(9 nodes) Hepatocyte differentiation network (Platysternon megacephalum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DR999_PMT23340	Molecular chaperone DnaJ. (141 aa)
	DR999_PMT21017	NACHT, LRR and PYD domains-containing protein 1-like. (558 aa)
	DR999_PMT20298	Mitogen-activated protein kinase 3. (98 aa)
	DR999_PMT02533	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (386 aa)
	DR999_PMT00873	Annexin. (342 aa)
	DR999_PMT05518	Telethonin. (984 aa)
	DR999_PMT03685	Origin recognition complex subunit 3. (558 aa)
	DR999_PMT05314	PWWP domain-containing protein 2A. (951 aa)
	DR999_PMT12378	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2. (622 aa)

Your Current Organism:

Platysternon megacephalum

NCBI taxonomy Id: 55544
Other names: P. megacephalum, Platysternon macrocephalus, big-headed turtle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR999_PMT05314	DR999_PMT05518	A0A4D9EME1	A0A4D9ESW4	PWWP domain-containing protein 2A.	Telethonin.	0.679
DR999_PMT05518	DR999_PMT05314	A0A4D9ESW4	A0A4D9EME1	Telethonin.	PWWP domain-containing protein 2A.	0.679
DR999_PMT12378	DR999_PMT21017	A0A4D9EAQ7	A0A4D9DI64	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	NACHT, LRR and PYD domains-containing protein 1-like.	0.708
DR999_PMT12378	DR999_PMT23340	A0A4D9EAQ7	A0A4D9DDQ2	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	Molecular chaperone DnaJ.	0.718
DR999_PMT21017	DR999_PMT12378	A0A4D9DI64	A0A4D9EAQ7	NACHT, LRR and PYD domains-containing protein 1-like.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	0.708
DR999_PMT21017	DR999_PMT23340	A0A4D9DI64	A0A4D9DDQ2	NACHT, LRR and PYD domains-containing protein 1-like.	Molecular chaperone DnaJ.	0.951
DR999_PMT23340	DR999_PMT12378	A0A4D9DDQ2	A0A4D9EAQ7	Molecular chaperone DnaJ.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2.	0.718
DR999_PMT23340	DR999_PMT21017	A0A4D9DDQ2	A0A4D9DI64	Molecular chaperone DnaJ.	NACHT, LRR and PYD domains-containing protein 1-like.	0.951