STRINGSTRING
SDH05299.1 SDH05299.1 SDH05049.1 SDH05049.1 SDH05020.1 SDH05020.1 ftsB ftsB SDG90141.1 SDG90141.1 ffh ffh secF secF secD secD yajC yajC SDG70272.1 SDG70272.1 SDG69209.1 SDG69209.1 SDG69182.1 SDG69182.1 SDG78794.1 SDG78794.1 SDG78014.1 SDG78014.1 SDG77008.1 SDG77008.1 SDG76983.1 SDG76983.1 SDG76966.1 SDG76966.1 SDG76939.1 SDG76939.1 SDG76915.1 SDG76915.1 SDG76891.1 SDG76891.1 SDG76877.1 SDG76877.1 SDG76850.1 SDG76850.1 SDG76826.1 SDG76826.1 SDG76801.1 SDG76801.1 SDG76788.1 SDG76788.1 SDG73383.1 SDG73383.1 SDG73306.1 SDG73306.1 SDG73273.1 SDG73273.1 SDG72073.1 SDG72073.1 SDG72024.1 SDG72024.1 SDG71543.1 SDG71543.1 clpB clpB secB secB tatC tatC tatB tatB tatA-2 tatA-2 SDG60563.1 SDG60563.1 SDG60536.1 SDG60536.1 SDG60444.1 SDG60444.1 SDI03116.1 SDI03116.1 SDI02990.1 SDI02990.1 SDH99825.1 SDH99825.1 SDH99802.1 SDH99802.1 SDH99777.1 SDH99777.1 lptC lptC SDH93128.1 SDH93128.1 SDH86344.1 SDH86344.1 SDH85463.1 SDH85463.1 secA secA SDH69159.1 SDH69159.1 SDH69109.1 SDH69109.1 SDG29387.1 SDG29387.1 secE secE SDI07846.1 SDI07846.1 SDG33160.1 SDG33160.1 SDG33461.1 SDG33461.1 SDG36778.1 SDG36778.1 SDG36835.1 SDG36835.1 SDG36990.1 SDG36990.1 SDG37111.1 SDG37111.1 SDG37145.1 SDG37145.1 SDG37199.1 SDG37199.1 SDG37232.1 SDG37232.1 SDG37289.1 SDG37289.1 tatA tatA SDG50880.1 SDG50880.1 SDG50905.1 SDG50905.1 SDG50930.1 SDG50930.1 SDG50960.1 SDG50960.1 SDG51016.1 SDG51016.1 SDG51048.1 SDG51048.1 SDG51072.1 SDG51072.1 SDG51139.1 SDG51139.1 SDG58208.1 SDG58208.1 SDH69077.1 SDH69077.1 SDH69051.1 SDH69051.1 SDH69022.1 SDH69022.1 SDH68993.1 SDH68993.1 SDH68964.1 SDH68964.1 SDH68937.1 SDH68937.1 SDH68912.1 SDH68912.1 SDH68884.1 SDH68884.1 ftsY ftsY yidC yidC SDH25733.1 SDH25733.1 secY secY SDH00851.1 SDH00851.1 SDH00791.1 SDH00791.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDH05299.1General secretion pathway protein E. (594 aa)
SDH05049.1Type VI secretion system secreted protein VgrG. (695 aa)
SDH05020.1Type VI secretion system secreted protein Hcp. (172 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (92 aa)
SDG90141.1Serine/threonine protein kinase. (526 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] (457 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (301 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (622 aa)
yajCProtein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
SDG70272.1Transglycosylase SLT domain-containing protein. (190 aa)
SDG69209.1Serine/threonine protein kinase. (505 aa)
SDG69182.1Protein phosphatase. (261 aa)
SDG78794.1Soluble lytic murein transglycosylase. (642 aa)
SDG78014.1Uncharacterized protein; Belongs to the UPF0149 family. (195 aa)
SDG77008.1General secretion pathway protein M. (176 aa)
SDG76983.1General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (378 aa)
SDG76966.1General secretion pathway protein K. (321 aa)
SDG76939.1General secretion pathway protein J. (229 aa)
SDG76915.1General secretion pathway protein I. (129 aa)
SDG76891.1General secretion pathway protein H. (176 aa)
SDG76877.1General secretion pathway protein G. (145 aa)
SDG76850.1General secretion pathway protein F. (405 aa)
SDG76826.1General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (495 aa)
SDG76801.1General secretion pathway protein C. (214 aa)
SDG76788.1General secretion pathway protein D. (643 aa)
SDG73383.1Type IVB pilus formation outer membrane protein, R64 PilN family. (577 aa)
SDG73306.1Type II/IV secretion system protein. (465 aa)
SDG73273.1Hypothetical protein. (69 aa)
SDG72073.1Hypothetical protein. (187 aa)
SDG72024.1Conjugative coupling factor TraD, TOL family. (713 aa)
SDG71543.1Type IV pilus biogenesis. (203 aa)
clpBATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (854 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (161 aa)
