0135 Mmah_0139 Mmah_0139 Mmah_0144 Mmah_0144 Mmah_0160 Mmah_0160 metG metG ftsZ ftsZ Mmah_0189 Mmah_0189 Mmah_0190 Mmah_0190 Mmah_0191 Mmah_0191 Mmah_0193 Mmah_0193 Mmah_0198 Mmah_0198 Mmah_0200 Mmah_0200 Mmah_0201 Mmah_0201 Mmah_0208 Mmah_0208 Mmah_0216 Mmah_0216 Mmah_0217 Mmah_0217 purM purM Mmah_0225 Mmah_0225 Mmah_0229 Mmah_0229 Mmah_0232 Mmah_0232 guaAA guaAA radA radA Mmah_0251 Mmah_0251 purC purC purL purL Mmah_0281 Mmah_0281 pylS pylS Mmah_0295 Mmah_0295 pan pan Mmah_0316 Mmah_0316 radB radB thiL thiL Mmah_0324 Mmah_0324 Mmah_0326 Mmah_0326 Mmah_0330 Mmah_0330 Mmah_0332 Mmah_0332 Mmah_0333 Mmah_0333 Mmah_0335 Mmah_0335 Mmah_0340 Mmah_0340 Mmah_0343 Mmah_0343 Mmah_0349 Mmah_0349 valS valS alaS alaS Mmah_0375 Mmah_0375 moaA moaA cbiA cbiA Mmah_0394 Mmah_0394 groL groL groS groS Mmah_0398 Mmah_0398 rfcL rfcL Mmah_0411 Mmah_0411 Mmah_0426 Mmah_0426 rtcB rtcB Mmah_1020 Mmah_1020 Mmah_0448 Mmah_0448 Mmah_0449 Mmah_0449 uvrB uvrB Mmah_0467 Mmah_0467 eif2g eif2g Mmah_0495 Mmah_0495 top6B top6B top6A top6A Mmah_0508 Mmah_0508 Mmah_0515 Mmah_0515 Mmah_0516 Mmah_0516 Mmah_0519 Mmah_0519 Mmah_0522 Mmah_0522 Mmah_0529 Mmah_0529 Mmah_0530 Mmah_0530 fusA fusA tuf tuf cca cca hel308 hel308 lig lig uvrA uvrA Mmah_0594 Mmah_0594 Mmah_0596 Mmah_0596 purD purD proB proB Mmah_0619 Mmah_0619 Mmah_0622 Mmah_0622 Mmah_0628 Mmah_0628 Mmah_0638 Mmah_0638 Mmah_0641 Mmah_0641 Mmah_0644 Mmah_0644 Mmah_0650 Mmah_0650 Mmah_0651 Mmah_0651 Mmah_0661 Mmah_0661 Mmah_0670 Mmah_0670 sepS sepS Mmah_0689 Mmah_0689 glyS glyS sat sat Mmah_0706 Mmah_0706 Mmah_0744 Mmah_0744 Mmah_0746 Mmah_0746 ppk ppk Mmah_0778 Mmah_0778 mptE mptE ileS ileS proS proS Mmah_0828 Mmah_0828 srp54 srp54 aspS aspS gyrB gyrB gyrA gyrA Mmah_0856 Mmah_0856 infB infB ndk ndk Mmah_0873 Mmah_0873 pstB pstB Mmah_0883 Mmah_0883 Mmah_0900 Mmah_0900 Mmah_0922 Mmah_0922 Mmah_0929 Mmah_0929 thiM thiM gatE gatE carA carA carB carB argG argG Mmah_0966 Mmah_0966 Mmah_0972 Mmah_0972 Mmah_0985 Mmah_0985 Mmah_0997 Mmah_0997 Mmah_0999 Mmah_0999 Mmah_1000 Mmah_1000 Mmah_1002 Mmah_1002 Mmah_1006 Mmah_1006 Mmah_1009 Mmah_1009 Mmah_1019 Mmah_1019 aroK aroK Mmah_1045 Mmah_1045 Mmah_1050 Mmah_1050 Mmah_1073 Mmah_1073 cysS cysS rtcA rtcA Mmah_1077 Mmah_1077 Mmah_1087 Mmah_1087 lig-2 lig-2 rimK rimK Mmah_1100 Mmah_1100 ribL ribL Mmah_1130 Mmah_1130 Mmah_1150 Mmah_1150 nadK nadK Mmah_1169 Mmah_1169 gatB gatB gatA gatA gatC gatC tmk tmk cetZ cetZ lolD lolD Mmah_2000 Mmah_2000 Mmah_2008 Mmah_2008 Mmah_2009 Mmah_2009 Mmah_2012 Mmah_2012 mutL mutL mutS mutS Mmah_2020 Mmah_2020 Mmah_2021 Mmah_2021 Mmah_2026 Mmah_2026 Mmah_1181 Mmah_1181 Mmah_1188 Mmah_1188 mobA mobA Mmah_1199 Mmah_1199 ftsY ftsY purA purA Mmah_1224 Mmah_1224 guaAB guaAB argB argB ftsZ-2 ftsZ-2 Mmah_1260 Mmah_1260 engB engB Mmah_1278 Mmah_1278 pheT pheT purQ purQ purS purS Mmah_1337 Mmah_1337 cmk cmk adk adk Mmah_1385 Mmah_1385 Mmah_1391 Mmah_1391 Mmah_1392 Mmah_1392 gatD gatD Mmah_1404 Mmah_1404 Mmah_1411 Mmah_1411 Mmah_1412 Mmah_1412 Mmah_1413 Mmah_1413 cbiA-2 cbiA-2 hflX hflX Mmah_1424 Mmah_1424 atpD atpD atpB atpB atpA atpA atpF atpF atpC atpC atpE atpE gltX gltX serS serS Mmah_1479 Mmah_1479 hisS hisS Mmah_1509 Mmah_1509 Mmah_1511 Mmah_1511 Mmah_1537 Mmah_1537 mvk mvk Mmah_1550 Mmah_1550 fni fni queC queC Mmah_1581 Mmah_1581 pyrG pyrG cofC cofC dnaJ dnaJ dnaK dnaK Mmah_1619 Mmah_1619 thiI thiI thrS thrS mat mat hisG hisG mutS2 mutS2 pgk pgk leuS leuS Mmah_1662 Mmah_1662 rfcS rfcS rnfG rnfG dacZ dacZ Mmah_1710 Mmah_1710 Mmah_1716 Mmah_1716 Mmah_1731 Mmah_1731 trpS trpS pheS pheS
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proteins of unknown 3D structure
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tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa)
Mmah_1772Predicted aconitase subunit 1; COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: vap:Vapar_3213 protein of unknown function DUF521; PFAM: protein of unknown function DUF521; SPTR: Q12VZ7 Predicted aconitase subunit 1; PFAM: Protein of unknown function (DUF521). (396 aa)
Mmah_1788COGs: COG0174 Glutamine synthetase; InterPro IPR008146:IPR008147:IPR004809; KEGG: dat:HRM2_45740 GlnA2; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Q8PY99 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (448 aa)
Mmah_1795Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR015140:IPR010624; KEGG: bgl:bglu_2g18700 RAD553; PFAM: KaiA binding; Circadian clock protein KaiC central region; PRIAM: Non-specific serine/threonine protein kinase; SPTR: Q12VV6 KaiC; PFAM: KaiC. (453 aa)
rad50SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (889 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
Mmah_1824COGs: COG0370 Fe2+ transport system protein B; InterProIPR006073:IPR011642:IPR002917:IPR011619:IPR 011640:IPR005225:IPR003373; KEGG: dat:HRM2_10930 FeoB1; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; SPTR: Q8TKD1 Ferrous iron transport protein B; TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; sm [...] (662 aa)
Mmah_1832Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (596 aa)
Mmah_1835Small GTP-binding protein; COGs: COG1163 GTPase; InterPro IPR006073:IPR002917:IPR004095:IPR005225; KEGG: developmentally regulated GTP-binding protein 1; PFAM: GTP-binding protein HSR1-related; TGS domain protein; SPTR: Q12VS9 Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain. (363 aa)
Mmah_1836ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterProIPR005116:IPR003439:IPR013611:IPR003593:IPR 017871; KEGG: atc:AGR_C_3896 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; SPTR: Q12VR9 ABC transporter, ATPase subunit; PFAM: ABC transporter; TOBE domain; TIGRFAM: molybdenum ABC transporter, ATP-binding protein. (365 aa)
Mmah_1856Methyl coenzyme M reductase system, component A2; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR017871:IPR017669; KEGG: ara:Arad_7321 peptide ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12UU2 ABC transporter, fused ATPase subunits; TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2. (535 aa)
Mmah_1866GTP-binding protein; COGs: COG1100 GTPase SAR1 and related small G protein; InterPro IPR000795:IPR001806:IPR002917:IPR005225; KEGG: pmy:Pmen_1476 GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; SPTR: Q12UV1 Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain. (211 aa)
Mmah_1869COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR017552; KEGG: mca:MCA3050 SIS domain-containing protein; PFAM: sugar isomerase (SIS); SPTR: Q12UV4 Hexulose-6-phosphate isomerase; TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase. (200 aa)
Mmah_1871Nucleolar GTP-binding-1 domain protein; COGs: COG1084 GTPase; InterPro IPR006073:IPR002917:IPR010674:IPR001412; KEGG: hypothetical protein; PFAM: Nucleolar GTP-binding-1 domain protein; GTP-binding protein HSR1-related; SPTR: Q8TQZ5 GTP-binding protein; PFAM: Nucleolar GTP-binding protein 1 (NOG1); TIGRFAM: small GTP-binding protein domain. (316 aa)
hisECOGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179; KEGG: gur:Gura_4052 phosphoribosyl-ATP pyrophosphohydrolase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Q12UV8 Phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. (97 aa)
nnrDCarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (488 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (282 aa)
Mmah_1886COGs: COG0370 Fe2+ transport system protein B; InterProIPR006073:IPR011642:IPR013684:IPR002917:IPR 011619:IPR011640:IPR005225:IPR003373; KEGG: ppd:Ppro_3681 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; nucleoside recognition domain protein; Miro domain protein; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; SPTR: Q12UX1 Ferrous iron transport protein B; TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleosid [...] (642 aa)
lysSCOGs: COG1384 Lysyl-tRNA synthetase (class I); InterPro IPR002904:IPR001412; KEGG: noc:Noc_1618 lysine--tRNA ligase; PFAM: Lysyl-tRNA synthetase class 1c; PRIAM: Lysine--tRNA ligase; SPTR: Q12UX8 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa)
Mmah_1903Cobalt ABC transporter, ATPase subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (303 aa)
Mmah_1904ABC transporter related protein; COGs: COG1245 ATPase RNase L inhibitor (RLI) homolog; InterProIPR013283:IPR001450:IPR003439:IPR007209:IPR 003593:IPR017900:IPR017871; KEGG: GSVIVT00001176001; hypothetical protein LOC100249488; K06174 ATP-binding cassette, sub-family E, member 1; PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; SPTR: Q12UY9 ABC transporter, fused ATPase subunits; PFAM: ABC transporter; 4Fe-4S binding domain; Possible metal-binding domain in RNase L inhibitor, RLI. (588 aa)
Mmah_1908Coenzyme F420-0 gamma-glutamyl ligase; COGs: COG1478 conserved hypothetical protein; InterPro IPR002847:IPR008225; KEGG: eba:p2A347 hypothetical protein; PFAM: protein of unknown function DUF129; SPTR: Q12UZ4 Coenzyme F420-0 gamma-glutamyl ligase; TIGRFAM: F420-dependent oxidoreductase; PFAM: F420-0:Gamma-glutamyl ligase; TIGRFAM: F420-0:gamma-glutamyl ligase. (265 aa)
Mmah_1913COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: psa:PST_3318 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Q12V25 Dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. (411 aa)
tiaStRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (425 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (260 aa)
Mmah_1920Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR010624; KEGG: ade:Adeh_3181 putative circadian clock protein, KaiC; PFAM: Circadian clock protein KaiC central region; PRIAM: Non-specific serine/threonine protein kinase; SPTR: Q12V32 Circadian clock protein KaiC; PFAM: KaiC. (455 aa)
Mmah_1939ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593:IPR017871:IPR019825; KEGG: dal:Dalk_3521 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12X01 ABC cobalamin/Fe3+-siderophores transporter, ATPase subunit; PFAM: ABC transporter. (262 aa)
Mmah_1941Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dal:Dalk_5080 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Q12X03 Fe3+-hydroxamate binding protein; PFAM: Periplasmic binding protein. (425 aa)
Mmah_19592-octaprenylphenol hydroxylase; COGs: COG0661 unusual protein kinase; InterPro IPR004147:IPR000719; KEGG: gsu:GSU1088 ubiquinone biosynthesis protein AarF, putative; PFAM: ABC-1 domain protein; SPTR: Q12VH8 2-octaprenylphenol hydroxylase; PFAM: Phosphotransferase enzyme family; ABC1 family. (559 aa)
Mmah_1961ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR017871; KEGG: avn:Avin_18700 ABC transporter, ATP binding component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12VH5 ABC transporter, ATPase subunit; PFAM: ABC transporter. (572 aa)
Mmah_0001ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (411 aa)
argSCOGs: COG0018 Arginyl-tRNA synthetase; InterProIPR015945:IPR005148:IPR008909:IPR001412:IPR 001278; KEGG: dvl:Dvul_1814 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Q12V97 Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (567 aa)
Mmah_0011COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR010624; KEGG: bxe:Bxe_B2609 hypothetical protein; SPTR: Q12V81 ATPase, RecA superfamily; PFAM: KaiC. (245 aa)
Mmah_0012COGs: COG3276 Selenocysteine-specific translation elongation factor; InterPro IPR004161; KEGG: dar:Daro_1810 selenocysteine-specific translation elongation factor SelB; PFAM: elongation factor Tu domain 2 protein; SPTR: Q12V79 Elongation factor Tu, domain 2; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain. (346 aa)
purPIMP biosynthesis enzyme PurP domain protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (355 aa)
Mmah_0047Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR013563:IPR003439:IPR003593:IPR017871:IPR 010066; KEGG: dde:Dde_1182 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Q8TIA3 Oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal [...] (306 aa)
Mmah_0048ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593; KEGG: pin:Ping_0561 ABC transporter for peptide ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q8TIA2 Oligopeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region. (263 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (606 aa)
Mmah_0124DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: gem:GM21_3743 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: Q8TNZ6 Nucleotidyltransferase; PFAM: Nucleotidyltransferase domain. (101 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (234 aa)
Mmah_0134DEAD_2 domain protein; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR010614:IPR006554:IPR006555:IPR014013; KEGG: hypothetical protein; K10844 DNA excision repair protein ERCC-2; PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; SPTR: Q12VQ5 Rad3-related DNA helicases; PFAM: DEAD_2. (733 aa)
Mmah_0135Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (319 aa)
Mmah_0139Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: gem:GM21_3931 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q12VR2 Rhodanese-like protein; PFAM: Rhodanese-like domain. (139 aa)
Mmah_0144InterPro IPR015011; KEGG: sfu:Sfum_0182 hypothetical protein; PFAM: Threonyl-tRNA synthetase editing domain protein; SPTR: A7I9Y6 Putative uncharacterized protein; PFAM: Archaea-specific editing domain of threonyl-tRNA synthetase. (136 aa)
Mmah_0160ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593:IPR017871; KEGG: ppd:Ppro_1463 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12YJ7 ABC Fe3+-siderophore transporter, ATPase subunit; PFAM: ABC transporter. (256 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (367 aa)
Mmah_0189Beta-lactamase domain protein; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: gem:GM21_0314 beta-lactamase domain protein; PFAM: beta-lactamase domain protein; SPTR: Q12UP1 Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily. (248 aa)
Mmah_0190AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959:IPR011704:IPR003593:IPR003960; KEGG: sfu:Sfum_2326 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: Q12UP0 AAA ATPase; PFAM: ATPase family associated with various cellular activities (AAA). (428 aa)
Mmah_0191Hypothetical protein; SPTR: Q46DJ9 Putative uncharacterized protein. (154 aa)
