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Mmah_0596 Mmah_0596 Mmah_0012 Mmah_0012 Mmah_0019 Mmah_0019 Mmah_0022 Mmah_0022 Mmah_0044 Mmah_0044 Mmah_0054 Mmah_0054 Mmah_0063 Mmah_0063 Mmah_0110 Mmah_0110 Mmah_0111 Mmah_0111 Mmah_0134 Mmah_0134 flpA flpA metG metG Mmah_0188 Mmah_0188 Mmah_0191 Mmah_0191 Mmah_0208 Mmah_0208 Mmah_0222 Mmah_0222 Mmah_0229 Mmah_0229 Mmah_0285 Mmah_0285 Mmah_0290 Mmah_0290 Mmah_0301 Mmah_0301 pan pan Mmah_0343 Mmah_0343 dbh dbh Mmah_0359 Mmah_0359 Mmah_0364 Mmah_0364 alaS alaS Mmah_0376 Mmah_0376 moaA moaA iscS iscS Mmah_0394 Mmah_0394 Mmah_0432 Mmah_0432 Mmah_0448 Mmah_0448 uvrB uvrB Mmah_0483 Mmah_0483 rps24e rps24e Mmah_0496 Mmah_0496 Mmah_0498 Mmah_0498 Mmah_0514 Mmah_0514 Mmah_0531 Mmah_0531 Mmah_0543 Mmah_0543 Mmah_0568 Mmah_0568 Mmah_0571 Mmah_0571 Mmah_0572 Mmah_0572 Mmah_0573 Mmah_0573 Mmah_0593 Mmah_0593 Mmah_0609 Mmah_0609 Mmah_0625 Mmah_0625 Mmah_0626 Mmah_0626 Mmah_0647 Mmah_0647 Mmah_0650 Mmah_0650 Mmah_0670 Mmah_0670 tgtA tgtA Mmah_0677 Mmah_0677 Mmah_0681 Mmah_0681 Mmah_0689 Mmah_0689 glyS glyS Mmah_0701 Mmah_0701 pfdB pfdB Mmah_0747 Mmah_0747 Mmah_0761 Mmah_0761 Mmah_0777 Mmah_0777 ileS ileS Mmah_0788 Mmah_0788 psmA psmA rrp4 rrp4 Mmah_0813 Mmah_0813 Mmah_0821 Mmah_0821 Mmah_0831 Mmah_0831 gyrB gyrB gyrA gyrA Mmah_0875 Mmah_0875 Mmah_0891 Mmah_0891 Mmah_0904 Mmah_0904 Mmah_0908 Mmah_0908 Mmah_0911 Mmah_0911 Mmah_0912 Mmah_0912 Mmah_0924 Mmah_0924 Mmah_0931 Mmah_0931 Mmah_0967 Mmah_0967 Mmah_0974 Mmah_0974 Mmah_0976 Mmah_0976 Mmah_0996 Mmah_0996 Mmah_1023 Mmah_1023 Mmah_1042 Mmah_1042 Mmah_1044 Mmah_1044 Mmah_1063 Mmah_1063 Mmah_1068 Mmah_1068 Mmah_1079 Mmah_1079 Mmah_1084 Mmah_1084 Mmah_1100 Mmah_1100 Mmah_1143 Mmah_1143 Mmah_1146 Mmah_1146 Mmah_1151 Mmah_1151 cdhC cdhC Mmah_1175 Mmah_1175 tfe tfe topA topA Mmah_1198 Mmah_1198 pfdA pfdA Mmah_1250 Mmah_1250 Mmah_1282 Mmah_1282 Mmah_1284 Mmah_1284 Mmah_1286 Mmah_1286 Mmah_1291 Mmah_1291 Mmah_1297 Mmah_1297 Mmah_1299 Mmah_1299 Mmah_1301 Mmah_1301 Mmah_1311 Mmah_1311 cas1 cas1 Mmah_1314 Mmah_1314 Mmah_1318 Mmah_1318 Mmah_1328 Mmah_1328 Mmah_1333 Mmah_1333 Mmah_1335 Mmah_1335 Mmah_1341 Mmah_1341 Mmah_1367 Mmah_1367 Mmah_1377 Mmah_1377 Mmah_1394 Mmah_1394 argH argH Mmah_1416 Mmah_1416 atpD atpD atpE atpE Mmah_1449 Mmah_1449 Mmah_1479 Mmah_1479 Mmah_1503 Mmah_1503 corA corA Mmah_1520 Mmah_1520 cofH-2 cofH-2 dnaK dnaK Mmah_1633 Mmah_1633 leuS leuS Mmah_1666 Mmah_1666 Mmah_1676 Mmah_1676 Mmah_1701 Mmah_1701 Mmah_1708 Mmah_1708 eif2b eif2b uvrC uvrC mtrG mtrG Mmah_1794 Mmah_1794 Mmah_1796 Mmah_1796 rad50 rad50 Mmah_1809 Mmah_1809 smc smc Mmah_1811 Mmah_1811 Mmah_1834 Mmah_1834 Mmah_1835 Mmah_1835 Mmah_1852 Mmah_1852 Mmah_1879 Mmah_1879 Mmah_1899 Mmah_1899 glyA glyA Mmah_1930 Mmah_1930 nac nac Mmah_1943 Mmah_1943 Mmah_1948 Mmah_1948 Mmah_1973 Mmah_1973 Mmah_1978 Mmah_1978 lolD lolD Mmah_1995 Mmah_1995 Mmah_1998 Mmah_1998
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proteins of unknown 3D structure
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Mmah_0596Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dal:Dalk_5080 periplasmic binding protein; SPTR: Q12X46 Fe3+-hydroxamate binding protein; PFAM: Periplasmic binding protein. (376 aa)
Mmah_0012COGs: COG3276 Selenocysteine-specific translation elongation factor; InterPro IPR004161; KEGG: dar:Daro_1810 selenocysteine-specific translation elongation factor SelB; PFAM: elongation factor Tu domain 2 protein; SPTR: Q12V79 Elongation factor Tu, domain 2; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain. (346 aa)
Mmah_0019Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XC6 ATP-binding region, ATPase-like protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (470 aa)
Mmah_0022Nucleic acid binding OB-fold tRNA/helicase-type; COGs: COG1599 Single-stranded DNA-binding replication protein A (RPA) large (70 kD) subunit and related ssDNA-binding protein; InterPro IPR004365; KEGG: hypothetical protein; K07466 replication factor A1; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Q12V72 Single-stranded DNA-binding replication protein A (RPA) large (70 kD) subunit and related ssDNA-binding proteins; PFAM: OB-fold nucleic acid binding domain. (374 aa)
