STRINGSTRING
ARF56144.1 ARF56144.1 ARF58987.1 ARF58987.1 bioA bioA ARF58912.1 ARF58912.1 ARF58796.1 ARF58796.1 ARF58790.1 ARF58790.1 ARF58684.1 ARF58684.1 ARF58612.1 ARF58612.1 ARF58280.1 ARF58280.1 ARF58232.1 ARF58232.1 ARF58138.1 ARF58138.1 ARF57800.1 ARF57800.1 rrf rrf ARF57694.1 ARF57694.1 ARF57682.1 ARF57682.1 B1H19_28060 B1H19_28060 glyA-3 glyA-3 glyA-2 glyA-2 ARF57256.1 ARF57256.1 ARF57165.1 ARF57165.1 ARF57150.1 ARF57150.1 glyA glyA ARF57052.1 ARF57052.1 serC serC ARF59649.1 ARF59649.1 ARF56556.1 ARF56556.1 ARF56539.1 ARF56539.1 pat pat ARF56435.1 ARF56435.1 ARF56426.1 ARF56426.1 ARF59577.1 ARF59577.1 kynU kynU ARF56177.1 ARF56177.1 hemL hemL ARF55937.1 ARF55937.1 ARF55805.1 ARF55805.1 ARF54951.1 ARF54951.1 ARF54940.1 ARF54940.1 hisC hisC ARF54830.1 ARF54830.1 ARF54763.1 ARF54763.1 ARF54742.1 ARF54742.1 ARF54738.1 ARF54738.1 ARF54734.1 ARF54734.1 ARF54662.1 ARF54662.1 ARF54474.1 ARF54474.1 argD argD ARF59310.1 ARF59310.1 gcvP gcvP ARF54069.1 ARF54069.1 kbl kbl ARF53717.1 ARF53717.1 ARF53628.1 ARF53628.1 ARF53545.1 ARF53545.1 ARF53274.1 ARF53274.1 ARF53228.1 ARF53228.1 ARF59159.1 ARF59159.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARF56144.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ARF58987.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (441 aa)
ARF58912.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
ARF58796.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
ARF58790.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
ARF58684.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ARF58612.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
ARF58280.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
ARF58232.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
ARF58138.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
ARF57800.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
rrf5S ribosomal RNA; Derived by automated computational analysis using gene prediction method: cmsearch. (225 aa)
ARF57694.14-aminobutyrate--2-oxoglutarate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
ARF57682.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
B1H19_28060Alpha/beta hydrolase; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (453 aa)
ARF57256.1Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
ARF57165.1Aminotransferase; Broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ARF57150.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
ARF57052.1Ornithine--oxo-acid transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa)
ARF59649.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
ARF56556.1Ornithine--oxo-acid transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
ARF56539.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
patHistidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (359 aa)
ARF56435.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
ARF56426.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
ARF59577.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (427 aa)
ARF56177.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
ARF55937.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
ARF55805.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
ARF54951.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (469 aa)
ARF54940.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (372 aa)
ARF54830.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ARF54763.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
ARF54742.1Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
ARF54738.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
ARF54734.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ARF54662.1Pyridoxal-dependent decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
ARF54474.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (412 aa)
ARF59310.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
ARF54069.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
ARF53717.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
ARF53628.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (352 aa)
ARF53545.1Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
ARF53274.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
ARF53228.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
ARF59159.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
Your Current Organism:
Streptomyces gilvosporeus
NCBI taxonomy Id: 553510
Other names: S. gilvosporeus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.