tatCSec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (264 aa)
tatBSec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (120 aa)
tatA-2Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (76 aa)
SDG60563.1Type IV pilus assembly protein PilM. (354 aa)
SDG60536.1Type IV pilus assembly protein PilN. (191 aa)
SDG60444.1Type IV pilus assembly protein PilQ. (693 aa)
SDI03116.1SEC-C motif-containing protein. (72 aa)
SDI02990.1SEC-C motif-containing protein; Belongs to the UPF0225 family. (161 aa)
SDH99825.1Leader peptidase (prepilin peptidase) / N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (289 aa)
SDH99802.1Type IV pilus assembly protein PilC. (406 aa)
SDH99777.1Type IV pilus assembly protein PilB. (566 aa)
lptCLipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (189 aa)
SDH93128.1Membrane fusion protein, adhesin transport system. (457 aa)
SDH86344.1Prepilin peptidase CpaA. (166 aa)
SDH85463.1Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB. (744 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (911 aa)
SDH69159.1General secretion pathway protein D. (731 aa)
SDH69109.1Type II secretion system (T2SS), protein M subtype b. (197 aa)
SDG29387.1Serine/threonine protein phosphatase PrpC. (555 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (122 aa)
SDI07846.1Membrane fusion protein, adhesin transport system. (452 aa)
SDG33160.1Type II and III secretion system protein. (269 aa)
SDG33461.1ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (756 aa)
SDG36778.1Type VI secretion system secreted protein VgrG. (741 aa)
SDG36835.1Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family. (900 aa)
SDG36990.1Type VI secretion system secreted protein Hcp. (162 aa)
SDG37111.1FHA domain protein. (465 aa)
SDG37145.1Type VI secretion system protein VasD. (150 aa)
SDG37199.1Type VI secretion system protein ImpK. (454 aa)
SDG37232.1Type VI secretion system protein ImpL. (1170 aa)
SDG37289.1Serine/threonine protein phosphatase Stp1. (243 aa)
tatASec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (56 aa)
SDG50880.1Type IV pilus assembly protein PilW. (331 aa)
SDG50905.1Type IV pilus assembly protein PilV. (153 aa)
SDG50930.1Type IV fimbrial biogenesis protein FimT. (157 aa)
SDG50960.1Type IV fimbrial biogenesis protein FimT. (141 aa)
SDG51016.1Hypothetical protein. (170 aa)
SDG51048.1Type IV pilus assembly protein PilW. (395 aa)
SDG51072.1Type IV pilus assembly protein PilV. (191 aa)
SDG51139.1Type IV fimbrial biogenesis protein FimT. (171 aa)
SDG58208.1Outer membrane protein. (478 aa)
SDH69077.1General secretion pathway protein L. (369 aa)
SDH69051.1General secretion pathway protein K. (300 aa)
SDH69022.1General secretion pathway protein J. (220 aa)
SDH68993.1General secretion pathway protein I. (130 aa)
SDH68964.1General secretion pathway protein H. (188 aa)
SDH68937.1General secretion pathway protein G. (148 aa)
SDH68912.1General secretion pathway protein F. (406 aa)
SDH68884.1General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (573 aa)
ftsYFused signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (456 aa)
yidCYidC/Oxa1 family membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (577 aa)
SDH25733.1Hypothetical protein. (531 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (442 aa)
SDH00851.1Hypothetical protein. (206 aa)
SDH00791.1Conjugative coupling factor TraD, TOL family. (718 aa)
Your Current Organism:
Pseudomonas benzenivorans
NCBI taxonomy Id: 556533
Other names: CIP 109857, DSM 8628, P. benzenivorans, Pseudomonas benzenivorans Lang et al. 2012 emend. Hameed et al. 2014, Pseudomonas sp. DSM 8628
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