STRINGSTRING
Toce_0374 Toce_0374 Toce_0375 Toce_0375 Toce_0376 Toce_0376 Toce_0377 Toce_0377 Toce_0378 Toce_0378 Toce_0379 Toce_0379 Toce_0380 Toce_0380 Toce_0381 Toce_0381 Toce_0385 Toce_0385 Toce_0386 Toce_0386 Toce_0387 Toce_0387 larC larC Toce_0390 Toce_0390
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Toce_0374Quinolinate phosphoribosyl transferase; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638; KEGG: mta:Moth_1779 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Nicotinate-nucleotide pyrophosphorylase (Carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain. (266 aa)
Toce_0375InterPro IPR001453; KEGG: mta:Moth_1778 molybdopterin binding domain-containing protein; PFAM: molybdopterin binding domain; SPTR: Molybdopterin binding domain; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (307 aa)
Toce_0376COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. (257 aa)
Toce_0377Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (291 aa)
Toce_03784-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (339 aa)
Toce_0379BFD domain protein (2Fe-2S)-binding domain protein; COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR017896:IPR017900:IPR007419; KEGG: chy:CHY_1274 iron-sulfur cluster-binding protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Iron-sulfur cluster-binding protein; PFAM: 4Fe-4S binding domain; BFD-like [2Fe-2S] binding domain. (204 aa)
Toce_0380KEGG: mta:Moth_1773 hypothetical protein; SPTR: Putative uncharacterized protein. (482 aa)
Toce_0381Benzoate transporter; COGs: COG3135 Uncharacterized protein involved in benzoate metabolism; InterPro IPR003016:IPR004711; KEGG: mta:Moth_1772 benzoate transporter; PFAM: Benzoate membrane transport protein; SPTR: Benzoate transporter; TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; TIGRFAM: benzoate transporter. (416 aa)
Toce_0385Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: mta:Moth_1780 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator. (261 aa)
Toce_0386PP-loop domain protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR011063; KEGG: chy:CHY_1281 hypothetical protein; PFAM: PP-loop domain protein; SPTR: ExsB family protein; PFAM: NAD synthase; TIGRFAM: conserved hypothetical protein TIGR00268. (278 aa)
Toce_03871-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: cth:Cthe_0368 NCAIR mutase (PurE)-related protein; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: NCAIR mutase (PurE)-related protein; PFAM: AIR carboxylase. (256 aa)
larCProtein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (391 aa)
Toce_0390Metal dependent phosphohydrolase; COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006675:IPR006674; KEGG: chy:CHY_1871 HDIG domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (193 aa)
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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