STRINGSTRING
ERG24_1 ERG24_1 ERG20_1 ERG20_1 ERG7_1 ERG7_1 PACTA PACTA ERG2_0 ERG2_0 HMG_0 HMG_0 ERG26 ERG26 ERG3_0 ERG3_0 ERG6_1 ERG6_1 MCR1 MCR1 Cantr_06888 Cantr_06888 ERG25_0 ERG25_0 ERG8 ERG8 Cantr_07482 Cantr_07482 ERG25_1 ERG25_1 NCP1 NCP1 ERG2_1 ERG2_1 ERG3_1 ERG3_1 HMG_1 HMG_1 NCP1-2 NCP1-2 ERG25_2 ERG25_2 Cantr_09426 Cantr_09426 ERG2_2 ERG2_2 ERG12_0 ERG12_0 ERG27_1 ERG27_1 ERG2_3 ERG2_3 ERG12_1 ERG12_1 ERG6_0 ERG6_0 ERG1 ERG1 ERG4 ERG4 ERG11 ERG11 CYC2 CYC2 Cantr_01290 Cantr_01290 ERG13 ERG13 ERG27_0 ERG27_0 Cytb5 Cytb5 ERG9_0 ERG9_0 ERG24_0 ERG24_0 PACTB PACTB ERG20_0 ERG20_0 ERG7_0 ERG7_0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERG24_1Delta(14)-sterol reductase. (443 aa)
ERG20_1Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (351 aa)
ERG7_1Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (728 aa)
PACTAAcetyl-CoA acetyltransferase IA; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ERG2_0C-8 sterol isomerase. (217 aa)
HMG_03-hydroxy-3-methylglutaryl coenzyme A reductase. (1042 aa)
ERG26Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating. (319 aa)
ERG3_0Delta(7)-sterol 5(6)-desaturase; Belongs to the sterol desaturase family. (392 aa)
ERG6_1Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (376 aa)
MCR1NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (211 aa)
Cantr_06888Uncharacterized protein. (70 aa)
ERG25_0Methylsterol monooxygenase; Belongs to the sterol desaturase family. (321 aa)
ERG8Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (420 aa)
Cantr_07482Uncharacterized protein. (219 aa)
ERG25_1Methylsterol monooxygenase; Belongs to the sterol desaturase family. (306 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (679 aa)
ERG2_1C-8 sterol isomerase. (217 aa)
ERG3_1Delta(7)-sterol 5(6)-desaturase; Belongs to the sterol desaturase family. (392 aa)
HMG_13-hydroxy-3-methylglutaryl coenzyme A reductase. (1039 aa)
NCP1-2NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (679 aa)
ERG25_2Methylsterol monooxygenase; Belongs to the sterol desaturase family. (306 aa)
Cantr_09426Uncharacterized protein. (219 aa)
ERG2_2C-8 sterol isomerase. (217 aa)
ERG12_0Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (432 aa)
ERG27_13-keto-steroid reductase. (346 aa)
ERG2_3C-8 sterol isomerase. (218 aa)
ERG12_1Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (432 aa)
ERG6_0Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (376 aa)
ERG1Squalene monooxygenase. (497 aa)
ERG4Delta(24(24(1)))-sterol reductase. (469 aa)
ERG11Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (528 aa)
CYC2Cytochrome c mitochondrial import factor CYC2. (540 aa)
Cantr_01290Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
ERG133-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (449 aa)
ERG27_03-keto-steroid reductase. (346 aa)
Cytb5Cytochrome b5; Belongs to the cytochrome b5 family. (129 aa)
ERG9_0Squalene synthase. (446 aa)
ERG24_0Delta(14)-sterol reductase. (443 aa)
PACTBAcetyl-CoA acetyltransferase IB; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ERG20_0Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (351 aa)
ERG7_0Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (728 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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