Mmah_0193GTP-binding conserved hypothetical protein TIGR00650; COGs: COG0012 GTPase probable translation factor; InterPro IPR006073:IPR013646:IPR002917:IPR004095; KEGG: hypothetical protein; PFAM: GTPase of unknown function domain protein; GTP-binding protein HSR1-related; TGS domain protein; SPTR: Q12UN7 GTP-binding protein, HSR1-related; PFAM: GTPase of unknown function; TGS domain; GTPase of unknown function C-terminal. (394 aa)
Mmah_0198Thermosome subunit; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterProIPR017998:IPR001844:IPR002423:IPR002194:IPR 012714; KEGG: similar to Chaperonin containing TCP1, subunit 4 (delta); K09496 T-complex protein 1 subunit delta; PFAM: chaperonin Cpn60/TCP-1; SPTR: Q46DJ0 Hsp60; TIGRFAM: thermosome; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal. (539 aa)
Mmah_0200ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: sat:SYN_00209 ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q8TI16 Cobalt import ATP-binding protein cbiO; PFAM: ABC transporter. (274 aa)
Mmah_0201ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: sat:SYN_00209 ABC-type cobalt transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12UN3 ABC transporter, ATPase subunit; PFAM: ABC transporter. (263 aa)
Mmah_0208NADPH-dependent F420 reductase; COGs: COG2085 dinucleotide-binding protein; InterPro IPR004455:IPR010185; KEGG: cps:CPS_4044 NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; SPTR: Q12UM3 Reduced coenzyme F420:NADP oxidoreductase; TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: NADPH-dependent F420 reductase. (245 aa)
Mmah_0216COGs: COG0174 Glutamine synthetase; InterPro IPR008146:IPR008147:IPR004809; KEGG: dat:HRM2_45740 GlnA2; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Q12UM2 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (442 aa)
Mmah_0217PKD domain containing protein; InterPro IPR000601:IPR012859; KEGG: swp:swp_1488 collagenase; PFAM: PKD domain containing protein; Protein of unknown function DUF1628; SMART: PKD domain containing protein; SPTR: C1VHC5 PDK repeat-containing protein; PFAM: Protein of unknown function (DUF1628); PKD domain. (809 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918:IPR000728:IPR004733; KEGG: phosphoribosylformylglycinamidine cyclo-ligase (phosphoribosyl-aminoimidazole synthetase) (AIR synthase); K01933 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Q46E56 Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase rel [...] (332 aa)
Mmah_0225Coenzyme F420-0 gamma-glutamyl ligase; COGs: COG1478 conserved hypothetical protein; InterPro IPR002847:IPR000292:IPR008225; KEGG: eba:p2A347 hypothetical protein; PFAM: protein of unknown function DUF129; SPTR: Q8PX01 F420-0:gamma-glutamyl ligase; TIGRFAM: F420-dependent oxidoreductase; PFAM: F420-0:Gamma-glutamyl ligase; TIGRFAM: F420-0:gamma-glutamyl ligase. (251 aa)
Mmah_0229Replication factor C; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR013748; KEGG: hypothetical protein; K10756 replication factor C subunit 3/5; PFAM: Replication factor C; SPTR: Q12UK9 Replication factor C small subunit; PFAM: ATPase family associated with various cellular activities (AAA); Replication factor C. (343 aa)
Mmah_0232Cobyrinic acid ac-diamide synthase; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: ppd:Ppro_3446 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12UK5 ATPases involved in chromosome partitioning-like protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (247 aa)
guaAAGMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. (191 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (325 aa)
Mmah_0251AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR004201:IPR003959:IPR011704:IPR003338:IPR 003593:IPR003960:IPR005938; KEGG: gur:Gura_2842 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: Q12UG4 AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domai [...] (743 aa)
purCCOGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236; KEGG: maq:Maqu_1689 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Q12UF8 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (243 aa)
purLPhosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (714 aa)
Mmah_0281Protein of unknown function DUF201; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR003806:IPR020561:IPR011761; KEGG: bpr:GBP346_A2048 argininosuccinate lyase 2 (arginosuccinase 2) (asal 2); PFAM: protein of unknown function DUF201; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; SPTR: Q12UB8 Putative uncharacterized protein; PFAM: ATP-grasp domain. (360 aa)
pylSPyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (404 aa)
Mmah_0295AAA ATPase central domain protein; COGs: COG1223 ATPase (AAA+ superfamily); InterPro IPR003959:IPR003593:IPR003960; KEGG: hypothetical protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Q8TLK7 ATPase, AAA family; PFAM: ATPase family associated with various cellular activities (AAA). (367 aa)
panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (429 aa)
Mmah_0316Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR015140:IPR010624; KEGG: ade:Adeh_3181 putative circadian clock protein, KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding; SPTR: Q12UA7 KaiC; PFAM: KaiC. (242 aa)
radBDNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (225 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (294 aa)
Mmah_0324Aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR010067; KEGG: csa:Csal_0183 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein; SPTR: Q8TUK2 Sulfonate ABC transporter, solute-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: NMT1/THI5 like; TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulfonates family. (336 aa)
Mmah_0326ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: sat:SYN_00367 sulfate transport ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12U70 ABC nitrate/sulfonate/bicarbonate transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: nitrate transport ATP-binding subunits C and D. (251 aa)
Mmah_0330ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (277 aa)
Mmah_0332ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (371 aa)
Mmah_0333Putative transcriptional regulator, ModE family; COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847:IPR005116; KEGG: tdn:Suden_1537 ModE family transcriptional regulator; PFAM: regulatory protein LysR; TOBE domain protein; SPTR: Q12U62 Molybdenum-pterin binding domain; PFAM: TOBE domain; Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain. (166 aa)
Mmah_0335Thermosome subunit; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterProIPR017998:IPR001844:IPR002423:IPR002194:IPR 012714; KEGG: hypothetical protein; K09496 T-complex protein 1 subunit delta; PFAM: chaperonin Cpn60/TCP-1; SPTR: Q12U60 Thermosome, Chaperonin Cpn60/TCP-1; TIGRFAM: thermosome; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal. (561 aa)
Mmah_0340COGs: COG4175 ABC-type proline/glycine betaine transport system ATPase component; InterProIPR000644:IPR003439:IPR003593:IPR017871:IPR 005892; KEGG: mxa:MXAN_2249 glycine betaine/L-proline ABC transporter, ATP-binding protein; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Q2KP07 ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. (382 aa)
