(38 nodes) NADP binding network (Cuculus canorus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N303_07934	Dimethylaniline monooxygenase [N-oxide-forming] 1; Belongs to the FMO family. (506 aa)
	N303_03418	GDP-mannose 4,6 dehydratase. (339 aa)
	N303_04028	7-dehydrocholesterol reductase. (475 aa)
	N303_04418	Putative oxidoreductase GLYR1. (538 aa)
	N303_00078	Methionine synthase reductase. (707 aa)
	N303_00589	Estradiol 17-beta-dehydrogenase 1. (122 aa)
	N303_02782	Dihydropteridine reductase. (65 aa)
	N303_06807	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (271 aa)
	N303_06808	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (266 aa)
	N303_09332	Nitric oxide synthase; Produces nitric oxide (NO). (1430 aa)
	N303_06391	Uncharacterized protein. (313 aa)
	N303_00950	3-hydroxy-3-methylglutaryl coenzyme A reductase. (881 aa)
	N303_07935	Dimethylaniline monooxygenase [N-oxide-forming] 4; Belongs to the FMO family. (510 aa)
	N303_03485	Quinone oxidoreductase PIG3. (347 aa)
	N303_07933	Dimethylaniline monooxygenase [N-oxide-forming] 3; Belongs to the FMO family. (496 aa)
	N303_12556	Voltage-gated potassium channel subunit beta-1. (142 aa)
	N303_05627	Voltage-gated potassium channel subunit beta-2. (338 aa)
	N303_02267	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (306 aa)
	N303_13997	Dihydrofolate reductase. (143 aa)
	N303_02571	6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (482 aa)
	N303_04968	Corticosteroid 11-beta-dehydrogenase isozyme 1. (220 aa)
	N303_04858	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (292 aa)
	N303_04052	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (507 aa)
	N303_13290	Quinone oxidoreductase. (331 aa)
	N303_13313	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (948 aa)
	N303_02391	Malic enzyme. (543 aa)
	N303_02336	Malic enzyme. (542 aa)
	N303_13102	Ketimine reductase mu-crystallin. (256 aa)
	N303_07045	Carbonyl reductase family member 4. (241 aa)
	N303_11555	Dimethylaniline monooxygenase [N-oxide-forming] 5; Belongs to the FMO family. (495 aa)
	N303_15805	Glyceraldehyde-3-phosphate dehydrogenase. (325 aa)
	N303_13811	Lamin-B receptor. (613 aa)
	N303_12557	Voltage-gated potassium channel subunit beta-1. (218 aa)
	N303_12083	NADPH--cytochrome P450 reductase. (680 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (592 aa)
	N303_04969	Corticosteroid 11-beta-dehydrogenase isozyme 1. (292 aa)
	N303_11556	Dimethylaniline monooxygenase [N-oxide-forming] 5; Belongs to the FMO family. (495 aa)
	N303_14688	Uncharacterized protein. (421 aa)

Your Current Organism:

Cuculus canorus

NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N303_00078	N303_03485	A0A091FNL3	A0A091G067	Methionine synthase reductase.	Quinone oxidoreductase PIG3.	0.413
N303_00078	N303_04052	A0A091FNL3	A0A091G7K8	Methionine synthase reductase.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.602
N303_00078	N303_13290	A0A091FNL3	A0A091GA94	Methionine synthase reductase.	Quinone oxidoreductase.	0.413
N303_00589	N303_00950	A0A091FNQ8	A0A091FX76	Estradiol 17-beta-dehydrogenase 1.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.449
N303_00589	N303_03485	A0A091FNQ8	A0A091G067	Estradiol 17-beta-dehydrogenase 1.	Quinone oxidoreductase PIG3.	0.470
N303_00589	N303_04858	A0A091FNQ8	A0A091G712	Estradiol 17-beta-dehydrogenase 1.	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.470
N303_00589	N303_06807	A0A091FNQ8	A0A091FUF2	Estradiol 17-beta-dehydrogenase 1.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.470
N303_00589	N303_06808	A0A091FNQ8	A0A091FVL8	Estradiol 17-beta-dehydrogenase 1.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.470
N303_00589	N303_13290	A0A091FNQ8	A0A091GA94	Estradiol 17-beta-dehydrogenase 1.	Quinone oxidoreductase.	0.470
N303_00589	N303_14688	A0A091FNQ8	A0A091H126	Estradiol 17-beta-dehydrogenase 1.	Uncharacterized protein.	0.508
N303_00589	N303_15805	A0A091FNQ8	A0A091GER7	Estradiol 17-beta-dehydrogenase 1.	Glyceraldehyde-3-phosphate dehydrogenase.	0.524
N303_00950	N303_00589	A0A091FX76	A0A091FNQ8	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Estradiol 17-beta-dehydrogenase 1.	0.449
N303_00950	N303_02336	A0A091FX76	A0A091GCG5	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Malic enzyme.	0.407
N303_00950	N303_02391	A0A091FX76	A0A091GAE0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Malic enzyme.	0.407
N303_00950	N303_02782	A0A091FX76	A0A091FNU0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Dihydropteridine reductase.	0.415
N303_00950	N303_04028	A0A091FX76	A0A091FKP5	3-hydroxy-3-methylglutaryl coenzyme A reductase.	7-dehydrocholesterol reductase.	0.657
N303_00950	N303_04052	A0A091FX76	A0A091G7K8	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.486
N303_00950	N303_04968	A0A091FX76	A0A091G687	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Corticosteroid 11-beta-dehydrogenase isozyme 1.	0.449
N303_00950	N303_04969	A0A091FX76	A0A091GRU7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Corticosteroid 11-beta-dehydrogenase isozyme 1.	0.449
N303_00950	N303_06391	A0A091FX76	A0A091FWU2	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.424