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IMH3_1 IMH3_1 pgmA_0 pgmA_0 PRS4_0 PRS4_0 ADE13_0 ADE13_0 DEG1_1 DEG1_1 CPD1_0 CPD1_0 INO80_0 INO80_0 ADE6_0 ADE6_0 GDA1_1 GDA1_1 PNP1_1 PNP1_1 ADE2_1 ADE2_1 PUS1 PUS1 HNT2_2 HNT2_2 MAM3_1 MAM3_1 inlI_1 inlI_1 HNT2_3 HNT2_3 ADK1 ADK1 PRM15_1 PRM15_1 YSA1_1 YSA1_1 ISW2_1 ISW2_1 PHO2_1 PHO2_1 IRC5_1 IRC5_1 PRS5_1 PRS5_1 AMD1_1 AMD1_1 DPH6_1 DPH6_1 PPX1_1 PPX1_1 RNR2_2 RNR2_2 CDC19_1 CDC19_1 DAL2_1 DAL2_1 ADE1_1 ADE1_1 RNR2_3 RNR2_3 HPT1_1 HPT1_1 WHS11_1 WHS11_1 Cantr_04569 Cantr_04569 ADE8_1 ADE8_1 APA1_1 APA1_1 scs3_1 scs3_1 allB1_1 allB1_1 DAL1_1 DAL1_1 Cantr_04359 Cantr_04359 PHO2_3 PHO2_3 YLF2 YLF2 ISN1_0 ISN1_0 RNR1_1 RNR1_1 Cantr_03470 Cantr_03470 RNR2_0 RNR2_0 PRS1_1 PRS1_1 IMH3_0 IMH3_0 APA1_0 APA1_0 ADE1_0 ADE1_0 IRC5_0 IRC5_0 Cantr_02512 Cantr_02512 AMD1_0 AMD1_0 PRS5_0 PRS5_0 RNR2_1 RNR2_1 allB1_0 allB1_0 APT1_0 APT1_0 ADE8_0 ADE8_0 YND1 YND1 Cantr_03618 Cantr_03618 ADE1_2 ADE1_2 HNT1_0 HNT1_0 Cantr_04053 Cantr_04053 AAH1_1 AAH1_1 HBR1_0 HBR1_0 ADE4 ADE4 PDE2_0 PDE2_0 OLA1_0 OLA1_0 WHS11_0 WHS11_0 CDC19_0 CDC19_0 DAL2_0 DAL2_0 DPH6_0 DPH6_0 URIC URIC HPT1_0 HPT1_0 scs3_0 scs3_0 AAH1_0 AAH1_0 Cantr_03032 Cantr_03032 Cantr_02720 Cantr_02720 Cantr_02110 Cantr_02110 RNR1_0 RNR1_0 PPX1_0 PPX1_0 DAL1_0 DAL1_0 ade5 ade5 Cantr_02146 Cantr_02146 CYR1_1 CYR1_1 GUD1 GUD1 Cantr_01204 Cantr_01204 CSP37_0 CSP37_0 MSC1 MSC1 sD sD PDE1 PDE1 NIT2 NIT2 PNP1_0 PNP1_0 ISW1 ISW1 PRS1_2 PRS1_2 DEG1_0 DEG1_0 NIK1 NIK1 Cantr_01314 Cantr_01314 Cantr_01068 Cantr_01068 Cantr_01103 Cantr_01103 ADK2 ADK2 CYR1_0 CYR1_0 Cantr_01373 Cantr_01373 ISW2_0 ISW2_0 ADO1 ADO1 MET3_1 MET3_1 HNT1_1 HNT1_1 GDA1_0 GDA1_0 PRS1_0 PRS1_0 NDK1 NDK1 PHO2_7 PHO2_7 GUA1_1 GUA1_1 PRM15_0 PRM15_0 Cantr_10510 Cantr_10510 YSA1_0 YSA1_0 ADE2_0 ADE2_0 Cantr_10494 Cantr_10494 HNT2_1 HNT2_1 MAM3_0 MAM3_0 HNT2_0 HNT2_0 GUA1_0 GUA1_0 PHO2_6 PHO2_6 GUK1_1 GUK1_1 HAM1_1 HAM1_1 MET3_0 MET3_0 pgmA_1 pgmA_1 Cantr_09913 Cantr_09913 DDP1_1 DDP1_1 Cantr_09897 Cantr_09897 INO80_1 INO80_1 CSP37_1 CSP37_1 ADE6_1 ADE6_1 rnr-1 rnr-1 ADE17_1 ADE17_1 CPD1_1 CPD1_1 ADE13_1 ADE13_1 GUK1_0 GUK1_0 PDE2_1 PDE2_1 HBR1_1 HBR1_1 OLA1_1 OLA1_1 ISN1_1 ISN1_1 HAM1_0 HAM1_0 DDP1_0 DDP1_0 RNR1_2 RNR1_2 PBY1 PBY1 DAL3 DAL3 ADE17_0 ADE17_0
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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IMH3_1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
pgmA_0Phosphoglucomutase; Belongs to the phosphohexose mutase family. (560 aa)
PRS4_0Ribose-phosphate pyrophosphokinase 4. (319 aa)
ADE13_0Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
DEG1_1tRNA pseudouridine(38/39) synthase. (442 aa)
CPD1_02',3'-cyclic-nucleotide 3'-phosphodiesterase. (246 aa)
INO80_0Putative DNA helicase INO80. (1363 aa)
ADE6_0Phosphoribosylformylglycinamidine synthase. (1339 aa)
GDA1_1Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (582 aa)
PNP1_1Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (307 aa)
ADE2_1Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (568 aa)
PUS1tRNA pseudouridine synthase 1. (491 aa)
HNT2_2Bis(5'-adenosyl)-triphosphatase. (186 aa)
MAM3_1Protein MAM3. (755 aa)
inlI_1Internalin-I. (542 aa)
HNT2_3Bis(5'-adenosyl)-triphosphatase. (186 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (248 aa)
PRM15_1Phosphoribomutase. (615 aa)
YSA1_1ADP-ribose pyrophosphatase. (210 aa)
ISW2_1ISWI chromatin-remodeling complex ATPase ISW2. (1064 aa)
PHO2_1Acid phosphatase. (325 aa)
IRC5_1Putative ATP-dependent helicase IRC5. (800 aa)
PRS5_1Ribose-phosphate pyrophosphokinase 5. (440 aa)