Mmah_0044Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216:IPR004033:IPR013217; KEGG: sme:SM_b20059 SAM-dependent methyltransferase; PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; SPTR: Q8TIA7 Phosphatidylethanolamine N-methyltransferase; PFAM: Methyltransferase domain. (258 aa)
Mmah_0054COGs: COG1109 Phosphomannomutase; InterProIPR005841:IPR005844:IPR005846:IPR005843:IPR 005845:IPR016066; KEGG: cla:Cla_1567 phosphoglucomutase/phosphomannomutase family protein; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; PRIAM: Phosphoglucosamine mutase; SPTR: Q46AY7 Probable phosphoglucosamine mutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomuta [...] (431 aa)
Mmah_0063Transposase, IS605 OrfB family; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095:IPR001959; KEGG: dno:DNO_0387 IS605 family transposase; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; SPTR: Q466U3 Transposase; TIGRFAM: transposase, IS605 OrfB family; PFAM: Helix-turn-helix domain; Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region. (379 aa)
Mmah_0110COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR003661:IPR 001610:IPR000014:IPR000700:IPR005467; KEGG: dat:HRM2_p00340 predicted sensory/regulatory protein RpfC; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12ZM3 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kina [...] (599 aa)
Mmah_0111Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR013656:IPR001610:IPR 000014:IPR000700; KEGG: lch:Lcho_2590 multi-sensor hybrid histidine kinase; PFAM: PAS fold-4 domain protein; PAS fold domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (270 aa)
Mmah_0134DEAD_2 domain protein; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR010614:IPR006554:IPR006555:IPR014013; KEGG: hypothetical protein; K10844 DNA excision repair protein ERCC-2; PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; SPTR: Q12VQ5 Rad3-related DNA helicases; PFAM: DEAD_2. (733 aa)
flpArRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa)
Mmah_0188Hypothetical protein; SPTR: Q12UP2 Putative uncharacterized protein. (304 aa)
Mmah_0191Hypothetical protein; SPTR: Q46DJ9 Putative uncharacterized protein. (154 aa)
Mmah_0208NADPH-dependent F420 reductase; COGs: COG2085 dinucleotide-binding protein; InterPro IPR004455:IPR010185; KEGG: cps:CPS_4044 NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; SPTR: Q12UM3 Reduced coenzyme F420:NADP oxidoreductase; TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: NADPH-dependent F420 reductase. (245 aa)
Mmah_0222KEGG: hypothetical protein similar to erythrocyte membrane-associated giant protein antigen 332; SPTR: Q12UL6 Putative uncharacterized protein. (390 aa)
Mmah_0229Replication factor C; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR013748; KEGG: hypothetical protein; K10756 replication factor C subunit 3/5; PFAM: Replication factor C; SPTR: Q12UK9 Replication factor C small subunit; PFAM: ATPase family associated with various cellular activities (AAA); Replication factor C. (343 aa)
Mmah_0285COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013656:IPR013767:IPR 003594:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: dal:Dalk_4458 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TKN3 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: [...] (625 aa)
Mmah_0290Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: ppd:Ppro_2189 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: Q12UA3 Aminotransferase; PFAM: Aminotransferase class I and II. (363 aa)
Mmah_0301Transcriptional regulator, XRE family; COGs: COG1813 transcription factor homolog of eukaryotic MBF1; InterPro IPR001387:IPR004451; KEGG: hypothetical protein; K03627 putative transcription factor; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Q12U90 Transcriptional regulator, XRE family; PFAM: Helix-turn-helix; TIGRFAM: conserved hypothetical protein TIGR00270. (160 aa)
panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (429 aa)
Mmah_0343COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Q12Z57 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (370 aa)
dbhDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (363 aa)
