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Aazo_0051 Aazo_0051 Aazo_0133 Aazo_0133 ilvC ilvC ilvD ilvD Aazo_0404 Aazo_0404 Aazo_0809 Aazo_0809 Aazo_0840 Aazo_0840 accD accD leuB leuB Aazo_1096 Aazo_1096 ilvA ilvA Aazo_1372 Aazo_1372 Aazo_1656 Aazo_1656 ppc ppc Aazo_1774 Aazo_1774 Aazo_2787 Aazo_2787 accA accA Aazo_4126 Aazo_4126 leuA leuA Aazo_4800 Aazo_4800 leuD leuD leuC leuC acsA acsA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Aazo_0051acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
Aazo_0133PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; protein of unknown function DUF205; PEP-utilising protein mobile region; KEGG: npu:Npun_F1309 pyruvate phosphate dikinase, PEP/pyruvate-binding. (956 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
ilvDTIGRFAM: dihydroxy-acid dehydratase; KEGG: npu:Npun_R3783 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (563 aa)
Aazo_0404TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: ava:Ava_2713 citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family. (378 aa)
Aazo_0809acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (176 aa)
Aazo_0840PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; KEGG: ava:Ava_3533 acetolactate synthase; Belongs to the TPP enzyme family. (547 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (317 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa)
Aazo_1096TIGRFAM: acetolactate synthase, small subunit; KEGG: npu:Npun_F1890 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein. (172 aa)
ilvAThreonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa)
Aazo_1372KEGG: npu:Npun_F0430 homocitrate synthase; TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (377 aa)
Aazo_1656Malate dehydrogenase (oxaloacetate-decarboxylating); KEGG: ana:alr4596 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; amino acid-binding ACT domain protein. (463 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1017 aa)
Aazo_1774Pyruvate, water dikinase; KEGG: npu:Npun_R6166 PEP-utilizing enzyme; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; pyruvate phosphate dikinase PEP/pyruvate-binding. (780 aa)
Aazo_2787KEGG: pab:PAB0286 trans-homoaconitate synthase; PFAM: pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (394 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (360 aa)
Aazo_4126KEGG: npu:Npun_R1735 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding. (638 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (530 aa)
Aazo_4800KEGG: ana:alr3522 putative alpha-isopropylmalate/homocitrate synthase family transferase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (552 aa)
leuD3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa)
Your Current Organism:
Nostoc azollae
NCBI taxonomy Id: 551115
Other names: '. azollae' 0708, 'Nostoc azollae' 0708, Anabaena azollae 0708
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