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Fbal_0110 Fbal_0110 Fbal_0131 Fbal_0131 coaD coaD coaA coaA coaE coaE Fbal_0468 Fbal_0468 Fbal_0479 Fbal_0479 Fbal_0842 Fbal_0842 accA accA Fbal_0998 Fbal_0998 Fbal_1001 Fbal_1001 Fbal_1093 Fbal_1093 Fbal_1311 Fbal_1311 acsA acsA Fbal_2028 Fbal_2028 Fbal_2248 Fbal_2248 Fbal_2486 Fbal_2486 ackA ackA Fbal_2555 Fbal_2555 accD accD Fbal_2729 Fbal_2729 Fbal_2794 Fbal_2794 Fbal_2934 Fbal_2934 Fbal_3672 Fbal_3672
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fbal_0110(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (701 aa)
Fbal_0131Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
coaACOGs: COG1072 Panthothenate kinase; InterPro IPR004566; KEGG: slo:Shew_0143 pantothenate kinase; SPTR: A3Q967 Pantothenate kinase; TIGRFAM: pantothenate kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type. (312 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa)
Fbal_0468Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
Fbal_0479Thioesterase superfamily protein; COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: slo:Shew_1159 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: A2UVA8 Thioesterase superfamily; PFAM: Thioesterase superfamily. (135 aa)
Fbal_0842(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (730 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
Fbal_0998COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459: IPR000873; KEGG: swp:swp_3440 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A2V351 AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. (635 aa)
Fbal_1001COGs: COG1946 Acyl-CoA thioesterase; InterPro IPR003703; KEGG: spl:Spea_2791 acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; SPTR: A2V360 Acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: Acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II. (291 aa)
Fbal_1093KEGG: vsp:VS_1720 hypothetical protein; SPTR: A3V0B5 Putative uncharacterized protein; PFAM: Region found in RelA / SpoT proteins. (255 aa)
Fbal_1311Glyoxalase/bleomycin resistance protein/dioxygenase; COGs: COG3324 protein related to lactoylglutathione lyase; InterPro IPR004360; KEGG: mmw:Mmwyl1_2654 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A2V316 Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (117 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
Fbal_2028RelA/SpoT domain protein; COGs: COG2357 conserved hypothetical protein; InterPro IPR007685; KEGG: vvu:VV1_2511 hypothetical protein; PFAM: RelA/SpoT domain protein; SPTR: A3IFZ1 Putative uncharacterized protein; PFAM: Region found in RelA / SpoT proteins. (235 aa)
Fbal_2248Glyoxalase/bleomycin resistance protein/dioxygenase; InterPro IPR004360: IPR018146; KEGG: vpa:VPA0108 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A3UQ92 Lactoylglutathione lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (161 aa)
Fbal_24862-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (398 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
Fbal_2555Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (711 aa)
accDacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
Fbal_2729Glyoxalase/bleomycin resistance protein/dioxygenase; COGs: COG3324 protein related to lactoylglutathione lyase; InterPro IPR004360; KEGG: saz:Sama_1387 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A2P2Z8 Putative uncharacterized protein. (126 aa)
Fbal_2794COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: amc:MADE_03154 putative exopolyphosphatase; PFAM: Ppx/GppA phosphatase; PRIAM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; SPTR: A3GPM3 Exopolyphosphatase; PFAM: Ppx/GppA phosphatase family; Belongs to the GppA/Ppx family. (495 aa)
Fbal_2934Thioesterase superfamily protein; COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: asa:ASA_2794 acyl-CoA thioester hydrolase; PFAM: thioesterase superfamily protein; SPTR: A3GY56 Acyl-CoA hydrolase; PFAM: Thioesterase superfamily. (130 aa)
Fbal_3672KEGG: vha:VIBHAR_05694 hypothetical protein; SPTR: A3UWU7 Putative uncharacterized protein; PFAM: Nitrous oxide-stimulated promoter. (130 aa)
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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