Mmah_03595-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR003692:IPR008040:IPR002821; KEGG: noc:Noc_0378 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; Hydantoinase/oxoprolinase; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: Q8TNI5 5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. (1202 aa)
Mmah_0364COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: pin:Ping_1734 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: Q8PV83 Putative transport channel protein; PFAM: Mechanosensitive ion channel. (418 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (924 aa)
Mmah_0376KEGG: viral A-type inclusion protein; SPTR: Q64B45 Putative uncharacterized protein. (429 aa)
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (306 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (397 aa)
Mmah_0394ATP-dependent chaperone ClpB; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270:IPR003959:IPR019489:IPR013093:IPR 011704:IPR004176:IPR003593:IPR018368:IPR017730; KEGG: sfu:Sfum_0263 ATPase; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; SPTR: A3QPW8 ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family ass [...] (869 aa)
Mmah_0432COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013656:IPR013767:IPR 003594:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: pla:Plav_0648 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8PTE2 Sensor protein; TIGRFAM: PAS sensor [...] (1034 aa)
Mmah_0448COGs: COG0370 Fe2+ transport system protein B; InterProIPR006073:IPR001806:IPR011642:IPR002917:IPR 011619:IPR011640:IPR005225:IPR003373; KEGG: gur:Gura_3001 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; SPTR: O29993 Iron (II) transporter (FeoB-1); TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: [...] (677 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa)
Mmah_0483L-lysine 2,3-aminomutase; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: dat:HRM2_29300 YodO; PFAM: Radical SAM domain protein; PRIAM: Lysine 2,3-aminomutase; SPTR: Q46EP3 L-lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Lysine-2,3-aminomutase; TIGRFAM: KamA family protein. (358 aa)
rps24eCOGs: COG2004 Ribosomal protein S24E; InterPro IPR001976; KEGG: similar to ribosomal protein S24e; K02974 small subunit ribosomal protein S24e; PFAM: Ribosomal protein S24e; SPTR: Q12TT3 30S ribosomal protein S24e; PFAM: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (102 aa)
Mmah_0496COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold. (755 aa)
Mmah_0498Dimethylamine corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: geo:Geob_2541 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Q12W94 Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. (203 aa)
Mmah_0514Hypothetical protein; SPTR: Q12WR4 Putative uncharacterized protein. (187 aa)
Mmah_0531DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (886 aa)
Mmah_0543Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: Q12XI7 Pyruvate flavodoxin/ferredoxin oxidoreductase-like protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase. (576 aa)
Mmah_0568COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106; KEGG: pfl:PFL_3809 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: Q12X09 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase. (332 aa)
Mmah_0571KEGG: variable membrane protein precursor; SPTR: Q12X12 Putative uncharacterized protein. (580 aa)
Mmah_0572Hypothetical protein; SPTR: Q12X13 Putative uncharacterized protein. (87 aa)
Mmah_0573InterPro IPR008611; KEGG: hypothetical protein; SPTR: Q4DSZ8 Putative uncharacterized protein. (318 aa)
Mmah_0593COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013656:IPR013767:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: glo:Glov_0560 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12Y66 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and H [...] (713 aa)
Mmah_0609COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR003594:IPR003661:IPR 000014:IPR000700:IPR001789:IPR005467; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12TG1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...] (510 aa)
Mmah_0625COGs: COG1340 Uncharacterized coiled-coil protein; KEGG: viral A-type inclusion protein; SPTR: Q12TE6 Phosphoserine phosphatase. (305 aa)
Mmah_0626KEGG: Viral A-type inclusion protein repeat; SPTR: Q12TE5 Putative uncharacterized protein. (214 aa)
