node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmah_1922 | prs | Mmah_1922 | Mmah_1881 | COGs: COG0856 Orotate phosphoribosyltransferase homologs; InterPro IPR000836:IPR002375; KEGG: GG14926 gene product from transcript GG14926-RA; PFAM: phosphoribosyltransferase; SPTR: Q12V34 PyrE-like protein; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.821 |
Mmah_1922 | pyrE | Mmah_1922 | Mmah_0605 | COGs: COG0856 Orotate phosphoribosyltransferase homologs; InterPro IPR000836:IPR002375; KEGG: GG14926 gene product from transcript GG14926-RA; PFAM: phosphoribosyltransferase; SPTR: Q12V34 PyrE-like protein; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.913 |
hpt | prs | Mmah_1740 | Mmah_1881 | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.662 |
hpt | purF | Mmah_1740 | Mmah_0361 | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.685 |
hpt | pyrE | Mmah_1740 | Mmah_0605 | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.616 |
prs | Mmah_1922 | Mmah_1881 | Mmah_1922 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | COGs: COG0856 Orotate phosphoribosyltransferase homologs; InterPro IPR000836:IPR002375; KEGG: GG14926 gene product from transcript GG14926-RA; PFAM: phosphoribosyltransferase; SPTR: Q12V34 PyrE-like protein; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.821 |
prs | hpt | Mmah_1881 | Mmah_1740 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.662 |
prs | purF | Mmah_1881 | Mmah_0361 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.956 |
prs | pyrE | Mmah_1881 | Mmah_0605 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.904 |
purF | hpt | Mmah_0361 | Mmah_1740 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.685 |
purF | prs | Mmah_0361 | Mmah_1881 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.956 |
purF | pyrE | Mmah_0361 | Mmah_0605 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.746 |
pyrE | Mmah_1922 | Mmah_0605 | Mmah_1922 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | COGs: COG0856 Orotate phosphoribosyltransferase homologs; InterPro IPR000836:IPR002375; KEGG: GG14926 gene product from transcript GG14926-RA; PFAM: phosphoribosyltransferase; SPTR: Q12V34 PyrE-like protein; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.913 |
pyrE | hpt | Mmah_0605 | Mmah_1740 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.616 |
pyrE | prs | Mmah_0605 | Mmah_1881 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). | 0.904 |
pyrE | purF | Mmah_0605 | Mmah_0361 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.746 |