(36 nodes) Cytosolic DNA-sensing pathway network (Cuculus canorus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N303_12599	DNA-directed RNA polymerase III subunit RPC3. (56 aa)
	N303_14852	Interferon. (165 aa)
	N303_11341	Interleukin-18. (193 aa)
	N303_09073	DNA-directed RNA polymerases I and III subunit RPAC1. (323 aa)
	N303_09899	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (136 aa)
	N303_15270	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (192 aa)
	N303_13042	C-C motif chemokine. (91 aa)
	N303_06337	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (55 aa)
	N303_13095	DNA-directed RNA polymerase III subunit RPC5. (684 aa)
	N303_04745	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1104 aa)
	N303_05785	Mitochondrial antiviral-signaling protein. (646 aa)
	N303_10767	Interferon alpha-2. (182 aa)
	N303_02302	Cyclic GMP-AMP synthase. (356 aa)
	N303_14036	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1374 aa)
	N303_06306	Interleukin-6. (151 aa)
	N303_01788	NF-kappa-B inhibitor alpha. (238 aa)
	N303_03410	Receptor-interacting serine/threonine-protein kinase 1. (663 aa)
	N303_05352	Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (553 aa)
	N303_05453	Inhibitor of nuclear factor kappa-B kinase subunit beta. (690 aa)
	N303_00201	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	N303_00210	Interferon regulatory factor 3. (459 aa)
	N303_04515	Serine/threonine-protein kinase TBK1. (743 aa)
	N303_01192	Proto-oncogene c-Rel. (591 aa)
	N303_02836	DNA-directed RNA polymerase III subunit RPC8. (206 aa)
	N303_13043	C-C motif chemokine 4. (90 aa)
	N303_13041	C-C motif chemokine. (91 aa)
	N303_00672	Double-stranded RNA-specific adenosine deaminase. (1028 aa)
	N303_04828	DNA-directed RNA polymerase III subunit RPC7. (210 aa)
	N303_13044	C-C motif chemokine. (65 aa)
	N303_10294	DNA-directed RNA polymerases I, II, and III subunit RPABC3. (142 aa)
	N303_12911	Caspase-1; Belongs to the peptidase C14A family. (388 aa)
	N303_09620	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (670 aa)
	N303_06484	DNA-directed RNA polymerases I and III subunit RPAC2. (86 aa)
	N303_12266	DNA-directed RNA polymerase III subunit RPC6. (308 aa)
	N303_05401	Piwi-like 2. (456 aa)
	N303_05402	DNA-directed RNA polymerase III subunit RPC4. (396 aa)

Your Current Organism:

Cuculus canorus

NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N303_00201	N303_02836	A0A091FRW0	A0A091FVN1	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC8.	0.998
N303_00201	N303_04745	A0A091FRW0	A0A091GEU9	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
N303_00201	N303_04828	A0A091FRW0	A0A091G6Y0	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC7.	0.986
N303_00201	N303_05402	A0A091FRW0	A0A091FRD2	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC4.	0.993
N303_00201	N303_06337	A0A091FRW0	A0A091GIP9	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I, II, and III subunit RPABC4.	0.999
N303_00201	N303_06484	A0A091FRW0	A0A091G5I0	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I and III subunit RPAC2.	0.999
N303_00201	N303_09073	A0A091FRW0	A0A091GMC8	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I and III subunit RPAC1.	0.999
N303_00201	N303_09899	A0A091FRW0	A0A091GKJ6	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I, II, and III subunit RPABC2.	0.999
N303_00201	N303_10294	A0A091FRW0	A0A091G0U7	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I, II, and III subunit RPABC3.	0.999
N303_00201	N303_12266	A0A091FRW0	A0A091G627	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC6.	0.992
N303_00201	N303_12599	A0A091FRW0	A0A091H4Y3	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC3.	0.992
N303_00201	N303_13095	A0A091FRW0	A0A091GF31	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase III subunit RPC5.	0.993
N303_00201	N303_14036	A0A091FRW0	A0A091GAI3	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.997
N303_00201	N303_15270	A0A091FRW0	A0A091GK82	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I, II, and III subunit RPABC1.	0.999
N303_00210	N303_03410	A0A091FSF2	A0A091G8K8	Interferon regulatory factor 3.	Receptor-interacting serine/threonine-protein kinase 1.	0.518
N303_00210	N303_04515	A0A091FSF2	A0A091FUU6	Interferon regulatory factor 3.	Serine/threonine-protein kinase TBK1.	0.908
N303_00210	N303_05352	A0A091FSF2	A0A091G7N8	Interferon regulatory factor 3.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	0.902
N303_00210	N303_05453	A0A091FSF2	A0A091FRH0	Interferon regulatory factor 3.	Inhibitor of nuclear factor kappa-B kinase subunit beta.	0.855
N303_00210	N303_05785	A0A091FSF2	A0A091GDV1	Interferon regulatory factor 3.	Mitochondrial antiviral-signaling protein.	0.566
N303_00210	N303_06306	A0A091FSF2	A0A091GA98	Interferon regulatory factor 3.	Interleukin-6.	0.525