(30 nodes) ClpP/crotonase-like domain superfamily network (Streptomyces gilvosporeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	clpP-2	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (212 aa)
	clpP-3	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (200 aa)
	ARF54004.1	Hydrogenase maturation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
	ARF59287.1	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
	ARF59293.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	ARF54717.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
	clpP	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (224 aa)
	clpP-4	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (204 aa)
	ARF59481.1	methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
	ARF55549.1	Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
	ARF55731.1	Peptidase S41; Degrades oligopeptides; Belongs to the peptidase S41B family. (1140 aa)
	ARF55833.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
	ARF55844.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	ARF56963.1	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
	ARF56966.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	ARF57131.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
	ARF57134.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
	ARF57264.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (266 aa)
	ARF57499.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	ARF57581.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	ARF57923.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
	ARF57948.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa)
	ARF58000.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
	ARF58576.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (734 aa)
	ARF58596.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	ARF58655.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	ARF58940.1	Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
	clpP-5	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (211 aa)
	ARF59057.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
	ARF59063.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)

Your Current Organism:

Streptomyces gilvosporeus

NCBI taxonomy Id: 553510
Other names: S. gilvosporeus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF54004.1	ARF59287.1	B1H19_07215	B1H19_07560	Hydrogenase maturation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.543
ARF54717.1	ARF55833.1	B1H19_11310	B1H19_18060	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.783
ARF54717.1	ARF56966.1	B1H19_11310	B1H19_24835	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.768
ARF54717.1	ARF57948.1	B1H19_11310	B1H19_30495	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.585
ARF54717.1	ARF59063.1	B1H19_11310	B1H19_37150	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.624
ARF55833.1	ARF54717.1	B1H19_18060	B1H19_11310	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.783
ARF55844.1	ARF56966.1	B1H19_18120	B1H19_24835	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
ARF55844.1	ARF57264.1	B1H19_18120	B1H19_26600	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.915
ARF55844.1	ARF58655.1	B1H19_18120	B1H19_34715	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.927
ARF55844.1	ARF59057.1	B1H19_18120	B1H19_37110	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
ARF55844.1	ARF59063.1	B1H19_18120	B1H19_37150	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.931
ARF55844.1	ARF59293.1	B1H19_18120	B1H19_07975	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
ARF56963.1	ARF56966.1	B1H19_24820	B1H19_24835	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.828
ARF56963.1	ARF57948.1	B1H19_24820	B1H19_30495	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.582
ARF56963.1	ARF58576.1	B1H19_24820	B1H19_34205	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.582
ARF56963.1	ARF59287.1	B1H19_24820	B1H19_07560	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
ARF56966.1	ARF54717.1	B1H19_24835	B1H19_11310	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.768
ARF56966.1	ARF55844.1	B1H19_24835	B1H19_18120	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
ARF56966.1	ARF56963.1	B1H19_24835	B1H19_24820	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase carboxyltransferase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.828
ARF56966.1	ARF57264.1	B1H19_24835	B1H19_26600	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.938