AMD1_1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (791 aa)
DPH6_1Diphthine--ammonia ligase. (621 aa)
PPX1_1Exopolyphosphatase. (407 aa)
RNR2_2Ribonucleoside-diphosphate reductase small chain 1. (415 aa)
CDC19_1Pyruvate kinase; Belongs to the pyruvate kinase family. (508 aa)
DAL2_1Allantoicase. (340 aa)
ADE1_1Phosphoribosylaminoimidazole-succinocarboxamide synthase. (294 aa)
RNR2_3Ribonucleoside-diphosphate reductase small chain 1. (395 aa)
HPT1_1Hypoxanthine-guanine phosphoribosyltransferase. (213 aa)
WHS11_1White colony protein WHS11. (67 aa)
Cantr_04569Metallophos domain-containing protein. (573 aa)
ADE8_1Phosphoribosylglycinamide formyltransferase. (223 aa)
APA1_1Protein APA1. (318 aa)
scs3_1FIT family protein scs3. (292 aa)
allB1_1Putative allantoinase 1. (186 aa)
DAL1_1Allantoinase. (590 aa)
Cantr_043595-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (147 aa)
PHO2_3Acid phosphatase. (324 aa)
YLF2Obg-like ATPase. (410 aa)
ISN1_0IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (446 aa)
RNR1_1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (865 aa)
Cantr_03470Uncharacterized protein. (988 aa)
RNR2_0Ribonucleoside-diphosphate reductase small chain 1. (395 aa)
PRS1_1Ribose-phosphate pyrophosphokinase 1. (320 aa)
IMH3_0Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
APA1_0Protein APA1. (318 aa)
ADE1_0Phosphoribosylaminoimidazole-succinocarboxamide synthase. (294 aa)
IRC5_0Putative ATP-dependent helicase IRC5. (801 aa)
Cantr_02512Metallophos domain-containing protein. (573 aa)
AMD1_0AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (790 aa)
PRS5_0Ribose-phosphate pyrophosphokinase 5. (444 aa)
RNR2_1Ribonucleoside-diphosphate reductase small chain 1. (419 aa)
allB1_0Putative allantoinase 1. (186 aa)
APT1_0Adenine phosphoribosyltransferase. (188 aa)
ADE8_0Phosphoribosylglycinamide formyltransferase. (223 aa)
YND1Golgi apyrase; Belongs to the GDA1/CD39 NTPase family. (600 aa)
Cantr_03618Uncharacterized protein. (988 aa)
ADE1_2Bifunctional purine biosynthetic protein ADE1. (626 aa)
HNT1_0Hit family protein 1. (149 aa)
Cantr_04053Putative glutamine amidotransferase-like protein C13C5.04. (286 aa)
AAH1_1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (355 aa)
HBR1_0Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (243 aa)
ADE4Amidophosphoribosyltransferase. (484 aa)
PDE2_0Phosphodiesterase. (561 aa)
OLA1_0Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
WHS11_0White colony protein WHS11. (67 aa)
CDC19_0Pyruvate kinase; Belongs to the pyruvate kinase family. (508 aa)
DAL2_0Allantoicase. (340 aa)
DPH6_0Diphthine--ammonia ligase. (621 aa)
URICUricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (266 aa)
HPT1_0Hypoxanthine-guanine phosphoribosyltransferase. (213 aa)
scs3_0FIT family protein scs3. (292 aa)
AAH1_0Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (355 aa)
Cantr_03032Putative glutamine amidotransferase-like protein C13C5.04. (286 aa)
Cantr_027205-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (144 aa)
Cantr_02110Metallophos domain-containing protein. (351 aa)
RNR1_0Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (865 aa)
PPX1_0Exopolyphosphatase. (407 aa)
DAL1_0Allantoinase. (428 aa)
ade5Phosphoribosylglycinamide formyltransferase. (157 aa)
Cantr_02146Metallophos domain-containing protein. (359 aa)
CYR1_1Adenylate cyclase. (1696 aa)
GUD1Putative guanine deaminase. (527 aa)
Cantr_01204Putative MFS-type transporter PB1E7.08c. (524 aa)
CSP37_0Cell surface protein. (343 aa)
MSC1Meiotic sister chromatid recombination protein 1. (794 aa)
sDAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (200 aa)
PDE13',5'-cyclic-nucleotide phosphodiesterase. (425 aa)
NIT2Putative hydrolase NIT2. (299 aa)
PNP1_0Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (307 aa)
ISW1ISWI chromatin-remodeling complex ATPase ISW1. (812 aa)
PRS1_2Ribose-phosphate pyrophosphokinase 1. (320 aa)
DEG1_0tRNA pseudouridine(38/39) synthase. (440 aa)
NIK1Histidine protein kinase NIK1. (1138 aa)
Cantr_01314Putative MFS-type transporter PB1E7.08c. (462 aa)
Cantr_01068Metallophos domain-containing protein. (351 aa)
Cantr_01103Metallophos domain-containing protein. (359 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Belongs to the adenylate kinase family. (166 aa)
CYR1_0Adenylate cyclase. (1703 aa)
Cantr_01373Putative MFS-type transporter PB1E7.08c. (512 aa)
ISW2_0ISWI chromatin-remodeling complex ATPase ISW2. (1064 aa)
ADO1Adenosine kinase. (347 aa)
MET3_1Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (524 aa)
HNT1_1Hit family protein 1. (149 aa)
GDA1_0Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (582 aa)
PRS1_0Ribose-phosphate pyrophosphokinase 1. (407 aa)
NDK1Nucleoside diphosphate kinase. (151 aa)
PHO2_7Acid phosphatase. (325 aa)
GUA1_1GMP synthase [glutamine-hydrolyzing]. (530 aa)
PRM15_0Phosphoribomutase. (615 aa)
Cantr_10510Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (428 aa)
YSA1_0ADP-ribose pyrophosphatase. (222 aa)
ADE2_0Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (568 aa)
Cantr_10494OBG-type G domain-containing protein. (414 aa)
HNT2_1Bis(5'-adenosyl)-triphosphatase. (186 aa)
MAM3_0Protein MAM3. (756 aa)
HNT2_0Bis(5'-adenosyl)-triphosphatase. (186 aa)
GUA1_0GMP synthase [glutamine-hydrolyzing]. (530 aa)
PHO2_6Acid phosphatase. (324 aa)
GUK1_1Guanylate kinase. (191 aa)
HAM1_1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
MET3_0Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (524 aa)
pgmA_1Phosphoglucomutase; Belongs to the phosphohexose mutase family. (560 aa)
Cantr_09913OBG-type G domain-containing protein. (414 aa)
DDP1_1Diphosphoinositol polyphosphate phosphohydrolase DDP1. (184 aa)
Cantr_09897Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (428 aa)
INO80_1Putative DNA helicase INO80. (1359 aa)
CSP37_1Cell surface protein. (343 aa)
ADE6_1Phosphoribosylformylglycinamidine synthase. (1339 aa)
rnr-1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (817 aa)
ADE17_1Bifunctional purine biosynthesis protein ADE17. (588 aa)
CPD1_12',3'-cyclic-nucleotide 3'-phosphodiesterase. (246 aa)
ADE13_1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
GUK1_0Guanylate kinase. (191 aa)
PDE2_1Phosphodiesterase. (561 aa)
HBR1_1Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (241 aa)
OLA1_1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
ISN1_1IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (446 aa)
HAM1_0Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
DDP1_0Diphosphoinositol polyphosphate phosphohydrolase DDP1. (184 aa)
RNR1_2Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (817 aa)
PBY1Putative tubulin--tyrosine ligase PBY1. (697 aa)
DAL3Ureidoglycolate lyase. (167 aa)
ADE17_0Bifunctional purine biosynthesis protein ADE17. (588 aa)
Your Current Organism:
Candida viswanathii
NCBI taxonomy Id: 5486
Other names: ATCC 22981, C. viswanathii, CBS 4024, CCRC 21330, CCRC:21330, Candida lodderae, Candida viswanathii Viswanathan & H.S. Randhawa ex R.S. Sandhu & H.S. Randhawa, 2015, DBVPG 6189, IFO 10321, JCM 9567, NRRL Y-6660
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