(16 nodes) MET activates PTPN11, and Insulin receptor signaling pathway network (Platysternon megacephalum)

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Your Input:
	DR999_PMT20500	Rhodopsin kinase-like. (642 aa)
	DR999_PMT16034	Adapter molecule crk. (728 aa)
	DR999_PMT11075	Insulin receptor substrate 1. (1193 aa)
	DR999_PMT12797	Growth factor receptor-bound protein 2. (217 aa)
	DR999_PMT10882	Tyrosine-protein kinase receptor. (1354 aa)
	DR999_PMT10758	Putative gastrointestinal growth factor xP4-like. (727 aa)
	DR999_PMT09389	Tyrosine-protein phosphatase non-receptor type. (466 aa)
	DR999_PMT11285	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
	DR999_PMT06208	Receptor protein-tyrosine kinase. (966 aa)
	DR999_PMT03467	Tyrosine-protein kinase receptor. (1363 aa)
	DR999_PMT08247	Unconventional myosin-Vb. (1382 aa)
	DR999_PMT02237	GPN-loop GTPase 3. (679 aa)
	DR999_PMT00142	Mastermind-like protein 3. (610 aa)
	DR999_PMT02648	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	DR999_PMT02426	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	DR999_PMT00995	Relaxin receptor 1-like. (1182 aa)

Your Current Organism:

Platysternon megacephalum

NCBI taxonomy Id: 55544
Other names: P. megacephalum, Platysternon macrocephalus, big-headed turtle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR999_PMT00142	DR999_PMT00995	A0A4D9F019	A0A4D9F744	Mastermind-like protein 3.	Relaxin receptor 1-like.	0.722
DR999_PMT00142	DR999_PMT02237	A0A4D9F019	A0A4D9ETJ0	Mastermind-like protein 3.	GPN-loop GTPase 3.	0.851
DR999_PMT00142	DR999_PMT02426	A0A4D9F019	A0A4D9F3F6	Mastermind-like protein 3.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.992
DR999_PMT00142	DR999_PMT02648	A0A4D9F019	A0A4D9F2U9	Mastermind-like protein 3.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.992
DR999_PMT00142	DR999_PMT03467	A0A4D9F019	A0A4D9ERL5	Mastermind-like protein 3.	Tyrosine-protein kinase receptor.	0.797
DR999_PMT00142	DR999_PMT06208	A0A4D9F019	A0A4D9EJ96	Mastermind-like protein 3.	Receptor protein-tyrosine kinase.	0.826
DR999_PMT00142	DR999_PMT08247	A0A4D9F019	A0A4D9ESK1	Mastermind-like protein 3.	Unconventional myosin-Vb.	0.998
DR999_PMT00142	DR999_PMT09389	A0A4D9F019	A0A4D9EAR8	Mastermind-like protein 3.	Tyrosine-protein phosphatase non-receptor type.	0.477
DR999_PMT00142	DR999_PMT10758	A0A4D9F019	A0A4D9E920	Mastermind-like protein 3.	Putative gastrointestinal growth factor xP4-like.	0.925
DR999_PMT00142	DR999_PMT10882	A0A4D9F019	A0A4D9E8P2	Mastermind-like protein 3.	Tyrosine-protein kinase receptor.	0.797
DR999_PMT00142	DR999_PMT11075	A0A4D9F019	A0A4D9E7F1	Mastermind-like protein 3.	Insulin receptor substrate 1.	0.722
DR999_PMT00142	DR999_PMT11285	A0A4D9F019	A0A4D9EC75	Mastermind-like protein 3.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.828
DR999_PMT00142	DR999_PMT12797	A0A4D9F019	A0A4D9E7T4	Mastermind-like protein 3.	Growth factor receptor-bound protein 2.	0.997
DR999_PMT00142	DR999_PMT16034	A0A4D9F019	A0A4D9E085	Mastermind-like protein 3.	Adapter molecule crk.	0.925
DR999_PMT00142	DR999_PMT20500	A0A4D9F019	A0A4D9DJZ0	Mastermind-like protein 3.	Rhodopsin kinase-like.	0.869
DR999_PMT00995	DR999_PMT00142	A0A4D9F744	A0A4D9F019	Relaxin receptor 1-like.	Mastermind-like protein 3.	0.722
DR999_PMT00995	DR999_PMT02426	A0A4D9F744	A0A4D9F3F6	Relaxin receptor 1-like.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.912
DR999_PMT00995	DR999_PMT02648	A0A4D9F744	A0A4D9F2U9	Relaxin receptor 1-like.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.912
DR999_PMT00995	DR999_PMT03467	A0A4D9F744	A0A4D9ERL5	Relaxin receptor 1-like.	Tyrosine-protein kinase receptor.	0.950
DR999_PMT00995	DR999_PMT06208	A0A4D9F744	A0A4D9EJ96	Relaxin receptor 1-like.	Receptor protein-tyrosine kinase.	0.533