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Fbal_0055 Fbal_0055 pckA pckA ppc ppc Fbal_0370 Fbal_0370 Fbal_0371 Fbal_0371 Fbal_0372 Fbal_0372 Fbal_0376 Fbal_0376 Fbal_0431 Fbal_0431 Fbal_0456 Fbal_0456 Fbal_0457 Fbal_0457 Fbal_0458 Fbal_0458 Fbal_0468 Fbal_0468 Fbal_0469 Fbal_0469 aceK aceK eno eno oadG oadG Fbal_0862 Fbal_0862 Fbal_0863 Fbal_0863 Fbal_0934 Fbal_0934 accA accA Fbal_0998 Fbal_0998 Fbal_1019 Fbal_1019 Fbal_1024 Fbal_1024 Fbal_1148 Fbal_1148 Fbal_1149 Fbal_1149 Fbal_1380 Fbal_1380 Fbal_1381 Fbal_1381 fabH fabH Fbal_1396 Fbal_1396 Fbal_1397 Fbal_1397 Fbal_1399 Fbal_1399 Fbal_1490 Fbal_1490 acsA acsA maeA maeA Fbal_1767 Fbal_1767 Fbal_1806 Fbal_1806 Fbal_1852 Fbal_1852 fabA fabA Fbal_1967 Fbal_1967 Fbal_1990 Fbal_1990 Fbal_1991 Fbal_1991 Fbal_2117 Fbal_2117 Fbal_2201 Fbal_2201 Fbal_2202 Fbal_2202 Fbal_2260 Fbal_2260 Fbal_2356 Fbal_2356 Fbal_2357 Fbal_2357 Fbal_2358 Fbal_2358 fabH-2 fabH-2 sucD sucD sucC sucC Fbal_2486 Fbal_2486 Fbal_2487 Fbal_2487 Fbal_2488 Fbal_2488 Fbal_2489 Fbal_2489 Fbal_2490 Fbal_2490 Fbal_2491 Fbal_2491 Fbal_2492 Fbal_2492 Fbal_2514 Fbal_2514 Fbal_2549 Fbal_2549 Fbal_2550 Fbal_2550 Fbal_2551 Fbal_2551 ackA ackA Fbal_2555 Fbal_2555 fabV fabV accD accD Fbal_2615 Fbal_2615 Fbal_2784 Fbal_2784 Fbal_2785 Fbal_2785 Fbal_2814 Fbal_2814 mdh mdh Fbal_3387 Fbal_3387 Fbal_3410 Fbal_3410 Fbal_3411 Fbal_3411 Fbal_3519 Fbal_3519 ilvA ilvA ilvD ilvD ilvE ilvE Fbal_3649 Fbal_3649 Fbal_3650 Fbal_3650 ilvC ilvC Fbal_3655 Fbal_3655 Fbal_3656 Fbal_3656 prpB prpB Fbal_3658 Fbal_3658 Aconitase Aconitase Fbal_3660 Fbal_3660 leuD leuD leuC leuC leuB leuB leuA leuA
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Fbal_0055NADPH-glutathione reductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR000103: IPR000815: IPR001327: IPR 004099: IPR012999: IPR006322; KEGG: slo:Shew_3660 glutathione reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A3UP40 Glutathione reductase; TIGRFAM: glutathione-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIG [...] (451 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (509 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa)
Fbal_03702-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
Fbal_0371Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (632 aa)
Fbal_0372COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR000759: IPR013027: IPR000103: IPR000815: IPR 001327: IPR004099: IPR002218: IPR012999: IPR006258; KEGG: shm:Shewmr7_3597 dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; SPTR: A2UYJ1 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-dis [...] (475 aa)
Fbal_0376Aconitase; COGs: COG1049 Aconitase B; InterPro IPR015929: IPR001030: IPR018136: IPR004406; KEGG: vpa:VP2495 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; SPTR: A3H377 Aconitate hydratase 2; TIGRFAM: aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (864 aa)
Fbal_0431Succinate semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010102; KEGG: swd:Swoo_3863 succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Succinate-semialdehyde dehydrogenase; SPTR: P25526 Succinate-semialdehyde dehydrogenase [NADP+]; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
Fbal_0456InterPro IPR018956; KEGG: shn:Shewana3_0401 fumarate reductase cytochrome b-556 subunit; PFAM: Fumarate reductase respiratory complex; SPTR: A2UYL7 Fumarate reductase respiratory complex, transmembrane subunit; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (234 aa)
Fbal_0457COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR004112: IPR006076: IPR003953: IPR003952: IPR 014006; KEGG: shn:Shewana3_0403 fumarate reductase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; PRIAM: Succinate dehydrogenase; SPTR: A2UYL5 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate redu [...] (653 aa)
Fbal_0458COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR001041: IPR006058: IPR004489; KEGG: lhk:LHK_02342 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; PRIAM: Succinate dehydrogenase; SPTR: A2UYL4 Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (244 aa)
Fbal_0468Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
Fbal_0469Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)
aceK(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (567 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa)
oadGSodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (75 aa)
