(31 nodes) Regulation of chondrocyte differentiation network (Platysternon megacephalum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DR999_PMT20660	Arachidonate 5-lipoxygenase. (666 aa)
	DR999_PMT02322	Protein HIRA-like; Belongs to the membrane-bound acyltransferase family. (518 aa)
	DR999_PMT01733	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
	DR999_PMT02426	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	DR999_PMT02648	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	DR999_PMT04223	Serine/threonine-protein kinase D3-like. (1294 aa)
	DR999_PMT05031	Cleavage and polyadenylation specificity factor subunit 6. (198 aa)
	DR999_PMT00379	ATP-dependent RNA helicase DDX24. (463 aa)
	DR999_PMT01270	Gremlin. (184 aa)
	DR999_PMT07291	Origin recognition complex subunit 6. (717 aa)
	DR999_PMT01413	Paired mesoderm homeobox protein 2B. (142 aa)
	DR999_PMT03841	Protein MAL2. (209 aa)
	DR999_PMT07895	TGF_BETA_2 domain-containing protein. (476 aa)
	DR999_PMT05118	A disintegrin and metalloproteinase with thrombospondin motifs 12. (629 aa)
	DR999_PMT11231	Sepiapterin reductase. (178 aa)
	DR999_PMT10002	Prostate stem cell antigen-like. (745 aa)
	DR999_PMT11257	Perilipin-3-like. (393 aa)
	DR999_PMT11247	ER degradation-enhancing alpha-mannosidase-like protein 2. (232 aa)
	DR999_PMT12353	Growth/differentiation factor 5. (500 aa)
	DR999_PMT11986	Synaptotagmin-like protein 4. (416 aa)
	DR999_PMT14475	V-type proton ATPase 21 kDa proteolipid subunit. (781 aa)
	DR999_PMT11405	Homeobox protein Nkx-3.2. (311 aa)
	DR999_PMT15838	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	DR999_PMT14603	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase. (507 aa)
	DR999_PMT11786	Clathrin heavy chain linker domain-containing protein 1. (177 aa)
	DR999_PMT13185	Palmitoyltransferase ZDHHC9. (1535 aa)
	DR999_PMT14358	Syntaxin-6. (1572 aa)
	DR999_PMT18080	Apolipoprotein A-II-like. (186 aa)
	DR999_PMT19457	Tyrosine-protein kinase STYK1-like. (1063 aa)
	DR999_PMT21393	Perforin-1-like; Belongs to the heparin-binding growth factors family. (363 aa)
	DR999_PMT17232	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)

Your Current Organism:

Platysternon megacephalum

NCBI taxonomy Id: 55544
Other names: P. megacephalum, Platysternon macrocephalus, big-headed turtle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR999_PMT00379	DR999_PMT02322	A0A4D9EX32	A0A4D9F9R6	ATP-dependent RNA helicase DDX24.	Protein HIRA-like; Belongs to the membrane-bound acyltransferase family.	0.480
DR999_PMT01270	DR999_PMT07895	A0A4D9EWI3	A0A4D9EPS0	Gremlin.	TGF_BETA_2 domain-containing protein.	0.832
DR999_PMT01413	DR999_PMT02426	A0A4D9EUR6	A0A4D9F3F6	Paired mesoderm homeobox protein 2B.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.529
DR999_PMT01413	DR999_PMT02648	A0A4D9EUR6	A0A4D9F2U9	Paired mesoderm homeobox protein 2B.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.529
DR999_PMT01733	DR999_PMT02426	A0A4D9F5B6	A0A4D9F3F6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.565
DR999_PMT01733	DR999_PMT02648	A0A4D9F5B6	A0A4D9F2U9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.565
DR999_PMT02322	DR999_PMT00379	A0A4D9F9R6	A0A4D9EX32	Protein HIRA-like; Belongs to the membrane-bound acyltransferase family.	ATP-dependent RNA helicase DDX24.	0.480
DR999_PMT02322	DR999_PMT14603	A0A4D9F9R6	A0A4D9E470	Protein HIRA-like; Belongs to the membrane-bound acyltransferase family.	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase.	0.480
DR999_PMT02426	DR999_PMT01413	A0A4D9F3F6	A0A4D9EUR6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Paired mesoderm homeobox protein 2B.	0.529
DR999_PMT02426	DR999_PMT01733	A0A4D9F3F6	A0A4D9F5B6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.565
DR999_PMT02426	DR999_PMT02648	A0A4D9F3F6	A0A4D9F2U9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.816
DR999_PMT02426	DR999_PMT14475	A0A4D9F3F6	A0A4D9E847	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	V-type proton ATPase 21 kDa proteolipid subunit.	0.479
DR999_PMT02426	DR999_PMT21393	A0A4D9F3F6	A0A4D9DHP0	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Perforin-1-like; Belongs to the heparin-binding growth factors family.	0.565
DR999_PMT02648	DR999_PMT01413	A0A4D9F2U9	A0A4D9EUR6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Paired mesoderm homeobox protein 2B.	0.529
DR999_PMT02648	DR999_PMT01733	A0A4D9F2U9	A0A4D9F5B6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.565
DR999_PMT02648	DR999_PMT02426	A0A4D9F2U9	A0A4D9F3F6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.816
DR999_PMT02648	DR999_PMT14475	A0A4D9F2U9	A0A4D9E847	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	V-type proton ATPase 21 kDa proteolipid subunit.	0.479
DR999_PMT02648	DR999_PMT21393	A0A4D9F2U9	A0A4D9DHP0	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Perforin-1-like; Belongs to the heparin-binding growth factors family.	0.565
DR999_PMT05031	DR999_PMT05118	A0A4D9EX54	A0A4D9EMG0	Cleavage and polyadenylation specificity factor subunit 6.	A disintegrin and metalloproteinase with thrombospondin motifs 12.	0.825
DR999_PMT05118	DR999_PMT05031	A0A4D9EMG0	A0A4D9EX54	A disintegrin and metalloproteinase with thrombospondin motifs 12.	Cleavage and polyadenylation specificity factor subunit 6.	0.825