(12 nodes) Fibroblast growth factor receptor activity, and Phospholipase C-mediated cascade: FGFR1 network (Platysternon megacephalum)

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Your Input:
	DR999_PMT22274	Receptor protein-tyrosine kinase. (472 aa)
	DR999_PMT17322	Neural proliferation differentiation and control protein 1. (929 aa)
	DR999_PMT16832	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	DR999_PMT10231	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
	DR999_PMT08938	Fibroblast growth factor receptor. (845 aa)
	DR999_PMT07038	Fibroblast growth factor receptor. (878 aa)
	DR999_PMT05773	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	DR999_PMT03545	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	DR999_PMT05529	Male-specific lethal 1-like protein. (508 aa)
	DR999_PMT05275	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
	DR999_PMT06927	Fibroblast growth factor receptor. (830 aa)
	DR999_PMT05369	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)

Your Current Organism:

Platysternon megacephalum

NCBI taxonomy Id: 55544
Other names: P. megacephalum, Platysternon macrocephalus, big-headed turtle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR999_PMT03545	DR999_PMT05275	A0A4D9ENX9	A0A4D9ET73	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.662
DR999_PMT03545	DR999_PMT05369	A0A4D9ENX9	A0A4D9EWJ0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.661
DR999_PMT03545	DR999_PMT05529	A0A4D9ENX9	A0A4D9ESX2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Male-specific lethal 1-like protein.	0.712
DR999_PMT03545	DR999_PMT05773	A0A4D9ENX9	A0A4D9EL40	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.683
DR999_PMT03545	DR999_PMT06927	A0A4D9ENX9	A0A4D9EW72	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.954
DR999_PMT03545	DR999_PMT07038	A0A4D9ENX9	A0A4D9EEK3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.952
DR999_PMT03545	DR999_PMT08938	A0A4D9ENX9	A0A4D9EDX6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.952
DR999_PMT03545	DR999_PMT10231	A0A4D9ENX9	A0A4D9E964	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.628
DR999_PMT03545	DR999_PMT16832	A0A4D9ENX9	A0A4D9DXF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.776
DR999_PMT03545	DR999_PMT17322	A0A4D9ENX9	A0A4D9DW21	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neural proliferation differentiation and control protein 1.	0.964
DR999_PMT03545	DR999_PMT22274	A0A4D9ENX9	A0A4D9DLU7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein-tyrosine kinase.	0.954
DR999_PMT05275	DR999_PMT03545	A0A4D9ET73	A0A4D9ENX9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.662
DR999_PMT05275	DR999_PMT05369	A0A4D9ET73	A0A4D9EWJ0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.692
DR999_PMT05275	DR999_PMT05529	A0A4D9ET73	A0A4D9ESX2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Male-specific lethal 1-like protein.	0.755
DR999_PMT05275	DR999_PMT05773	A0A4D9ET73	A0A4D9EL40	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.723
DR999_PMT05275	DR999_PMT06927	A0A4D9ET73	A0A4D9EW72	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.930
DR999_PMT05275	DR999_PMT07038	A0A4D9ET73	A0A4D9EEK3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.921
DR999_PMT05275	DR999_PMT08938	A0A4D9ET73	A0A4D9EDX6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.921
DR999_PMT05275	DR999_PMT10231	A0A4D9ET73	A0A4D9E964	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.779
DR999_PMT05275	DR999_PMT16832	A0A4D9ET73	A0A4D9DXF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.796