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fruA_1 fruA_1 lacC lacC fruB fruB ptsH ptsH ptsI_2 ptsI_2 ptsI_1 ptsI_1 AOE38939.1 AOE38939.1 lutR_2 lutR_2 licB licB gmuD_2 gmuD_2 gmuC gmuC chbA chbA ybbH_2 ybbH_2 bglA_1 bglA_1 licR_2 licR_2 glmU_1 glmU_1 glmS glmS mtlD_2 mtlD_2 mtlA mtlA murQ murQ murP_2 murP_2 AOE39878.1 AOE39878.1 AOE39879.1 AOE39879.1 glkA glkA AOE39882.1 AOE39882.1 ptsO ptsO ptsN ptsN glmM_2 glmM_2 AOE40047.1 AOE40047.1 fruA_2 fruA_2 manP manP mak mak nagD nagD mlc_3 mlc_3 nagA nagA nagB nagB ptsG_6 ptsG_6 chb_1 chb_1 manA_2 manA_2 manX manX manY manY manZ manZ cutC cutC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fruA_1PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
lacC1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (312 aa)
fruBBifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
ptsHPTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
ptsI_2Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
ptsI_1Phosphoenolpyruvate--protein phosphotransferase PtsP; Member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (748 aa)
AOE38939.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
lutR_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
licBPTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
gmuD_26-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (475 aa)
gmuCPTS lactose transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (449 aa)
chbAMolecular chaperone TorD; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
ybbH_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
bglA_16-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. (479 aa)
licR_2Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
glmU_1UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
mtlD_2Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. (382 aa)
mtlAPTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (303 aa)
murP_2PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
AOE39878.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOE39879.1N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
glkAROK family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AOE39882.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
ptsOPhosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
ptsNPTS IIA-like nitrogen-regulatory protein PtsN; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
glmM_2Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
AOE40047.1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
fruA_2PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
manPDNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
makFructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
nagDUMP phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
mlc_3Transcriptional regulator; Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
ptsG_6PTS N-acetyl glucosamine transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
chb_1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (883 aa)
manA_2Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
manXPTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
manYPTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
manZPTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (250 aa)
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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