STRINGSTRING
C5DDD6_LACTC C5DDD6_LACTC C5DE39_LACTC C5DE39_LACTC C5DF75_LACTC C5DF75_LACTC C5DFV4_LACTC C5DFV4_LACTC C5DH93_LACTC C5DH93_LACTC C5DIA8_LACTC C5DIA8_LACTC C5DJ41_LACTC C5DJ41_LACTC C5DJB9_LACTC C5DJB9_LACTC C5DKA6_LACTC C5DKA6_LACTC C5DKW7_LACTC C5DKW7_LACTC C5DN43_LACTC C5DN43_LACTC C5DND8_LACTC C5DND8_LACTC C5E1Z0_LACTC C5E1Z0_LACTC C5E2S9_LACTC C5E2S9_LACTC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C5DDD6_LACTCKLTH0B10428p. (1258 aa)
C5DE39_LACTCSerine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2814 aa)
C5DF75_LACTCDouble-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (664 aa)
C5DFV4_LACTCKLTH0D00132p. (1258 aa)
C5DH93_LACTCKLTH0E02398p. (665 aa)
C5DIA8_LACTCKLTH0E11044p. (275 aa)
C5DJ41_LACTCKLTH0F13310p. (1028 aa)
C5DJB9_LACTCKLTH0F15158p. (616 aa)
C5DKA6_LACTCKLTH0F03058p. (1298 aa)
C5DKW7_LACTCDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (627 aa)
C5DN43_LACTCKLTH0G14014p; Belongs to the RecA family. (333 aa)
C5DND8_LACTCKLTH0G16148p. (478 aa)
C5E1Z0_LACTCKLTH0H00770p. (1539 aa)
C5E2S9_LACTCKLTH0H07436p. (400 aa)
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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