Mmah_0343COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Q12Z57 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (370 aa)
Mmah_0349Conserved hypothetical protein; COGs: COG0237 Dephospho-CoA kinase; KEGG: hypothetical protein; SPTR: Q8PXA9 UPF0200 protein MM_1313; Belongs to the UPF0200 family. (183 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (865 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (924 aa)
Mmah_0375Hypothetical protein; SPTR: Q46D83 Putative uncharacterized protein. (49 aa)
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (306 aa)
cbiAHydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or amm [...] (438 aa)
Mmah_0394ATP-dependent chaperone ClpB; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270:IPR003959:IPR019489:IPR013093:IPR 011704:IPR004176:IPR003593:IPR018368:IPR017730; KEGG: sfu:Sfum_0263 ATPase; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; SPTR: A3QPW8 ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family ass [...] (869 aa)
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (536 aa)
groSChaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (91 aa)
Mmah_0398ABC transporter related protein; COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR003439:IPR003593; KEGG: scl:sce8517 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q8TJV1 ABC transporter, ATP-binding protein; PFAM: ABC transporter. (264 aa)
rfcLReplication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (489 aa)
Mmah_0411Beta-lactamase domain protein; COGs: COG0426 flavoprotein; InterPro IPR008254:IPR001279; KEGG: dat:HRM2_00830 metallo-beta-lactamase family protein (IMP dehydrogenase/GMP reductase:beta-lactamase-like); PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; SPTR: Q8PS95 Flavodoxin; PFAM: Metallo-beta-lactamase superfamily. (395 aa)
Mmah_0426CbbQ/NirQ/NorQ domain protein; COGs: COG0714 MoxR-like ATPase; InterPro IPR013615:IPR011704; KEGG: neu:NE1919 nitric oxide reductase NorQ protein; PFAM: CbbQ/NirQ/NorQ domain protein; ATPase associated with various cellular activities AAA_5; SPTR: Q8PST8 Conserved protein; PFAM: AAA domain (dynein-related subfamily); CbbQ/NirQ/NorQ C-terminal. (274 aa)
rtcBProtein of unknown function UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: dol:Dole_2571 hypothetical protein; PFAM: protein of unknown function UPF0027; SPTR: Q12U04 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0027; Belongs to the RtcB family. (493 aa)
Mmah_1020Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR014774:IPR010624:IPR020588; KEGG: bbt:BBta_4356 circadian clock protein KaiC; PFAM: Circadian clock protein KaiC central region; SPTR: Q12XJ8 KaiC; PFAM: KaiC. (237 aa)
Mmah_0448COGs: COG0370 Fe2+ transport system protein B; InterProIPR006073:IPR001806:IPR011642:IPR002917:IPR 011619:IPR011640:IPR005225:IPR003373; KEGG: gur:Gura_3001 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; SPTR: O29993 Iron (II) transporter (FeoB-1); TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: [...] (677 aa)
Mmah_0449Proteasome-activating nucleotidase; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterProIPR003959:IPR011704:IPR003593:IPR003960:IPR 005937; KEGG: hypothetical protein; K03066 26S proteasome regulatory subunit T6; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: Q12TR9 26S proteasome subunit P45 family; TIGRFAM: 26S proteasome subunit P45 family; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: 26S proteasome subunit P45 family. (408 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa)
Mmah_0467InterPro IPR008254; KEGG: dal:Dalk_1616 hypothetical protein; SPTR: Q8TTR5 Putative uncharacterized protein; PFAM: Flavodoxin. (165 aa)
eif2gTranslation initiation factor 2 subunit gamma (aeIF-2g); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa)
Mmah_0495Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gur:Gura_2117 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12TT1 Response regulator receiver; PFAM: Response regulator receiver domain. (131 aa)
top6BDNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (617 aa)
top6ADNA topoisomerase (ATP-hydrolyzing); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (367 aa)
Mmah_0508COGs: COG3642 Mn2+-dependent serine/threonine protein kinase; InterPro IPR018934:IPR000719; KEGG: similar to TP53-regulating kinase (p53-related protein kinase) (Nori-2); K08851 TP53 regulating kinase; PFAM: RIO-like kinase; SPTR: Q12WQ8 O-sialoglycoprotein endopeptidase; PFAM: RIO1 family. (189 aa)
Mmah_0515COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR007085:IPR003382:IPR005252; KEGG: gbm:Gbem_1667 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; SPTR: Q466Q5 Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopan [...] (402 aa)
Mmah_0516COGs: COG1829 kinase (sugar kinase superfamily); InterPro IPR006204; PFAM: GHMP kinase; SPTR: Q8PUQ0 Conserved protein; PFAM: GHMP kinases N terminal domain. (291 aa)
Mmah_0519Pantothenate synthetase; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; PFAM: Protein of unknown function DUF137; SPTR: Q12WR9 Pantothenate synthetase; PFAM: Protein of unknown function DUF137. (247 aa)
Mmah_0522COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: dal:Dalk_2506 methionine adenosyltransferase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: Q8CXS7 S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase. (399 aa)
Mmah_0529COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterPro IPR007642:IPR007645:IPR007644; KEGG: NRPB2; NRPB2 (EMBRYO DEFECTIVE 1989); DNA binding; K03010 DNA-directed RNA polymerase II subunit B; PFAM: RNA polymerase beta subunit; RNA polymerase Rpb2 domain 3; RNA polymerase Rpb2 domain 2; SPTR: Q12WS4 DNA-directed RNA polymerase, subunit B'; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; Belongs to the RNA polymerase beta chain family. (545 aa)
Mmah_0530DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (730 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa)
ccatRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (445 aa)
hel308DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (729 aa)
ligDNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (561 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa)
Mmah_0594ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593:IPR017871; KEGG: dol:Dole_1651 ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12X44 ABC cobalamin/Fe3+-siderophores transporter, ATPase subunit; PFAM: ABC transporter. (250 aa)
Mmah_0596Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dal:Dalk_5080 periplasmic binding protein; SPTR: Q12X46 Fe3+-hydroxamate binding protein; PFAM: Periplasmic binding protein. (376 aa)
purDCOGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR020560:IPR020562:IPR020561:IPR011761:IPR 020559:IPR000115; KEGG: sat:SYN_02439 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Q12X37 Phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; [...] (434 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa)
