(90 nodes) ATPases associated with a variety of cellular activities network (Cuculus canorus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	N303_13806	Nuclear valosin-containing protein-like. (857 aa)
	N303_12497	U5 small nuclear ribonucleoprotein 200 kDa helicase. (1629 aa)
	N303_09078	Multidrug resistance-associated protein 7. (1485 aa)
	N303_01955	ATP-dependent zinc metalloprotease YME1L1. (706 aa)
	N303_10281	ATP-binding cassette sub-family F member 3. (662 aa)
	N303_06080	Torsin-2A. (267 aa)
	N303_09911	Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family. (346 aa)
	N303_08019	DNA replication licensing factor MCM3; Belongs to the MCM family. (746 aa)
	N303_01617	AFG3-like 2. (767 aa)
	N303_03335	ATP-binding cassette sub-family A member 8-B. (1537 aa)
	N303_10189	Replication factor C subunit 3. (327 aa)
	N303_02245	Von Willebrand factor A domain-containing protein 8. (1830 aa)
	N303_08945	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1472 aa)
	N303_06800	Pachytene checkpoint protein 2; Belongs to the AAA ATPase family. (411 aa)
	N303_10028	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	KATNA1-2	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily. (489 aa)
	N303_13680	Uncharacterized protein. (738 aa)
	N303_04265	Spermatogenesis-associated protein 5. (721 aa)
	N303_12833	Vesicle-fusing ATPase. (716 aa)
	N303_14330	Vacuolar protein sorting-associated protein 4A. (163 aa)
	N303_02185	Putative ATP-dependent RNA helicase DHX37. (1110 aa)
	N303_05989	Uncharacterized protein. (607 aa)
	N303_07198	Bile salt export pump. (1326 aa)
	N303_13564	ATP-binding cassette sub-family B member 9. (752 aa)
	N303_09092	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (411 aa)
	N303_15644	ATPase family AAA domain-containing protein 5. (1777 aa)
	N303_06561	ATP-binding cassette sub-family A member 1. (2199 aa)
	N303_13303	ATP-binding cassette sub-family D member 3. (623 aa)
	N303_14389	Neuron navigator 3. (2384 aa)
	N303_15677	Canalicular multispecific organic anion transporter 2. (1497 aa)
	N303_03436	Vacuolar protein sorting-associated protein 4B. (145 aa)
	N303_14458	ATP-binding cassette sub-family F member 2. (569 aa)
	N303_01814	ATP-binding cassette sub-family D member 4. (573 aa)
	N303_03843	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (862 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (492 aa)
	N303_10605	Paraplegin. (739 aa)
	N303_13914	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (409 aa)
	N303_12201	DNA helicase MCM9; Belongs to the MCM family. (1161 aa)
	N303_01167	ATP-binding cassette sub-family C member 9. (1556 aa)
	N303_02955	DNA helicase; Belongs to the MCM family. (839 aa)
	N303_14839	Torsin-4A-A. (424 aa)
	N303_07330	Fidgetin-like 1; Belongs to the AAA ATPase family. (691 aa)
	N303_13382	Uncharacterized protein. (586 aa)
	N303_04959	Torsin-3A. (266 aa)
	N303_11863	Multidrug resistance-associated protein 1. (1485 aa)
	N303_03478	ATPase family AAA domain-containing protein 2B. (968 aa)
	N303_09481	ATP-binding cassette sub-family G member 2. (595 aa)
	N303_08029	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (439 aa)
	N303_07575	ATP-binding cassette sub-family G member 5. (645 aa)
	N303_10303	Replication factor C subunit 4. (361 aa)
	N303_14958	ATP-binding cassette sub-family G member 1. (670 aa)
	N303_13990	Cell cycle checkpoint protein RAD17. (672 aa)
	N303_10277	Multidrug resistance-associated protein 5. (1435 aa)
	N303_15492	Cytoplasmic dynein 1 heavy chain 1. (4570 aa)
	N303_13981	Peroxisome biogenesis factor 1. (1252 aa)
	N303_03336	ATP-binding cassette sub-family A member 5. (1592 aa)
	N303_05863	ATP-binding cassette sub-family D member 2. (667 aa)
	N303_03986	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (361 aa)
	N303_00508	DNA-binding protein SMUBP-2. (957 aa)
	N303_07177	Fidgetin; Belongs to the AAA ATPase family. (751 aa)
	N303_12334	Multidrug resistance-associated protein 4. (1305 aa)
	N303_00141	ATP-binding cassette sub-family C member 8. (1543 aa)
	N303_05228	ATPase family AAA domain-containing protein 3. (533 aa)
	N303_01270	DNA helicase MCM8; Belongs to the MCM family. (780 aa)
	N303_10405	Lon protease homolog; Belongs to the peptidase S16 family. (775 aa)
	N303_00280	Midasin. (5599 aa)
	N303_04434	ATP-binding cassette sub-family A member 3. (1700 aa)
	N303_03719	Dynein heavy chain 5, axonemal. (4608 aa)
	N303_11744	ATP-binding cassette sub-family E member 1. (600 aa)
	N303_06300	Multidrug resistance protein 1. (1227 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (467 aa)
	N303_04024	Neuron navigator 2. (2300 aa)
	N303_08723	Dynein heavy chain 10, axonemal. (4032 aa)
	N303_12528	Replication factor C subunit 2. (316 aa)
	N303_03668	Uncharacterized protein. (684 aa)
	N303_13907	DNA helicase; Belongs to the MCM family. (888 aa)
	N303_07833	Uncharacterized protein. (666 aa)
	N303_03688	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (425 aa)
	N303_10501	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (368 aa)
	N303_08175	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (424 aa)
	N303_10255	Spastin; Belongs to the AAA ATPase family. (477 aa)
	N303_15267	ATP-binding cassette sub-family A member 1. (2185 aa)
	N303_14882	Cytoplasmic dynein 2 heavy chain 1. (3808 aa)
	N303_08398	Replication factor C subunit 1. (1143 aa)
	N303_05116	Chromosome transmission fidelity protein 18. (250 aa)
	N303_09608	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (363 aa)
	N303_14154	Canalicular multispecific organic anion transporter 1. (1561 aa)
	N303_11896	Cytosolic Fe-S cluster assembly factor nubp1. (283 aa)
	N303_11864	Multidrug resistance-associated protein 1. (1512 aa)
	N303_07777	ATPase family AAA domain-containing protein 2. (864 aa)

