STRINGSTRING
ARF53489.1 ARF53489.1 mltG mltG ARF54412.1 ARF54412.1 sepF sepF ARF54886.1 ARF54886.1 ARF54887.1 ARF54887.1 sepF-2 sepF-2 ARF54889.1 ARF54889.1 ARF54890.1 ARF54890.1 ftsZ ftsZ ftsQ ftsQ murG murG ARF54894.1 ARF54894.1 murD murD mraY mraY murF murF murE murE ARF59384.1 ARF59384.1 ARF54898.1 ARF54898.1 rsmH rsmH ARF54900.1 ARF54900.1 ARF54901.1 ARF54901.1 ARF54902.1 ARF54902.1 ARF59385.1 ARF59385.1 ARF55202.1 ARF55202.1 ARF55315.1 ARF55315.1 ARF55317.1 ARF55317.1 ARF55318.1 ARF55318.1 ARF55319.1 ARF55319.1 ARF55320.1 ARF55320.1 ARF55321.1 ARF55321.1 ARF55322.1 ARF55322.1 ARF55323.1 ARF55323.1 ARF55325.1 ARF55325.1 ARF55327.1 ARF55327.1 ARF59478.1 ARF59478.1 ARF55390.1 ARF55390.1 murA murA ARF55549.1 ARF55549.1 ARF55550.1 ARF55550.1 ftsE ftsE ARF55552.1 ARF55552.1 ARF55875.1 ARF55875.1 murB murB ARF59571.1 ARF59571.1 ARF56138.1 ARF56138.1 ARF56407.1 ARF56407.1 mltG-2 mltG-2 ARF56637.1 ARF56637.1 ARF56764.1 ARF56764.1 ARF56778.1 ARF56778.1 ARF57129.1 ARF57129.1 ARF57195.1 ARF57195.1 ARF57334.1 ARF57334.1 murG-2 murG-2 ddl ddl ARF57755.1 ARF57755.1 ARF57796.1 ARF57796.1 B1H19_30415 B1H19_30415 murC murC ARF59010.1 ARF59010.1 ARF59012.1 ARF59012.1 ARF59013.1 ARF59013.1 def-3 def-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARF53489.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (753 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (583 aa)
ARF54412.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (859 aa)
sepFCell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (149 aa)
ARF54886.1Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ARF54887.1YggT family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
sepF-2Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (206 aa)
ARF54889.1YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (240 aa)
ARF54890.1Laccase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (252 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (410 aa)
ftsQCell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (297 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa)
ARF54894.1Putative lipid II flippase FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (446 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (477 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (354 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (477 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (594 aa)
ARF59384.1Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
ARF54898.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
rsmH16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (322 aa)
ARF54900.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
ARF54901.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ARF54902.1DUF58 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ARF59385.1Transglutaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (803 aa)
ARF55202.1Rod shape-determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ARF55315.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
ARF55317.1B12-binding domain-containing radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
ARF55318.1Metal-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
ARF55319.1Rod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (403 aa)
ARF55320.1Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
ARF55321.1Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ARF55322.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (310 aa)
ARF55323.1Rod shape-determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ARF55325.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
ARF55327.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
ARF59478.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
ARF55390.1Rod shape-determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (448 aa)
ARF55549.1Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
ARF55550.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (303 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (229 aa)
ARF55552.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (63 aa)
ARF55875.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (464 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (351 aa)
ARF59571.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
ARF56138.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
ARF56407.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (891 aa)
mltG-2Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (275 aa)
ARF56637.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
ARF56764.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
ARF56778.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ARF57129.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
ARF57195.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)
ARF57334.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (659 aa)
murG-2Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (374 aa)
ddlD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (378 aa)
ARF57755.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ARF57796.1Bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
B1H19_30415Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (466 aa)
ARF59010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
ARF59012.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ARF59013.1Ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
def-3Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (185 aa)
Your Current Organism:
Streptomyces gilvosporeus
NCBI taxonomy Id: 553510
Other names: S. gilvosporeus
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