Mmah_0647Protein of unknown function DUF357; COGs: COG1849 conserved hypothetical protein; InterPro IPR007155; PFAM: Protein of unknown function DUF357; SPTR: Q12XB6 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF357). (93 aa)
Mmah_0650Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR008279:IPR002192:IPR000121:IPR018274:IPR 019825:IPR010121; KEGG: gur:Gura_3671 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q12XB9 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding doma [...] (885 aa)
Mmah_0670RIO-like kinase; COGs: COG1718 Serine/threonine protein kinase involved in cell cycle control; InterProIPR018934:IPR000687:IPR008266:IPR000719:IPR 018935; KEGG: hypothetical protein; K07178 RIO kinase 1; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; SPTR: Q12XD7 Putative uncharacterized protein; PFAM: RIO1 family. (263 aa)
tgtAArchaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (491 aa)
Mmah_0677COGs: COG1340 Uncharacterized coiled-coil protein; KEGG: viral A-type inclusion protein; SPTR: Q12XE8 Phosphoserine phosphatase. (284 aa)
Mmah_0681Protein of unknown function DUF75; COGs: COG1938 protein of ATP-grasp superfamily; InterPro IPR002766:IPR004425; PFAM: protein of unknown function DUF75; SPTR: Q12XF7 Putative uncharacterized protein; PFAM: PAC2 family; TIGRFAM: conserved hypothetical protein TIGR00161. (263 aa)
Mmah_0689ERCC4 domain protein; COGs: COG1111 ERCC4-like helicase; InterProIPR006166:IPR000445:IPR011545:IPR001650:IPR 006935:IPR014001:IPR014021; KEGG: hypothetical protein; K10896 fanconi anemia group M protein; PFAM: ERCC4 domain protein; helix-hairpin-helix motif; DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q12XG3 ERCC4-like helicase; PFAM: Helicase conserved C-terminal domain; ERCC4 domain; DEAD/DEAH box helicase. (754 aa)
glySglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (585 aa)
Mmah_0701Hypothetical protein. (76 aa)
pfdBPrefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (121 aa)
Mmah_0747Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: hha:Hhal_1873 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Q8TNA2 Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2). (503 aa)
Mmah_0761COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR020471:IPR001395:IPR001450:IPR017900; KEGG: dat:HRM2_04090 putative aldo/keto reductase; PFAM: aldo/keto reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8PVL5 Oxidoreductase, ALDO/KETO reductase family; PFAM: Aldo/keto reductase family. (378 aa)
Mmah_0777DEAD/DEAH box helicase domain protein; COGs: COG1202 Superfamily II helicase; InterPro IPR001650:IPR011545:IPR014001:IPR014021; KEGG: similar to CG7972-PA; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q12ZD6 DEAD/DEAH box helicase-like protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. (827 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1056 aa)
Mmah_0788COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR003200:IPR002805; KEGG: abu:Abu_2184 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; SPTR: Q12ZC5 Putative uncharacterized protein; PFAM: Phosphoribosyltransferase; TIGRFAM: conserved hypothetical protein TIGR00303; Belongs to the UPF0284 family. (351 aa)
psmAProteasome endopeptidase complex, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (256 aa)
rrp4Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (255 aa)
Mmah_0813SPTR: Q8TLV4 Predicted protein. (72 aa)
Mmah_0821COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: dma:DMR_09640 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12Y17 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (575 aa)
Mmah_0831COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003594:IPR013656:IPR 013767:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: gur:Gura_2014 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor [...] (962 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (634 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (824 aa)
Mmah_0875Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (216 aa)
Mmah_0891TPR repeat-containing protein; InterProIPR001440:IPR013105:IPR003107:IPR019734:IPR 013026; KEGG: hypothetical protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat; RNA-processing protein HAT helix repeating-containing protein; SPTR: Q8PTJ5 Putative uncharacterized protein; PFAM: Tetratricopeptide repeat. (1022 aa)
