STRINGSTRING
ELO2_1 ELO2_1 FAD12_1 FAD12_1 acpS_0 acpS_0 Cantr_09327 Cantr_09327 fabD_1 fabD_1 fabG_2 fabG_2 ACC1_1 ACC1_1 HTD2_1 HTD2_1 fabG_3 fabG_3 PAS2_1 PAS2_1 Cantr_08646 Cantr_08646 EHT1_1 EHT1_1 nuo-12_1 nuo-12_1 HTD2_0 HTD2_0 Sugct Sugct Cantr_07196 Cantr_07196 PAS2_0 PAS2_0 Cantr_07580 Cantr_07580 fabD_0 fabD_0 FAS2_1 FAS2_1 FAT1 FAT1 HYR3_3 HYR3_3 Cantr_06486 Cantr_06486 FAD12_0 FAD12_0 FAD12_2 FAD12_2 ACP1_1 ACP1_1 Cantr_05000 Cantr_05000 Cantr_04258 Cantr_04258 Cantr_04550 Cantr_04550 OLE1_2 OLE1_2 SCS7_1 SCS7_1 ELOVL3_1 ELOVL3_1 nuo-12_0 nuo-12_0 HYR3_2 HYR3_2 EHT1_0 EHT1_0 acpS_1 acpS_1 ACP1_0 ACP1_0 Cantr_02823 Cantr_02823 OLE1_1 OLE1_1 ELO2_0 ELO2_0 hpo-8_1 hpo-8_1 Cantr_02531 Cantr_02531 Cantr_02641 Cantr_02641 ACC1_0 ACC1_0 SCS7_0 SCS7_0 RBR3_1 RBR3_1 HYR3_0 HYR3_0 fabG_1 fabG_1 IFF5 IFF5 PHS1_0 PHS1_0 hpo-8_0 hpo-8_0 ELOVL3_0 ELOVL3_0 OLE1_0 OLE1_0 FAS1 FAS1 FAS2_0 FAS2_0 Cantr_00007 Cantr_00007 ELO2_2 ELO2_2 ELO2_3 ELO2_3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELO2_1Elongation of fatty acids protein. (289 aa)
FAD12_1Delta(12) fatty acid desaturase. (435 aa)
acpS_0Holo-[acyl-carrier-protein] synthase. (136 aa)
Cantr_09327Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (353 aa)
fabD_1Malonyl CoA-acyl carrier protein transacylase. (326 aa)
fabG_23-oxoacyl-[acyl-carrier-protein] reductase FabG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (209 aa)
ACC1_1Acetyl-CoA carboxylase. (2223 aa)
HTD2_1Hydroxyacyl-thioester dehydratase type 2, mitochondrial. (293 aa)
fabG_33-oxoacyl-[acyl-carrier-protein] reductase FabG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (201 aa)
PAS2_1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (242 aa)
Cantr_08646S5A_REDUCTASE domain-containing protein. (312 aa)
EHT1_1Medium-chain fatty acid ethyl ester synthase/esterase 2. (426 aa)
nuo-12_1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (137 aa)
HTD2_0Hydroxyacyl-thioester dehydratase type 2, mitochondrial. (293 aa)
SugctSuccinate--hydroxymethylglutarate CoA-transferase. (548 aa)
Cantr_07196Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (389 aa)
PAS2_0Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (242 aa)
Cantr_07580Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (353 aa)
fabD_0Malonyl CoA-acyl carrier protein transacylase. (326 aa)
FAS2_13-oxoacyl-[acyl-carrier-protein] reductase. (1878 aa)
FAT1Very long-chain fatty acid transport protein. (639 aa)
HYR3_3Hyphally regulated cell wall protein 3. (961 aa)
Cantr_064863-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (433 aa)
FAD12_0Delta(12) fatty acid desaturase. (423 aa)
FAD12_2Delta(12) fatty acid desaturase. (435 aa)
ACP1_1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (116 aa)
Cantr_05000S5A_REDUCTASE domain-containing protein. (312 aa)
Cantr_04258AB hydrolase-1 domain-containing protein. (471 aa)
Cantr_04550Protein phosphatase; Belongs to the PP2C family. (611 aa)
OLE1_2Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (527 aa)
SCS7_1Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (384 aa)
ELOVL3_1Elongation of fatty acids protein. (350 aa)
nuo-12_0Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (135 aa)
HYR3_2Hyphally regulated cell wall protein 3. (1315 aa)
EHT1_0Medium-chain fatty acid ethyl ester synthase/esterase 2. (426 aa)
acpS_1Holo-[acyl-carrier-protein] synthase. (136 aa)
ACP1_0Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (116 aa)
Cantr_02823AB hydrolase-1 domain-containing protein. (471 aa)
OLE1_1Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (527 aa)
ELO2_0Elongation of fatty acids protein. (289 aa)
hpo-8_1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (204 aa)
Cantr_02531Protein phosphatase; Belongs to the PP2C family. (611 aa)
Cantr_02641Hyphal_reg_CWP domain-containing protein. (3050 aa)
ACC1_0Acetyl-CoA carboxylase. (2223 aa)
SCS7_0Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (385 aa)
RBR3_1Cell wall protein RBR3. (3040 aa)
HYR3_0Hyphally regulated cell wall protein 3. (1922 aa)
fabG_13-oxoacyl-[acyl-carrier-protein] reductase FabG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (210 aa)
IFF5Cell wall protein IFF5. (1814 aa)
PHS1_0Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (200 aa)
hpo-8_0Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (204 aa)
ELOVL3_0Elongation of fatty acids protein. (350 aa)
OLE1_0Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (488 aa)
FAS13-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase. (2039 aa)
FAS2_03-oxoacyl-[acyl-carrier-protein] reductase. (1886 aa)
Cantr_000073-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (433 aa)
ELO2_2Elongation of fatty acids protein. (339 aa)
ELO2_3Elongation of fatty acids protein. (339 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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