Fbal_0862Oxaloacetate decarboxylase alpha subunit; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR003379: IPR000089: IPR001882: IPR 005776; KEGG: saz:Sama_1052 oxaloacetate decarboxylase; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; SPTR: A3UZN5 Oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme; TIGRFAM: oxaloacetate decarboxylase alpha subunit. (597 aa)
Fbal_0863Sodium ion-translocating decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa)
Fbal_0934COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: vvu:VV2_0869 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: A3XRZ9 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (506 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
Fbal_0998COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459: IPR000873; KEGG: swp:swp_3440 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A2V351 AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. (635 aa)
Fbal_1019Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010061; KEGG: saz:Sama_1376 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: A2V1P0 Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. (497 aa)
Fbal_1024Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002424: IPR002198: IPR013968; KEGG: swp:swp_3381 3-ketoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; SPTR: A2V1P5 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (253 aa)
Fbal_1148Aminotransferase class-III; COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814; KEGG: aha:AHA_0245 beta alanine--pyruvate transaminase; PFAM: aminotransferase class-III; SPTR: A0P1C1 Beta alanine-pyruvate transaminase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
Fbal_1149Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR010061; KEGG: aha:AHA_0246 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: A2V022 Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. (500 aa)
Fbal_1380Cytochrome c3; InterPro IPR011031; KEGG: sbp:Sbal223_2492 cytochrome c3; SPTR: A2V404 Cytochrome c3. (105 aa)
Fbal_1381Cytochrome c3; InterPro IPR011031; KEGG: shw:Sputw3181_1675 cytochrome c3; SPTR: A2V404 Cytochrome c3; PFAM: Class III cytochrome C family. (99 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa)
Fbal_1396COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR004410; KEGG: son:SO_2777 acyl carrier protein S-malonyltransferase; PFAM: Acyl transferase; SPTR: P0AAI9 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; malonate decarboxylase, epsilon subunit. (309 aa)
Fbal_13973-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
Fbal_13993-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
Fbal_1490COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670: IPR015590: IPR018211; KEGG: swd:Swoo_2241 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: A2V102 Iron-containing alcohol dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (868 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
maeACOGs: COG0281 Malic enzyme; InterPro IPR001891: IPR012302: IPR012301: IPR015884; KEGG: swp:swp_3875 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: B8CQT6 NAD-dependent malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (582 aa)
Fbal_1767Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (504 aa)
Fbal_1806COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027: IPR006076: IPR004792: IPR003953: IPR 011031: IPR010960; KEGG: sse:Ssed_3877 succinate dehydrogenase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; SPTR: Q07WU7 Fumarate reductase flavoprotein subunit; TIGRFAM: flavocytochrome c; PFAM: FAD binding domain; TIGRFAM: flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH su [...] (594 aa)
Fbal_1852D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: mmw:Mmwyl1_3029 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: A0ZAM6 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (330 aa)
fabA3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (179 aa)
Fbal_1967COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697; KEGG: sbm:Shew185_2128 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: A2V5D4 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
Fbal_1990Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804: IPR019818: IPR004439; KEGG: pmr:PMI0891 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: P08200 Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (417 aa)
Fbal_1991Isocitrate dehydrogenase, NADP-dependent; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: pin:Ping_0983 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A0Y1L4 Isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (752 aa)