Mmah_0904KEGG: viral A-type inclusion protein; SPTR: Q12VB6 Putative uncharacterized protein. (519 aa)
Mmah_0908COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013767:IPR003594:IPR000014:IPR 000700:IPR005467; KEGG: nmu:Nmul_A1289 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Q2Y4W7 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (366 aa)
Mmah_0911Putative PAS/PAC sensor protein; InterPro IPR013655:IPR013767:IPR000014:IPR000700; KEGG: ppd:Ppro_2652 histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Q12XC9 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (486 aa)
Mmah_0912COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: gem:GM21_1199 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kinase [...] (736 aa)
Mmah_0924ATP binding protein; COGs: COG2102 ATPase of PP-loop superfamily; InterPro IPR001962:IPR002761; KEGG: similar to GA13952-PA; PFAM: protein of unknown function DUF71 ATP-binding region; asparagine synthase; SPTR: Q12YM5 Putative uncharacterized protein; TIGRFAM: ATP binding protein; PFAM: Asparagine synthase; ATP-binding region; TIGRFAM: MJ0570-related uncharacterized domain; conserved hypothetical protein TIGR00289; asparagine synthase (glutamine-hydrolyzing). (690 aa)
Mmah_0931Hypothetical protein; SPTR: Q12XY1 Putative uncharacterized protein. (133 aa)
Mmah_0967Hypothetical protein; SPTR: Q12XR5 Putative uncharacterized protein. (298 aa)
Mmah_0974Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: pca:Pcar_0299 two component sensor histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XR0 Multi-PAS sensor; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box. (1043 aa)
Mmah_0976SPTR: Q12XQ8 Methanol:corrinoid methyltransferase; PFAM: Methanol-cobalamin methyltransferase B subunit. (461 aa)
Mmah_0996COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594:IPR005467; KEGG: gur:Gura_1729 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (370 aa)
Mmah_1023COGs: COG1605 Chorismate mutase; InterPro IPR002701:IPR010950; KEGG: mxa:MXAN_3221 chorismate mutase/prephenate dehydratase; PFAM: Chorismate mutase; SPTR: Q12XK1 Chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase type II; TIGRFAM: chorismate mutase, archaeal type. (94 aa)
Mmah_1042COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296:IPR003356:IPR002052:IPR004546; KEGG: vfi:VF_A0535 DNA methylase M; PFAM: N-6 DNA methylase; SPTR: A3UMI1 Type I restriction-modification system methylation subunit; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM). (494 aa)
Mmah_1044Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: vei:Veis_3129 restriction modification system DNA specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: Q57594 Type-1 restriction enzyme MjaXIP specificity protein; PFAM: Type I restriction modification DNA specificity domain. (414 aa)
Mmah_1063COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR004010:IPR003594:IPR003660:IPR 003661:IPR005467; KEGG: dal:Dalk_1747 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12YI4 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (637 aa)
Mmah_1068KEGG: sfu:Sfum_0244 hypothetical protein; SPTR: Q12ZF1 Putative uncharacterized protein. (113 aa)
Mmah_1079COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR008279:IPR002192; KEGG: dat:HRM2_42990 PpsA8; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: B8GDM6 Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (712 aa)
Mmah_1084Hexapaptide repeat-containing transferase; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: mxa:MXAN_3783 hexapaptide repeat-containing transferase; SPTR: Q12X27 Putative uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats). (169 aa)
Mmah_1100DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR001650:IPR011545:IPR014001:IPR014021:IPR 000629:IPR014014; KEGG: dvm:DvMF_2125 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: B8GGY3 DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (431 aa)
Mmah_1143Regulatory protein MarR; InterPro IPR000835; KEGG: hypothetical protein; PFAM: regulatory protein MarR; SPTR: Q12Y47 Transcriptional regulator, MarR family. (195 aa)