Mmah_0619Adenosinetriphosphatase; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959:IPR011704:IPR003593:IPR003960; KEGG: CDC48; microsomal protein of CDC48 family of ATPases; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: B5IEZ0 AAA family ATPase, CDC48 subfamily; PFAM: ATPase family associated with various cellular activities (AAA). (473 aa)
Mmah_0622COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005482:IPR005479:IPR013651:IPR020561:IPR 005481:IPR011761:IPR011764:IPR004549; KEGG: geo:Geob_3056 acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; RimK domain protein ATP-grasp; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Carbamoyl-phosphate synthetase large chain domain protein; SPTR: Q8PVX7 Pyruvate carboxylase, subunit A; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L [...] (498 aa)
Mmah_0628Replicative DNA helicase Mcm; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterPro IPR008047:IPR001208:IPR011704; KEGG: mcm4; MCM family protein; K02212 minichromosome maintenance protein 4 (cell division control protein 54); PFAM: MCM family protein; ATPase associated with various cellular activities AAA_5; SMART: MCM family protein; SPTR: Q12TE3 Replicative DNA helicase Mcm; PFAM: MCM2/3/5 family; Belongs to the MCM family. (696 aa)
Mmah_0638ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: scl:sce0659 sodium ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12XA3 ABC heme exporter, ATPase subunit; PFAM: ABC transporter. (239 aa)
Mmah_0641NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155:IPR016130; KEGG: dal:Dalk_0980 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: Q12XA6 NADH peroxidase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family. (361 aa)
Mmah_0644Thermosome subunit; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR017998:IPR001844:IPR002423:IPR002194; KEGG: hypothetical protein; K09497 T-complex protein 1 subunit epsilon; PFAM: chaperonin Cpn60/TCP-1; SPTR: Q12XB3 Chaperonin Cpn60/TCP-1; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal. (542 aa)
Mmah_0650Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR008279:IPR002192:IPR000121:IPR018274:IPR 019825:IPR010121; KEGG: gur:Gura_3671 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q12XB9 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding doma [...] (885 aa)
Mmah_0651Hypothetical protein; SPTR: Q8PW30 Putative uncharacterized protein; PFAM: Gar1/Naf1 RNA binding region. (86 aa)
Mmah_0661Hypothetical protein; KEGG: sat:SYN_00497 type I restriction-modification system restriction subunit; SPTR: Q8TK40 Type I site-specific deoxyribonuclease; PFAM: Domain of unknown function (DUF3387). (95 aa)
Mmah_0670RIO-like kinase; COGs: COG1718 Serine/threonine protein kinase involved in cell cycle control; InterProIPR018934:IPR000687:IPR008266:IPR000719:IPR 018935; KEGG: hypothetical protein; K07178 RIO kinase 1; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; SPTR: Q12XD7 Putative uncharacterized protein; PFAM: RIO1 family. (263 aa)
sepSphosphoserine-tRNA(Cys) ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa)
Mmah_0689ERCC4 domain protein; COGs: COG1111 ERCC4-like helicase; InterProIPR006166:IPR000445:IPR011545:IPR001650:IPR 006935:IPR014001:IPR014021; KEGG: hypothetical protein; K10896 fanconi anemia group M protein; PFAM: ERCC4 domain protein; helix-hairpin-helix motif; DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q12XG3 ERCC4-like helicase; PFAM: Helicase conserved C-terminal domain; ERCC4 domain; DEAD/DEAH box helicase. (754 aa)
glySglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (585 aa)
satCOGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650; KEGG: scl:sce0740 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: B5IH63 Sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase; Belongs to the sulfate adenylyltransferase family. (384 aa)
Mmah_0706COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: csa:Csal_0183 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein; SPTR: Q0W479 Predicted ABC-type sulfonate transport system, periplasmic component; PFAM: NMT1/THI5 like. (303 aa)
Mmah_0744DEAD/DEAH box helicase domain protein; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterProIPR001440:IPR001650:IPR018973:IPR011545:IPR 019734:IPR014001:IPR013026:IPR014021; KEGG: dal:Dalk_2442 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; Protein of unknown function DUF1998; helicase domain protein; TPR repeat-containing protein; SMART: DEAD-like helicase; helicase domain protein; Tetratricopeptide repeat; SPTR: Q12YK9 DEAD/DEAH box helicase-like protein; PFAM: Helicase conserve [...] (929 aa)
Mmah_0746DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. (152 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (690 aa)
Mmah_0778COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; SPTR: Q12ZD5 Putative uncharacterized protein. (274 aa)
mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (208 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1056 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (478 aa)
Mmah_0828ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: swd:Swoo_1899 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12Y10 ABC transporter, ATPase subunit; PFAM: ABC transporter. (235 aa)
srp54Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (439 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (443 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (634 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (824 aa)
Mmah_0856Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; COGs: COG3576 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; InterPro IPR011576; KEGG: sat:SYN_02719 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Q12YB7 Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase. (134 aa)
infBTranslation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (593 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (149 aa)
Mmah_0873COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: mfa:Mfla_1656 triphosphoribosyl-dephospho-CoA protein; PFAM: triphosphoribosyl-dephospho-CoA protein; SPTR: Q12ZA3 Triphosphoribosyl-dephospho-CoA protein; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase. (306 aa)
pstBPhosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (255 aa)
Mmah_0883Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterProIPR004504:IPR014774:IPR010624:IPR020588:IPR 010916; KEGG: xca:xccb100_2605 putative RecA/DnaB superfamily regulatory protein; PFAM: Circadian clock protein KaiC central region; SPTR: Q12XV7 KaiC; PFAM: KaiC. (302 aa)
Mmah_0900Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495; KEGG: maq:Maqu_2162 cobalamin synthesis protein, P47K; PFAM: cobalamin synthesis protein P47K; SPTR: Q12V83 Cobalamin synthesis protein, P47K; PFAM: CobW/HypB/UreG, nucleotide-binding domain. (352 aa)
Mmah_0922COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR018209:IPR001697; KEGG: ppd:Ppro_1852 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q8PYY4 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