Fbal_2117COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076: IPR003953: IPR006311; KEGG: sfr:Sfri_3694 twin-arginine translocation pathway signal; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; SPTR: A2UV06 Twin-arginine translocation pathway signal; PFAM: FAD binding domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. (559 aa)
Fbal_2201Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
Fbal_2202Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (270 aa)
Fbal_2260COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027: IPR002218: IPR006076: IPR004792: IPR 003953: IPR011031: IPR010960; KEGG: sfr:Sfri_2586 flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; SPTR: Q9Z4P0 Fumarate reductase flavoprotein subunit; TIGRFAM: flavocytochrome c; PFAM: FAD binding domain; TIGRFAM: flavocytochrome c; Belongs to the FAD-de [...] (588 aa)
Fbal_2356Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167: IPR000089: IPR001078; KEGG: saz:Sama_1711 dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: A2UZF7 Catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Bi [...] (515 aa)
Fbal_2357Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005476: IPR005475; KEGG: hch:HCH_03686 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit beta; PFAM: Transketolase central region; Transketolase domain protein; SPTR: A3JES1 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (325 aa)
Fbal_23583-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: saz:Sama_1709 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: A2UZF5 Dehydrogenase, E1 component; PFAM: Dehydrogenase E1 component. (394 aa)
fabH-23-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (359 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
Fbal_24862-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (398 aa)
Fbal_2487COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR001017: IPR005475: IPR011603; KEGG: slo:Shew_1655 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component; SPTR: A2V1H2 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (935 aa)
Fbal_2488COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR001041: IPR017900: IPR004489; KEGG: saz:Sama_1426 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: A2V1H3 Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (235 aa)
Fbal_2489COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027: IPR004112: IPR003953: IPR003952: IPR 014006: IPR011281; KEGG: asa:ASA_2359 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: A3WKB9 Succinate dehydrogenase; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; succinate [...] (586 aa)
Fbal_2490Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
Fbal_2491COGs: COG2009 Succinate dehydrogenase/fumarate reductase cytochrome b subunit; InterPro IPR000701: IPR018495: IPR014314; KEGG: spe:Spro_1263 succinate dehydrogenase cytochrome b556 large membrane subunit; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: P63725 Succinate dehydrogenase cytochrome b556 subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit. (125 aa)
Fbal_2492COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810: IPR010953; KEGG: shl:Shal_2494 type II citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: A2V1H7 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (428 aa)
Fbal_2514COGs: COG1254 Acylphosphatase; InterPro IPR020456: IPR001792: IPR017968; KEGG: sse:Ssed_2835 acylphosphatase; PFAM: acylphosphatase; SPTR: A1S579 Acylphosphatase; PFAM: Acylphosphatase. (90 aa)
Fbal_2549Hypothetical protein. (75 aa)
Fbal_2550COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150: IPR004184: IPR019777: IPR005949; KEGG: vch:VC1866 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: A3H1R9 Formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1. (760 aa)
Fbal_2551Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
Fbal_2555Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (711 aa)
fabVTrans-2-enoyl-CoA reductase (NAD(+)); Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (402 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
Fbal_2615COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014031: IPR014030: IPR018201; KEGG: vfm:VFMJ11_1826 3-oxoacyl-(acyl-carrier-protein) synthase 1; PFAM: Beta-ketoacyl synthase; SPTR: A3ELX7 3-oxoacyl-(Acyl-carrier-protein) synthase I; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (407 aa)
Fbal_2784COGs: COG2224 Isocitrate lyase; InterPro IPR000918; KEGG: pap:PSPA7_2573 isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; SPTR: A0Z837 Isocitrate lyase; PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase. (530 aa)
