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HPT1_1 HPT1_1 IMH3_1 IMH3_1 AMD1_1 AMD1_1 PDE2_0 PDE2_0 ADK1 ADK1 inlI_1 inlI_1 ADE17_0 ADE17_0 HAM1_0 HAM1_0 PDE2_1 PDE2_1 GUK1_0 GUK1_0 ADE13_1 ADE13_1 HAM1_1 HAM1_1 GUA1_0 GUA1_0 Cantr_10510 Cantr_10510 GUA1_1 GUA1_1 ADO1 ADO1 ADK2 ADK2 PDE1 PDE1 APT1_0 APT1_0 AMD1_0 AMD1_0 IMH3_0 IMH3_0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HPT1_1Hypoxanthine-guanine phosphoribosyltransferase. (213 aa)
IMH3_1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
AMD1_1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (791 aa)
PDE2_0Phosphodiesterase. (561 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (248 aa)
inlI_1Internalin-I. (542 aa)
ADE17_0Bifunctional purine biosynthesis protein ADE17. (588 aa)
HAM1_0Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
PDE2_1Phosphodiesterase. (561 aa)
GUK1_0Guanylate kinase. (191 aa)
ADE13_1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
HAM1_1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
GUA1_0GMP synthase [glutamine-hydrolyzing]. (530 aa)
Cantr_10510Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (428 aa)
GUA1_1GMP synthase [glutamine-hydrolyzing]. (530 aa)
ADO1Adenosine kinase. (347 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Belongs to the adenylate kinase family. (166 aa)
PDE13',5'-cyclic-nucleotide phosphodiesterase. (425 aa)
APT1_0Adenine phosphoribosyltransferase. (188 aa)
AMD1_0AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (790 aa)
IMH3_0Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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