Mmah_0929ATP dependent helicase, Lhr family; COGs: COG1201 Lhr-like helicase; InterProIPR001650:IPR011545:IPR006935:IPR013701:IPR 014001:IPR014021:IPR002464; KEGG: gbm:Gbem_1577 DEAD/H associated domain protein; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q12XX9 DEAD/DEAH box helicase-like protein; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. (941 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (263 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (633 aa)
carACOGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006220:IPR011702:IPR001317:IPR002474:IPR 000991:IPR006274; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Q12XK5 Carbamoyl-phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (365 aa)
carBCOGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483:IPR003135:IPR005479:IPR003806:IPR 013651:IPR011607:IPR005480:IPR005481:IPR011761:IPR006275; KEGG: gur:Gura_1864 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; SPTR: Q12XK4 C [...] (1079 aa)
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: hypothetical protein; K01940 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Q12XK3 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (394 aa)
Mmah_0966ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703:IPR011704:IPR000215; KEGG: scl:sce5905 methanol dehydrogenase regulator (MoxR)-like protein; PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SPTR: Q12XR6 ATPase associated with various cellular activities, AAA_3; PFAM: ATPase family associated with various cellular activities (AAA). (322 aa)
Mmah_0972Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR003495; KEGG: bja:bll7768 hypothetical protein; PFAM: cobalamin synthesis protein P47K; SPTR: Q8PXZ4 Conserved protein; PFAM: CobW/HypB/UreG, nucleotide-binding domain. (373 aa)
Mmah_0985COGs: COG0703 Shikimate kinase; InterPro IPR000767:IPR000623; KEGG: gbm:Gbem_0200 shikimate kinase; PFAM: shikimate kinase; SPTR: Q466X5 Shikimate kinase; PFAM: Shikimate kinase. (172 aa)
Mmah_0997Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (802 aa)
Mmah_0999Conserved hypothetical protein; InterPro IPR011761:IPR005479; KEGG: sfr:Sfri_3838 hypothetical protein; SPTR: A3KIM7 Putative uncharacterized protein; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain. (426 aa)
Mmah_1000Iron-regulated ABC transporter ATPase subunit SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003439:IPR003593; KEGG: dat:HRM2_29340 SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q8THV5 ABC transporter, ATP-binding protein; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC. (247 aa)
Mmah_1002BRAMP domain protein; COGs: COG0655 Multimeric flavodoxin WrbA; KEGG: cbd:CBUD_0810 BRAMP; SPTR: Q46AT4 BRAMP; PFAM: NADPH-dependent FMN reductase. (225 aa)
Mmah_1006Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001802:IPR001756:IPR006121:IPR 008250:IPR005834:IPR018303:IPR017969:IPR000150:IPR006122:I PR006403:IPR006416; KEGG: oan:Oant_0287 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Q8TR42 P-type copper-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily [...] (909 aa)
Mmah_1009COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459:IPR000873; KEGG: pca:Pcar_1242 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q12Y97 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (490 aa)
Mmah_1019Peptidase S16, Lon-like protease; COGs: COG1067 ATP-dependent protease; InterProIPR001984:IPR008269:IPR000523:IPR003593:IPR 004663; KEGG: dal:Dalk_1252 AAA ATPase; PFAM: peptidase S16 lon domain protein; magnesium chelatase ChlI subunit; PRIAM: Endopeptidase La; SMART: AAA ATPase; SPTR: Q12XJ7 Peptidase S16, lon like protease; TIGRFAM: peptidase S16, Lon-like protease; PFAM: Magnesium chelatase, subunit ChlI; Sigma-54 interaction domain; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; Belongs to the peptidase S16 family. (626 aa)
aroKCOGs: COG1685 shikimate kinase; InterPro IPR013750:IPR006204:IPR010189; KEGG: HSK; HSK (HOMOSERINE KINASE); homoserine kinase; K00872 homoserine kinase; PFAM: GHMP kinase; GHMP kinase domain protein; PRIAM: Shikimate kinase; SPTR: Q12XK2 Shikimate kinase; TIGRFAM: shikimate kinase; PFAM: GHMP kinases N terminal domain; TIGRFAM: shikimate kinase. (285 aa)
Mmah_1045COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR007409:IPR006935:IPR014001:IPR014021:IPR 004473; KEGG: dde:Dde_3424 HsdR family type I site-specific deoxyribonuclease; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: A3X0U8 Restriction enzyme type I helicase subunits and related helicase; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res [...] (965 aa)
Mmah_1050UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR014016:IPR014017; KEGG: nme:NMB1447 ATP-dependent DNA helicase; PFAM: UvrD/REP helicase; SPTR: A6UNC7 UvrD/REP helicase; PFAM: Protein of unknown function (DUF2800); UvrD/REP helicase. (1018 aa)
Mmah_1073Beta-lactamase domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001279:IPR001763; KEGG: sat:SYN_01287 hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q8TNG7 Metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain. (456 aa)
cysSCOGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015413:IPR015273:IPR002308; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); PRIAM: Cysteine--tRNA ligase; SPTR: Q9UWP1 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase. (471 aa)
rtcARNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (351 aa)
Mmah_1077AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR004201:IPR003959:IPR011704:IPR003338:IPR 003593:IPR003960:IPR005938; KEGG: rlg:Rleg_7058 AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: Q8Q089 Cell division cycle protein; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: ATPase family associated with various cellular activities (AAA); [...] (761 aa)
Mmah_1087KEGG: dal:Dalk_1616 hypothetical protein; PFAM: Flavodoxin. (170 aa)
lig-2DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (569 aa)
rimKCOGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR003806:IPR013651:IPR011761:IPR004666; KEGG: avn:Avin_05140 ribosomal protein S6 modification enzyme RimK; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; SPTR: Q12Y24 Ribosomal protein S6 modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family. (301 aa)
Mmah_1100DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR001650:IPR011545:IPR014001:IPR014021:IPR 000629:IPR014014; KEGG: dvm:DvMF_2125 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: B8GGY3 DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (431 aa)
ribLGlycerol-3-phosphate cytidylyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (142 aa)
Mmah_1130COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: dvm:DvMF_2677 response regulator receiver sensor hybrid histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q8PSW9 Transcriptional regulator; PFAM: Response regulator receiver domain. (140 aa)
Mmah_1150Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gur:Gura_2117 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12XN2 Response regulator receiver; PFAM: Response regulator receiver domain. (129 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