Mmah_1146InterPro IPR013096:IPR001387; KEGG: ppd:Ppro_0474 XRE family transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: A9A664 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix. (190 aa)
Mmah_1151COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR003660:IPR 000700:IPR005467:IPR000014; KEGG: ppd:Ppro_3009 hypothetical protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XN1 Multisensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRF [...] (727 aa)
cdhCacetyl-CoA decarbonylase/synthase beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (465 aa)
Mmah_1175Magnesium chelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: gur:Gura_0774 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Q8TTP1 Putative uncharacterized protein; PFAM: CobN/Magnesium Chelatase. (1747 aa)
tfeTranscription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (164 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (737 aa)
Mmah_1198Protein of unknown function DUF460; COGs: COG2433 conserved hypothetical protein; InterPro IPR007408; KEGG: myosin heavy chain, clone; PFAM: Protein of unknown function DUF460; SPTR: Q8PSJ9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF460). (660 aa)
pfdAPrefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (143 aa)
Mmah_1250COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12U10 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...] (933 aa)
Mmah_1282UspA domain protein; InterPro IPR006015:IPR006016; KEGG: ppd:Ppro_3112 UspA domain-containing protein; PFAM: UspA domain protein; SPTR: Q8TJ44 Universal stress protein; PFAM: Universal stress protein family. (284 aa)
Mmah_1284DGC domain protein; COGs: COG4273 conserved hypothetical protein; InterPro IPR014958; KEGG: dma:DMR_37400 hypothetical protein; PFAM: DGC domain protein; SPTR: Q8PYW1 Conserved protein; PFAM: DGC domain. (132 aa)
Mmah_1286Fe-S cluster domain protein; COGs: COG4871 conserved hypothetical protein; InterPro IPR007202; KEGG: dat:HRM2_00380 predicted Fe-S cluster protein; PFAM: Fe-S cluster domain protein; SPTR: A0B8P2 Fe-S cluster domain protein; PFAM: Bacterial regulatory protein, arsR family; Putative Fe-S cluster. (268 aa)
Mmah_1291Transcriptional regulator, PadR-like family; COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: dat:HRM2_46180 putative transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: O28080 Putative uncharacterized protein; PFAM: Transcriptional regulator PadR-like family. (130 aa)
Mmah_1297Transcriptional regulator, ArsR family; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR001845:IPR013216:IPR004033:IPR013217; KEGG: sfu:Sfum_0266 methyltransferase type 11; PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; regulatory protein ArsR; Methyltransferase type 12; SMART: regulatory protein ArsR; SPTR: Q8TJK1 UbiE/COQ5 methyltransferase; PFAM: Bacterial regulatory protein, arsR family; Methyltransferase domain. (349 aa)
Mmah_12993-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (248 aa)
Mmah_1301InterPro IPR018649; KEGG: dol:Dole_0430 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Q46BC1 Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2078). (78 aa)
Mmah_1311KEGG: hypothetical protein; SPTR: Q8PUU6 Conserved protein; PFAM: Cohesin domain. (408 aa)
cas1CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (405 aa)
Mmah_1314KEGG: hypothetical protein; SPTR: Q8PS37 Putative uncharacterized protein. (226 aa)
Mmah_1318KEGG: viral A-type inclusion protein. (184 aa)
Mmah_1328Type II secretion system F domain protein; COGs: COG1955 flagella assembly protein J; InterPro IPR018076; KEGG: dia:Dtpsy_2115 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Q12YP0 Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain. (741 aa)
Mmah_1333Hypothetical protein; InterPro IPR019734:IPR013026; KEGG: hypothetical protein; SPTR: Q12YM7 TPR repeat protein; PFAM: Tetratricopeptide repeat. (87 aa)
Mmah_1335KEGG: amc:MADE_02160 glycosyltransferase involved in cell wall biogenesis; SPTR: Q12XX4 Putative uncharacterized protein. (407 aa)
Mmah_1341COGs: COG1422 membrane protein; InterPro IPR002809; PFAM: protein of unknown function DUF106 transmembrane; SPTR: Q12ZS6 Putative uncharacterized protein; PFAM: Integral membrane protein DUF106. (212 aa)
