STRINGSTRING
ISW1 ISW1 RAD53_0 RAD53_0 ESA1_0 ESA1_0 ISW2_0 ISW2_0 MRE11 MRE11 DUN1 DUN1 RAD50_0 RAD50_0 Cantr_08783 Cantr_08783 HTB2_3 HTB2_3 UBX7_1 UBX7_1 VPS64_1 VPS64_1 HTB2_2 HTB2_2 RAD50_1 RAD50_1 ISW2_1 ISW2_1 DMA2 DMA2 TEL1 TEL1 VPS64_0 VPS64_0 UBX7_0 UBX7_0 ubi3 ubi3 RAD53_1 RAD53_1 ESA1_1 ESA1_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ISW1ISWI chromatin-remodeling complex ATPase ISW1. (812 aa)
RAD53_0Serine/threonine-protein kinase RAD53. (693 aa)
ESA1_0Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (534 aa)
ISW2_0ISWI chromatin-remodeling complex ATPase ISW2. (1064 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (627 aa)
DUN1DNA damage response protein kinase DUN1. (504 aa)
RAD50_0DNA repair protein RAD50. (1307 aa)
Cantr_08783Uncharacterized protein. (81 aa)
HTB2_3Histone H2B; Belongs to the histone H2B family. (130 aa)
UBX7_1UBX domain-containing protein 7. (564 aa)
VPS64_1Vacuolar protein sorting-associated protein 64. (698 aa)
HTB2_2Histone H2B; Belongs to the histone H2B family. (130 aa)
RAD50_1DNA repair protein RAD50. (1307 aa)
ISW2_1ISWI chromatin-remodeling complex ATPase ISW2. (1064 aa)
DMA2E3 ubiquitin-protein ligase DMA2. (427 aa)
TEL1Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2686 aa)
VPS64_0Vacuolar protein sorting-associated protein 64. (703 aa)
UBX7_0UBX domain-containing protein 7. (556 aa)
ubi3Ubiquitin-40S ribosomal protein S27a. (151 aa)
RAD53_1Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (750 aa)
ESA1_1Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (534 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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