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guaAA guaAA cbiA cbiA Mmah_0472 Mmah_0472 pdxT pdxT carA carA Mmah_0963 Mmah_0963 Mmah_0964 Mmah_0964 Mmah_1247 Mmah_1247 purQ purQ cbiA-2 cbiA-2 cobQ cobQ Mmah_1508 Mmah_1508 pyrG pyrG hisH hisH
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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guaAAGMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP. (191 aa)
cbiAHydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or amm [...] (438 aa)
Mmah_0472PfpI peptidase; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818:IPR006286; KEGG: gme:Gmet_2409 peptidase C56, PfpI; PFAM: ThiJ/PfpI domain protein; SPTR: Q8TMW8 Intracellular protease I; TIGRFAM: intracellular protease, PfpI family; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family. (167 aa)
pdxTPyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (199 aa)
carACOGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006220:IPR011702:IPR001317:IPR002474:IPR 000991:IPR006274; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Q12XK5 Carbamoyl-phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (365 aa)
Mmah_0963Von Willebrand factor type A; InterPro IPR002035:IPR020003; KEGG: scl:sce5902 hypothetical protein; SMART: von Willebrand factor type A; SPTR: Q12XR9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1355). (811 aa)
Mmah_0964InterPro IPR011933; KEGG: scl:sce5903 hypothetical protein; SPTR: Q12XR8 Conserved hypothetical membrane protein; TIGRFAM: conserved hypothetical protein; PFAM: Aerotolerance regulator N-terminal; TIGRFAM: N-terminal double-transmembrane domain. (624 aa)
Mmah_1247ThiJ/PfpI domain protein; COGs: COG0693 Putative intracellular protease/amidase; InterPro IPR002818; KEGG: geo:Geob_2352 intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; SPTR: Q12ZS1 ThiJ/PfpI; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family. (175 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (230 aa)
cbiA-2Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or amm [...] (481 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (490 aa)
Mmah_1508COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006220:IPR011702:IPR001317:IPR000991:IPR 006221; KEGG: ASB1; anthranilate synthase beta subunit; K01658 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: Q465F0 Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (194 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (529 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (202 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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