Mmah_1367COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR019012; KEGG: similar to trimethylguanosine synthase homolog; PFAM: RNA cap guanine-N2 methyltransferase; SPTR: Q8PWT9 Methyltransferase; PFAM: RNA cap guanine-N2 methyltransferase. (350 aa)
Mmah_1377KEGG: pca:Pcar_0840 hypothetical protein; SPTR: Q8TUB5 Predicted protein. (106 aa)
Mmah_1394COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR013767:IPR003594:IPR 003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: dma:DMR_29900 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12X67 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B- [...] (729 aa)
argHCOGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR009049; KEGG: gur:Gura_0231 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Q8TR65 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (492 aa)
Mmah_1416Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: bpa:BPP2512 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: Q12TG2 Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. (340 aa)
atpDV-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (205 aa)
atpEH+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (183 aa)
Mmah_1449V-type ATPase 116 kDa subunit; COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: gur:Gura_0418 H(+)-transporting two-sector ATPase; PFAM: V-type ATPase 116 kDa subunit; SPTR: Q12WL6 V-type ATPase, 116 kDa subunit; PFAM: V-type ATPase 116kDa subunit family. (670 aa)
Mmah_1479COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR017998:IPR001844:IPR002423:IPR002194; KEGG: hypothetical protein; K09493 T-complex protein 1 subunit alpha; PFAM: chaperonin Cpn60/TCP-1; SPTR: Q8TSE1 Hsp60; PFAM: TCP-1/cpn60 chaperonin family. (536 aa)
Mmah_1503COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR004010:IPR013767:IPR 003594:IPR003660:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: amc:MADE_01755 putative two-component member protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: Q12ZM3 Sens [...] (732 aa)
corAMagnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (355 aa)
Mmah_1520NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: sat:SYN_02920 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Q12TJ7 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase. (207 aa)
cofH-2FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (356 aa)
dnaKChaperone protein DnaK; Acts as a chaperone. (623 aa)
Mmah_1633Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR000759:IPR013027:IPR000103:IPR001327:IPR 006004; KEGG: sat:SYN_00606 glutamate synthase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Q12WD0 Sulfide dehydrogenase (Flavoprotein) subunit SudA; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric. (458 aa)
leuSCOGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015413:IPR002300:IPR013155:IPR001412:IPR 004493; KEGG: leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); SPTR: Q12WA2 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, archaeal and cytosolic family. (961 aa)
Mmah_1666KEGG: hypothetical protein; SPTR: Q54G05 Putative leucine-rich repeat-containing protein DDB_G0290503. (386 aa)
Mmah_1676Dimethylamine corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: geo:Geob_2541 cobalamin B12-binding domain protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Q12W94 Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methylmalonyl-CoA mutase C-terminal domain. (203 aa)
Mmah_1701COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: EMB1441 (EMBRYO DEFECTIVE 1441); nucleic acid binding; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Q12W70 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). (662 aa)
Mmah_1708Protein of unknown function DUF75; COGs: COG2047 conserved hypothetical protein (ATP-grasp superfamily); InterPro IPR002766:IPR000568:IPR004426; PFAM: protein of unknown function DUF75; SPTR: Q12W63 Putative uncharacterized protein; PFAM: PAC2 family; TIGRFAM: conserved hypothetical protein TIGR00162. (259 aa)
eif2bTranslation initiation factor 2 subunit beta (aeIF-2b); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (202 aa)
uvrCExcinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (604 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (77 aa)