Mmah_1169Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: dat:HRM2_16760 AcsF; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12XL4 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (251 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
gatAaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (473 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (93 aa)
tmkCOGs: COG0125 Thymidylate kinase; InterPro IPR000062:IPR018094; KEGG: mmb:Mmol_1138 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Q12VF9 Probable thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. (199 aa)
cetZTubulin/FtsZ GTPase; Involved in cell shape control; Belongs to the CetZ family. (368 aa)
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (226 aa)
Mmah_2000DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: gur:Gura_0409 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: A7I6V0 DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain. (99 aa)
Mmah_2008Putative circadian clock protein, KaiC; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR004504:IPR014774:IPR015140:IPR010624; KEGG: bbt:BBta_4356 circadian clock protein KaiC; PFAM: Circadian clock protein KaiC central region; KaiA binding; PRIAM: Non-specific serine/threonine protein kinase; SPTR: Q12VE1 KaiC; PFAM: KaiC. (257 aa)
Mmah_2009ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR000695:IPR001757:IPR006068:IPR008250:IPR 005834:IPR004014:IPR018303; KEGG: gbm:Gbem_2237 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Q12VE0 Cation transporter, P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transp [...] (889 aa)
Mmah_2012Cobalt ABC transporter, ATPase subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (435 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (597 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (881 aa)
Mmah_2020ABC-2 type transporter; InterPro IPR013526:IPR013525:IPR000412; KEGG: sat:SYN_00773 ABC transporter permease protein; PFAM: ABC-2 type transporter; SPTR: Q12VB8 ABC transporter, inner membrane subunit; PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family. (261 aa)
Mmah_2021ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: sat:SYN_00774 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12VB7 ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: ATP-binding ABC transporter family nodulation protein NodI. (285 aa)
Mmah_2026Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001756:IPR008250:IPR005834:IPR 018303:IPR006416:IPR006403; KEGG: bba:Bd2297 heavy-metal transporting CPx-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: O30085 Probable copper-exporting P-type ATPase B; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or si [...] (658 aa)
Mmah_1181Protein of unknown function DUF201; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase; InterPro IPR003806:IPR013651:IPR011761; KEGG: vap:Vapar_3083 protein of unknown function DUF201; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; SPTR: Q8TJB8 Putative uncharacterized protein; PFAM: ATP-grasp domain. (379 aa)
Mmah_1188ABC transporter related protein; COGs: COG1124 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: dat:HRM2_40420 ABC-type transport system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q46GE0 ABC transporter, ATP-binding protein; PFAM: ABC transporter. (210 aa)
mobAFormate dehydrogenase family accessory protein FdhD; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (219 aa)
Mmah_1199COGs: COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain; InterPro IPR015285:IPR018934:IPR000687:IPR008266; KEGG: hypothetical protein; K07179 RIO kinase 2; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1; SPTR: Q8PSJ8 Serine/threonine protein kinase; PFAM: RIO1 family; Rio2, N-terminal. (301 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (351 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
Mmah_1224COGs: COG0514 Superfamily II DNA helicase; InterProIPR002121:IPR001650:IPR011545:IPR018982:IPR 014001:IPR014021:IPR018329:IPR006293; KEGG: sat:SYN_02584 superfamily II DNA helicase; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein; SPTR: Q12ZP3 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP [...] (599 aa)
guaABGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (304 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
ftsZ-2Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (386 aa)
Mmah_1260Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: sat:SYN_01224 metallo cofactor biosynthesis protein; PFAM: Radical SAM domain protein; SPTR: Q8PU73 Metallo cofactor biosynthesis protein; PFAM: Radical SAM superfamily. (199 aa)
engBGTP-binding protein HSR1-related protein; Necessary for normal cell division and for the maintenance of normal septation. (207 aa)
Mmah_1278AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (489 aa)
pheTCOGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR005146:IPR005147:IPR004531; KEGG: phenylalanyl-tRNA synthetase beta chain (EC:6.1.1.20); K01890 phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetase B5; B3/4 domain protein; PRIAM: Phenylalanine--tRNA ligase; SPTR: Q12YP2 Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (539 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (230 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (83 aa)
Mmah_1337ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR000695:IPR001757:IPR006068:IPR008250:IPR 005834:IPR004014:IPR018303; KEGG: dal:Dalk_2925 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Q12XJ2 Cation transporting P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transp [...] (885 aa)
cmkCOGs: COG1102 Cytidylate kinase; InterPro IPR011892; KEGG: wbm:Wbm0321 adenylate kinase; PRIAM: Cytidylate kinase; SPTR: Q12ZS5 Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase, putative. (179 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
Mmah_1385Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: sfu:Sfum_4099 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12X77 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. (255 aa)
Mmah_1391ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: sfu:Sfum_2734 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12X71 ABC transporter, ATPase subunit; PFAM: ABC transporter. (255 aa)
Mmah_1392ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: sfu:Sfum_2735 ABC-3 protein; PFAM: ABC-3 protein; SPTR: Q46DS8 Zinc ABC transporter, permease protein; PFAM: ABC 3 transport family. (270 aa)
gatDglutamyl-tRNA(Gln) amidotransferase, subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (414 aa)
Mmah_1404IMP biosynthesis enzyme PurP domain protein; COGs: COG1759 ATP-utilizing protein of ATP-grasp superfamily (probably carboligase); InterPro IPR010672:IPR009720; PFAM: IMP biosynthesis enzyme PurP domain protein; IMP biosynthesis enzyme PurP; SPTR: Q12X62 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1297); Protein of unknown function (DUF1246). (385 aa)