Fbal_2785COGs: COG2225 Malate synthase; InterPro IPR011076: IPR019830: IPR006252; KEGG: saz:Sama_2381 malate synthase; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: A2UVA6 Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (545 aa)
Fbal_2814COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804: IPR019818; KEGG: swp:swp_3606 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NAD(+)); SPTR: A2UVF1 Isocitrate/isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NAD-dependent, mitochondrial type; isopropylmalate/isohomocitrate dehydrogenases; isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (335 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
Fbal_3387Quinone oxidoreductase, YhdH/YhfP family; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154: IPR013149: IPR014188; KEGG: pin:Ping_1035 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: A3UZ76 Alcohol dehydrogenase; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family. (326 aa)
Fbal_3410COGs: COG3957 Phosphoketolase; InterPro IPR018969: IPR018970: IPR005593: IPR019790: IPR 019789; KEGG: son:SO_3542 putative phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; PRIAM: Phosphoketolase; SPTR: A2UZZ0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain. (788 aa)
Fbal_3411Formate C-acetyltransferase glycine radical; Acts as a radical domain for damaged PFL and possibly other radical proteins. (141 aa)
Fbal_3519Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); COGs: COG0281 Malic enzyme; InterPro IPR012302: IPR012301: IPR015884; KEGG: vha:VIBHAR_00051 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: A0Y278 Putative NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (435 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (508 aa)
ilvDCOGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581: IPR020558: IPR004404; KEGG: slo:Shew_0292 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: A3Q9L6 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (611 aa)
ilvEBranched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (323 aa)
Fbal_3649COGs: COG3978 Acetolactate synthase (isozyme II) small (regulatory) subunit; KEGG: sdn:Sden_3413 acetolactate synthase 2 regulatory subunit; SPTR: A2UYR6 Amino acid-binding ACT. (87 aa)
Fbal_3650Acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012000: IPR011766: IPR012001: IPR000399: IPR 012846; KEGG: shw:Sputw3181_3754 acetolactate synthase 2 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; SPTR: A2UYR7 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-termin [...] (548 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
Fbal_3655Protein of unknown function DUF523; COGs: COG1683 conserved hypothetical protein; InterPro IPR007553; KEGG: aha:AHA_4208 hypothetical protein; PFAM: protein of unknown function DUF523; SPTR: A3LHC0 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF523). (166 aa)
Fbal_3656Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: saz:Sama_3293 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: A2V3R9 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain. (222 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (290 aa)
Fbal_3658COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810: IPR011278; KEGG: maq:Maqu_1665 methylcitrate synthase; PFAM: Citrate synthase; PRIAM: 2-methylcitrate synthase; SPTR: A0Y5Y9 Type II citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family. (374 aa)
AconitaseAconitase; COGs: COG1048 Aconitase A; InterPro IPR001030: IPR000573: IPR012708; KEGG: avn:Avin_23230 2-methylisocitrate dehydratase, Fe/S-dependent; PFAM: aconitate hydratase domain protein; SPTR: A3JGL7 Aconitate hydratase; TIGRFAM: 2-methylisocitrate dehydratase, Fe/S-dependent; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: 2-methylisocitrate dehydratase, Fe/S-dependent; aconitate hydratase 1. (871 aa)
Fbal_36602-methylaconitate cis-trans isomerase; COGs: COG2828 conserved hypothetical protein; InterPro IPR007400: IPR012709; KEGG: aeh:Mlg_2602 methylitaconate delta2-delta3-isomerase; PFAM: protein of unknown function DUF453; SPTR: A2V3S3 Probable AcnD-accessory protein PrpF; TIGRFAM: AcnD-accessory protein PrpF; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. (391 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (365 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (517 aa)
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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