STRINGSTRING
RFA1_1 RFA1_1 SGS1_1 SGS1_1 Cantr_05742 Cantr_05742 SHQ1_1 SHQ1_1 Cantr_05741 Cantr_05741 Cantr_05436 Cantr_05436 CTF8_1 CTF8_1 MTC6_1 MTC6_1 HTB2_2 HTB2_2 NHP2_0 NHP2_0 Cantr_08210 Cantr_08210 HTB2_3 HTB2_3 RRM3_1 RRM3_1 CTF18_1 CTF18_1 NHP2_1 NHP2_1 CBF5_0 CBF5_0 GAR1_0 GAR1_0 GAR1_1 GAR1_1 PIF1_1 PIF1_1 CBF5_1 CBF5_1 MTC6_0 MTC6_0 PUS4 PUS4 DCC1 DCC1 CTF8_0 CTF8_0 NOP10_0 NOP10_0 RVB2_0 RVB2_0 RRM3_0 RRM3_0 CTF18_0 CTF18_0 PIF1_0 PIF1_0 RVB2_1 RVB2_1 YRF1-6_1 YRF1-6_1 SHQ1_0 SHQ1_0 SGS1_0 SGS1_0 RFA1_0 RFA1_0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RFA1_1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa)
SGS1_1ATP-dependent helicase SGS1. (1171 aa)
Cantr_05742Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (279 aa)
SHQ1_1Protein SHQ1. (518 aa)
Cantr_05741Uncharacterized protein. (143 aa)
Cantr_05436Uncharacterized protein. (418 aa)
CTF8_1Chromosome transmission fidelity protein 8. (149 aa)
MTC6_1Maintenance of telomere capping protein 6. (591 aa)
HTB2_2Histone H2B; Belongs to the histone H2B family. (130 aa)
NHP2_0Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (159 aa)
Cantr_08210Uncharacterized protein. (425 aa)
HTB2_3Histone H2B; Belongs to the histone H2B family. (130 aa)
RRM3_1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (609 aa)
CTF18_1Chromosome transmission fidelity protein 18. (826 aa)
NHP2_1Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (159 aa)
CBF5_0Centromere/microtubule-binding protein CBF5. (475 aa)
GAR1_0H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (204 aa)
GAR1_1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (200 aa)
PIF1_1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (749 aa)
CBF5_1Centromere/microtubule-binding protein CBF5. (475 aa)
MTC6_0Maintenance of telomere capping protein 6. (591 aa)
PUS4tRNA pseudouridine synthase 4. (386 aa)
DCC1Sister chromatid cohesion protein DCC1. (345 aa)
CTF8_0Chromosome transmission fidelity protein 8. (150 aa)
NOP10_0H/ACA ribonucleoprotein complex subunit 3. (59 aa)
RVB2_0RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (478 aa)
RRM3_0ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (609 aa)
CTF18_0Chromosome transmission fidelity protein 18. (826 aa)
PIF1_0ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (749 aa)
RVB2_1RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (478 aa)
YRF1-6_1Y' element ATP-dependent helicase protein 1 copy 6. (1405 aa)
SHQ1_0Protein SHQ1. (519 aa)
SGS1_0ATP-dependent helicase SGS1. (1173 aa)
RFA1_0Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (616 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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