Mmah_1411Mur ligase middle domain protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR013221; KEGG: azo:azo0882 UDP-N-acetylmuramoylalanine-D-glutamate ligase; PFAM: Mur ligase middle domain protein; SPTR: Q12X55 Putative uncharacterized protein; PFAM: Mur ligase middle domain. (444 aa)
Mmah_1412Methanogenesis marker 13 metalloprotein; COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR017675; KEGG: geo:Geob_2466 nitrogenase; SPTR: Q8PZH8 Conserved protein; TIGRFAM: methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: putative methanogenesis marker 13 metalloprotein. (369 aa)
Mmah_1413Mo-nitrogenase iron protein subunit NifH; COGs: COG1348 Nitrogenase subunit NifH (ATPase); InterPro IPR000392; KEGG: sfu:Sfum_1019 nitrogenase reductase; PFAM: NifH/frxC-family protein; PRIAM: Nitrogenase; SPTR: Q12X53 Nitrogenase iron protein subunit NifH; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein. (265 aa)
cbiA-2Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or amm [...] (481 aa)
hflXGTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (428 aa)
Mmah_1424Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: geo:Geob_0482 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Q8PVQ8 Putative uncharacterized protein; PFAM: Rhodanese-like domain. (89 aa)
atpDV-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (205 aa)
atpBATP synthase, B subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa)
atpAATP synthase, A subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (576 aa)
atpFVacuolar H+transporting two-sector ATPase F subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (100 aa)
atpCATP synthase A1, C subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (357 aa)
atpEH+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (183 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (570 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (502 aa)
Mmah_1479COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR017998:IPR001844:IPR002423:IPR002194; KEGG: hypothetical protein; K09493 T-complex protein 1 subunit alpha; PFAM: chaperonin Cpn60/TCP-1; SPTR: Q8TSE1 Hsp60; PFAM: TCP-1/cpn60 chaperonin family. (536 aa)
hisSCOGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR002314:IPR004154:IPR006195:IPR015807; KEGG: sat:SYN_02534 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Q12TM4 Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; ATP phosphoribosyltransferase, regulatory subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa)
Mmah_1509Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (179 aa)
Mmah_1511COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004820:IPR004821:IPR006418; KEGG: vei:Veis_4845 cytidyltransferase-like protein; PFAM: cytidylyltransferase; PRIAM: Nicotinamide-nucleotide adenylyltransferase; SPTR: Q12TK4 Nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain. (173 aa)
Mmah_1537Beta-lactamase domain protein; COGs: COG0426 flavoprotein; InterPro IPR008254:IPR001279:IPR001226; KEGG: sfu:Sfum_3253 flavodoxin/nitric oxide synthase; PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; SPTR: Q12TJ2 Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin. (400 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (305 aa)
Mmah_1550Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (259 aa)
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (363 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (228 aa)
Mmah_1581COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR003806:IPR013651:IPR011761:IPR004666; KEGG: afw:Anae109_2113 alpha-L-glutamate ligase; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201; SPTR: Q8Q0M5 Tetrahydromethanopterin:alpha-L-glutamate ligase; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family. (301 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (529 aa)
cofCPhospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (214 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (398 aa)
dnaKChaperone protein DnaK; Acts as a chaperone. (623 aa)
Mmah_1619Protein of unknown function DUF201; COGs: COG1821 ATP-utilizing protein (ATP-grasp superfamily); InterPro IPR003806:IPR011761; KEGG: bxe:Bxe_B2459 hypothetical protein; PFAM: protein of unknown function DUF201; SPTR: Q12WE3 Putative uncharacterized protein; PFAM: ATP-grasp domain. (307 aa)
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (391 aa)
thrSSer-tRNA(Thr) hydrolase; COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158:IPR002314:IPR004154:IPR015011:IPR 006195:IPR002320; KEGG: dma:DMR_10590 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; Anticodon-binding domain protein; tRNA synthetase class II (G H P and S); SPTR: Q12WD4 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); Archaea-specific editing domain of threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II [...] (631 aa)
matMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (399 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (284 aa)
mutS2DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (700 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: ppd:Ppro_1694 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Q12WB3 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (413 aa)
leuSCOGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015413:IPR002300:IPR013155:IPR001412:IPR 004493; KEGG: leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); SPTR: Q12WA2 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, archaeal and cytosolic family. (961 aa)
Mmah_1662ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: gur:Gura_2760 cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: O27739 Putative cobalt import ATP-binding protein cbiO; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit. (305 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (318 aa)
rnfGElectron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (183 aa)
dacZProtein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (289 aa)
Mmah_1710COGs: COG3593 ATP-dependent endonuclease of the OLD family; KEGG: sml:Smlt2491 hypothetical protein; SPTR: Q468T4 Putative uncharacterized protein. (584 aa)
Mmah_1716ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: mxa:MXAN_4199 putative macrolide efflux ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Q12ZM4 ABC transporter, ATPase subunit; PFAM: ABC transporter. (228 aa)
Mmah_1731Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR008284; KEGG: mxa:MXAN_2759 molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; SPTR: Q12W44 Molybdopterin binding protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (178 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (432 aa)
pheSCOGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR002319:IPR006195:IPR004529; KEGG: similar to predicted protein; K01889 phenylalanyl-tRNA synthetase alpha chain; PFAM: phenylalanyl-tRNA synthetase class IIc; PRIAM: Phenylalanine--tRNA ligase; SPTR: Q12W38 Phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit. (491 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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