Your Current Organism:

Cuculus canorus

NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KATNA1	KATNAL2	A0A091G6A3	A0A091FMX8	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.480
KATNA1	N303_03436	A0A091G6A3	A0A091G8M4	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Vacuolar protein sorting-associated protein 4B.	0.413
KATNA1	N303_03843	A0A091G6A3	A0A091G6G4	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.529
KATNA1	N303_03986	A0A091G6A3	A0A091FVQ9	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.775
KATNA1	N303_04265	A0A091G6A3	A0A091GFD7	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Spermatogenesis-associated protein 5.	0.489
KATNA1	N303_06800	A0A091G6A3	A0A091GGI3	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Pachytene checkpoint protein 2; Belongs to the AAA ATPase family.	0.459
KATNA1	N303_07177	A0A091G6A3	A0A091FSQ7	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Fidgetin; Belongs to the AAA ATPase family.	0.449
KATNA1	N303_07330	A0A091G6A3	A0A091G438	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Fidgetin-like 1; Belongs to the AAA ATPase family.	0.473
KATNA1	N303_08175	A0A091G6A3	A0A091GLN1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.778
KATNA1	N303_09608	A0A091G6A3	A0A091GRW1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family.	0.482
KATNA1	N303_10255	A0A091G6A3	A0A091GLM1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Spastin; Belongs to the AAA ATPase family.	0.489
KATNA1	N303_12833	A0A091G6A3	A0A091GEU4	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Vesicle-fusing ATPase.	0.483
KATNA1	N303_13806	A0A091G6A3	A0A091GN68	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Nuclear valosin-containing protein-like.	0.485
KATNA1	N303_13914	A0A091G6A3	A0A091G5G5	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.573
KATNA1	N303_13981	A0A091G6A3	A0A091FYD8	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Peroxisome biogenesis factor 1.	0.488
KATNA1	N303_14330	A0A091G6A3	A0A091GEJ5	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	Vacuolar protein sorting-associated protein 4A.	0.415
KATNA1-2	KATNAL2	A0A091GG87	A0A091FMX8	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.478
KATNA1-2	N303_03436	A0A091GG87	A0A091G8M4	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	Vacuolar protein sorting-associated protein 4B.	0.431
KATNA1-2	N303_03843	A0A091GG87	A0A091G6G4	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.518
KATNA1-2	N303_03986	A0A091GG87	A0A091FVQ9	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.774