STRINGSTRING
pyrE pyrE Mmah_1922 Mmah_1922 Mmah_0845 Mmah_0845 Mmah_1094 Mmah_1094 hpt hpt prs prs purF purF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (180 aa)
Mmah_1922COGs: COG0856 Orotate phosphoribosyltransferase homologs; InterPro IPR000836:IPR002375; KEGG: GG14926 gene product from transcript GG14926-RA; PFAM: phosphoribosyltransferase; SPTR: Q12V34 PyrE-like protein; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (203 aa)
Mmah_0845COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: sat:SYN_03353 xanthine-guanine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Q8THD6 Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. (232 aa)
Mmah_1094COGs: COG1926 phosphoribosyltransferase; InterPro IPR000836; KEGG: vap:Vapar_1971 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: Q46CA8 Putative uncharacterized protein; PFAM: Phosphoribosyl transferase domain. (220 aa)
hptPhosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (190 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (282 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (470 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
Server load: low (14%) [HD]