Mmah_1794InterPro IPR003761; KEGG: mmw:Mmwyl1_1147 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; SPTR: Q12VV5 Exodeoxyribonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit. (78 aa)
Mmah_1796Transposase, IS605 OrfB family; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095:IPR001959; KEGG: dno:DNO_0387 IS605 family transposase; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; SPTR: Q8TH26 Transposase; TIGRFAM: transposase, IS605 OrfB family; PFAM: Helix-turn-helix domain; Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region. (373 aa)
rad50SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (889 aa)
Mmah_1809InterPro IPR006162; KEGG: hypothetical protein; SPTR: Q12VW9 Putative uncharacterized protein. (235 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1173 aa)
Mmah_1811Condensin subunit ScpA; COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: dal:Dalk_5224 chromosome segregation and condensation protein ScpA; PFAM: chromosome segregation and condensation protein ScpA; SPTR: Q12VX1 Condensin subunit ScpA; PFAM: ScpA/B protein. (272 aa)
Mmah_1834InterPro IPR002746; PFAM: Protein of unknown function DUF61; SPTR: A3CXW3 Putative uncharacterized protein; PFAM: Protein of unknown function DUF61. (143 aa)
Mmah_1835Small GTP-binding protein; COGs: COG1163 GTPase; InterPro IPR006073:IPR002917:IPR004095:IPR005225; KEGG: developmentally regulated GTP-binding protein 1; PFAM: GTP-binding protein HSR1-related; TGS domain protein; SPTR: Q12VS9 Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain. (363 aa)
Mmah_1852Methanogenesis marker protein 15; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR002731:IPR008275:IPR017676; KEGG: dvl:Dvul_0705 putative CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: Q12UT8 CoA enzyme activase; TIGRFAM: methanogenesis marker protein 15; CoA-substrate-specific enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative; putative methanogenesis marker protein 15. (414 aa)
Mmah_1879Hypothetical protein; SPTR: Q12UW4 Putative uncharacterized protein. (61 aa)
Mmah_1899InterPro IPR019613; KEGG: dat:HRM2_23190 CbiP; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: A3K9F7 Putative uncharacterized protein; PFAM: Nickel uptake substrate-specific transmembrane region. (330 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
Mmah_1930KEGG: abpD; actin binding protein; SPTR: Q467T2 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (254 aa)
nacNascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (116 aa)
Mmah_1943Methyltransferase type 12; InterPro IPR013217; KEGG: dal:Dalk_0866 methyltransferase type 12; PFAM: Methyltransferase type 12; SPTR: Q12X06 Methyltransferase; PFAM: Ribosomal RNA adenine dimethylase. (287 aa)
Mmah_1948Multi-sensor signal transduction histidine kinase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR001789:IPR013767:IPR013656:IPR003661:IPR 000014:IPR000700:IPR005467; KEGG: dal:Dalk_3917 multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12V62 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator rece [...] (488 aa)
Mmah_1973Protein of unknown function DUF166; COGs: COG1810 conserved hypothetical protein; InterPro IPR003745; KEGG: dal:Dalk_4871 protein of unknown function DUF166; PFAM: Protein of unknown function DUF166; SPTR: Q8PXV6 Conserved protein; PFAM: Uncharacterized ArCR, COG1810. (222 aa)
Mmah_1978Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (237 aa)
lolDABC transporter related protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (226 aa)
Mmah_1995COGs: COG0417 DNA polymerase elongation subunit (family B); InterProIPR017966:IPR006134:IPR006133:IPR006172:IPR 017964:IPR004578; KEGG: CaJ7_0319; hypothetical protein; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase B; SPTR: Q12VE4 DNA polymerase; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). (918 aa)
Mmah_1998COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013656:IPR013767:IPR 003594:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; KEGG: tcx:Tcr_1913 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8PV00 Sensor protein; TIGRFAM: PAS sensor p [...] (632 aa)
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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