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galE galE galF galF glk glk crr_1 crr_1 glmU_1 glmU_1 glmS glmS wecB wecB wecC wecC murB murB pgi pgi murQ murQ murP_2 murP_2 AOE39879.1 AOE39879.1 murA murA glmM_2 glmM_2 AOE40047.1 AOE40047.1 mak mak AOE40524.1 AOE40524.1 nagA nagA nagB nagB ptsG_6 ptsG_6 pgm_1 pgm_1 galK galK galT_2 galT_2 chb_1 chb_1 ptsG_5 ptsG_5 nagZ_2 nagZ_2 ptsG_2 ptsG_2 manA_2 manA_2 ptsG_1 ptsG_1 rffG_1 rffG_1 tuaD tuaD galU galU manX manX manY manY manZ manZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
galEUDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa)
galFGalU regulator GalF; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
crr_1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
glmU_1UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
wecCCatalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (419 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (548 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (303 aa)
murP_2PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
AOE39879.1N-acetylglucosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
glmM_2Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
AOE40047.1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
makFructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AOE40524.1Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1253 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
ptsG_6PTS N-acetyl glucosamine transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (675 aa)
pgm_1Phosphoglucomutase, alpha-D-glucose phosphate-specific; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (382 aa)
galT_2Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (348 aa)
chb_1beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (883 aa)
ptsG_5PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
nagZ_2beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ptsG_2PTS sugar transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
manA_2Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
ptsG_1PTS maltose transporter subunit IICB; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
rffG_1Protein CapI; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
tuaDUDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
galUUTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
manXPTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
manYPTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
manZPTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
Your Current Organism:
Pantoea agglomerans
NCBI taxonomy Id: 549
Other names: ATCC 27155, Bacillus milletiae, Bacterium herbicola, CCUG 539, CFBP 3845, CIP 57.51, DSM 3493, Enterobacter agglomerans, Erwinia herbicola, Erwinia milletiae, ICMP 12534, ICPB 3435, NBRC 102470, NCTC 9381, P. agglomerans, Pantoea herbicola, Pantoea sp. SL1_M5, Pseudomonas herbicola, bacterium G33-1
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